Search Results - "MOTYKA, Bruce"

Characterization of ABH‐subtype donor‐specific antibodies in ABO‐A‐incompatible kidney transplantation by Bentall, Andrew, Jeyakanthan, Mylvaganam, Braitch, Manjit, Cairo, Christopher W., Lowary, Todd L., Maier, Stephanie, Halpin, Anne, Motyka, Bruce, Zou, Lu, West, Lori J., Ball, Simon

“…ABO‐incompatible (ABOi) transplantation requires preemptive antibody reduction; however, the relationship between antibody‐mediated rejection (AMR) and…”
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CD71 + Erythroid Cells in Human Neonates Exhibit Immunosuppressive Properties and Compromise Immune Response Against Systemic Infection in Neonatal Mice by Elahi, Shokrollah, Vega-López, Marco Antonio, Herman-Miguel, Vladimir, Ramírez-Estudillo, Carmen, Mancilla-Ramírez, Javier, Motyka, Bruce, West, Lori, Oyegbami, Olaide

“…Newborns are highly susceptible to infectious diseases. The underlying mechanism of neonatal infection susceptibility has generally been related to their…”
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A dendritic cell receptor-targeted chimeric immunotherapeutic protein (C-HBV) for the treatment of chronic hepatitis B by Ma, Allan, Motyka, Bruce, Gutfreund, Klaus, Shi, Yuenian Eric, George, Rajan

“…In chronic Hepatitis B Virus (HBV) infections HBV-specific T cells are functionally impaired. Immunotherapy may restore HBV-specific T cell responses essential…”
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A dendritic cell-targeted chimeric hepatitis B virus immunotherapeutic vaccine induces both cellular and humoral immune responses in vivo by George, Rajan, Ma, Allan, Motyka, Bruce, Shi, Yuenian Eric, Liu, Qiang, Griebel, Philip

“…Chimigen® HBV Immunotherapeutic Vaccine (C-HBV), a recombinant chimeric fusion protein comprising hepatitis B virus (HBV) S1 and S2 surface antigen fragments,…”
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ABO blood group is involved in the quality of the specific immune response anti-SARS-CoV-2 by Gil-Manso, Sergio, Miguens Blanco, Iria, Motyka, Bruce, Halpin, Anne, López-Esteban, Rocío, Pérez-Fernández, Verónica Astrid, Carbonell, Diego, López-Fernández, Luis Andrés, West, Lori, Correa-Rocha, Rafael, Pion, Marjorie

“…Since December 2019, the coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread throughout…”
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Identification of a Novel Human Granzyme B Inhibitor Secreted by Cultured Sertoli Cells by Sipione, Simonetta, Simmen, Katia C, Lord, Sarah J, Motyka, Bruce, Ewen, Catherine, Shostak, Irene, Rayat, Gina R, Dufour, Jannette M, Korbutt, Greg S, Rajotte, Ray V, Bleackley, R. Chris

“…Sertoli cells have long since been recognized for their ability to suppress the immune system and protect themselves as well as other cell types from harmful…”
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ABO SELF-TOLERANCE IN A MOUSE MODEL: EVIDENCE OF TOLERANCE AT B CELL BUT NOT T CELL LEVEL by Adam, Ibrahim, Motyka, Bruce, Cowan, Peter, West, Lori J.

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425.4: The Role of Role of Sex and T Cells in Natural vs Induced ABO Antibody Production in Mice by Adam, Ibrahim, Motyka, Bruce, Tao, Kesheng, Cowan, Peter J., West, Lori J.

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221.1: ABO-incompatible transplantation following enzymatic A-antigen removal in a mouse model: A-antigen re-expression and prevention of early antibody-mediated rejection by Erickson, Tate, Motyka, Bruce, Tao, Kesheng, Pearcey, Jean, Rahfeld, Peter, Kizhakkedathu, Jayachandran N, Cypel, Marcelo, Cowan, Peter J, Withers, Stephen G, West, Lori J

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Sex, T Cells, and the Microbiome in Natural ABO Antibody Production in Mice by Adam, Ibrahim, Motyka, Bruce, Tao, Kesheng, Jeyakanthan, Mylvaganam, Alegre, Maria-Luisa, Cowan, Peter J, West, Lori J

“…"Natural" ABO antibodies (Abs) are produced without known exposure to A/B carbohydrate antigens, posing significant risks for hyperacute rejection during…”
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Sex, T Cells, and the Microbiome in Natural ABO Antibody Production in Mice by Adam, Ibrahim, Motyka, Bruce, Tao, Kesheng, Jeyakanthan, Mylvaganam, Alegre, Maria-Luisa, Cowan, Peter J., West, Lori J.

“…"Natural" ABO antibodies (Abs) are produced without known exposure to A/B carbohydrate antigens, posing significant risks for hyperacute rejection during…”
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FEMALE COMPLEXITY: HIGH ‘NATURAL’ ABO ANTI-A ANTIBODIES AND IGG CLASS SWITCH IN FEMALE VS MALE MICE by Anjum, Bushra, Adam, Ibrahim, Fersovich, Jordana, Sulzer, Maurits, Pearcey, Jean, Tao, Kesheng, Motyka, Bruce, West, Lori J.

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Antibody Response to Non-Self Blood Group A-Antigen depends on CD4 T Cells, Forigen Protein and CD22 Interaction by Adam, Ibrahim, Motyka, Bruce, Pearcey, Jean, Tao, Kesheng, Cowan, Peter, West, Lori

“…BACKGROUNDABO-incompatible heart transplantation (ABOi-HTx) is safe during infancy and allows increased donor access. B-cell tolerance develops to donor…”
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AT1R Antibody Assessment: How Should We Interpret Positive Results? by Halpin, Anne, Abou-Zeki, Sally, Larsen, Ingrid, Campbell, Patricia, Urschel, Simon, Motyka, Bruce, West, Lori J

“…INTRODUCTIONThe angiotensin II type 1 receptor (AT1R) is a G-protein-coupled receptor that is expressed on vascular endothelium. It can signal cell growth and…”
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ASSESSMENT OF ABO-HISTOCOMPATIBILITY: MODERNIZING ABO ANTIBODY DETECTION TOOLS FOR USE IN TRANSPLANTATION by Halpin, Anne, Motyka, Bruce, Pearcey, Jean, Ellis, Tess, Dijke, Esme, Lowary, Todd L., Cairo, Chris W., Sosniuk, Morgan, Maier, Stephanie, Urschel, Simon, West, Lori J.

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Alterations in the immune phenotype of thymectomized children and the development of atopic disorders after heart transplantation by Kim, Tiffany B., Ionescu, Lavinia, Avdimiretz, Nicholas, Murdoch, Faye, Larsen, Ingrid M., Motyka, Bruce, West, Lori J., Urschel, Simon

“…Background Atopic disorders are more common in children after heart transplant (HTx). We hypothesized that HTx at an early age and thymus excision (TE) affect…”
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Anti-A Antibody Response is Dependent on CD4 T Cells and Co-Engagement With Foreign Protein by Adam, Ibrahim, Motyka, Bruce, Pearcey, Jean, Tao, KeSheng, Cowan, Peter J., West, Lori J.

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Regulation of Human CD27+IgM+ B Cell Activation by Cis-Binding of the Inhibitory Molecule CD22 to CD22 Ligand (CD22L) by Dijke, Esme, Derkatz, Kim, Pearcey, Jean, Wong, Fred, Motyka, Bruce, West, Lori

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MHC-Matched A-Expressing Blood Cells Induce ABO Tolerance in Infant and Adult Mice by Motyka, Bruce, Fersovich, Jordana, Lamarche, Brendon, Sosniuk, Morgan, Adam, Ibrahim, Pearcey, Jean, Tao, Kesheng, Cairo, Christopher W, Cowan, Peter J, West, Lori J

“…PURPOSEABO-incompatible heart transplantation (ABOi HTx) is safe during infancy and allows increased donor access. Post-ABOi HTx B cell tolerance develops to…”
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OR52 AT1R antibody in pediatric heart transplant patients: What are we really detecting by Halpin, Anne, Abou-Zeki, Sally, Larsen, Ingrid, Campbell, Patricia M., Urschel, Simon, Motyka, Bruce, West, Lori

“…The frequency and impact of AT1R antibodies in pediatric heart transplantation has not been well studied. Our aim was to measure AT1R antibodies (AT1R-Ab) in…”
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