Search Results - "MOTTA, Andrea"
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Recent Advances on Nitric Oxide in the Upper Airways
Published in Current medicinal chemistry (01-07-2016)“…Exhaled nitric oxide (NO) originates from the upper airways, and takes action, to varying extents, in regulation, protection and defense, as well as in noxious…”
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Targeting gut dysbiosis against inflammation and impaired autophagy in Duchenne muscular dystrophy
Published in EMBO molecular medicine (08-03-2023)“…Nothing is known about the potential implication of gut microbiota in skeletal muscle disorders. Here, we provide evidence that fecal microbiota composition…”
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Coexistence of obesity and asthma determines a distinct respiratory metabolic phenotype
Published in Journal of allergy and clinical immunology (01-05-2017)“…Background Epidemiologic and clinical evidence supports the existence of an obesity-related asthma phenotype. No distinct pathophysiologic elements or specific…”
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4
Bacterial and viral infections and related inflammatory responses in chronic obstructive pulmonary disease
Published in Annals of medicine (Helsinki) (01-01-2021)“…In chronic obstructive pulmonary disease (COPD) patients, bacterial and viral infections play a relevant role in worsening lung function and, therefore, favour…”
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The biomarkers’ landscape of post-COVID-19 patients can suggest selective clinical interventions
Published in Scientific reports (15-12-2023)“…In COVID-19 clinical symptoms can persist even after negativization also in individuals who have had mild or moderate disease. We here investigated the…”
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Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer
Published in Pharmacological research (01-03-2023)“…In spite of the huge advancements in both diagnosis and interventions, hormone refractory prostate cancer (HRPC) remains a major hurdle in prostate cancer…”
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A Rapid Antigen Detection Test to Diagnose SARS-CoV-2 Infection Using Exhaled Breath Condensate by A Modified Inflammacheck® Device
Published in Sensors (Basel, Switzerland) (25-08-2021)“…Background: The standard test that identifies the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is based on reverse transcriptase-polymerase…”
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Clinical assessment of endothelial function in convalescent COVID-19 patients: a meta-analysis with meta-regressions
Published in Annals of medicine (Helsinki) (31-12-2022)“…Endothelial dysfunction has been proposed to play a key role in the pathogenesis of coronavirus disease 2019 (COVID-19) and its post-acute sequelae…”
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An In Vitro Model to Investigate the Role of Helicobacter pylori in Type 2 Diabetes, Obesity, Alzheimer's Disease and Cardiometabolic Disease
Published in International journal of molecular sciences (08-11-2020)“…( ) is a Gram-negative bacterium colonizing the human stomach. Nuclear Magnetic Resonance (NMR) analysis of intracellular human gastric carcinoma cells…”
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Persistent Endothelial Dysfunction in Post-Acute COVID-19 Syndrome: A Case-Control Study
Published in Biomedicines (04-08-2021)“…Background: Endothelial dysfunction has a key role in the pathogenesis of coronavirus disease 2019 (COVID-19) and its disabling complications. We designed a…”
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Enhancement of hepatic autophagy increases ureagenesis and protects against hyperammonemia
Published in Proceedings of the National Academy of Sciences - PNAS (09-01-2018)“…Ammonia is a potent neurotoxin that is detoxified mainly by the urea cycle in the liver. Hyperammonemia is a common complication of a wide variety of both…”
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Electronic Nose and Exhaled Breath NMR-based Metabolomics Applications in Airways Disease
Published in Current topics in medicinal chemistry (01-06-2016)“…Breathomics, the multidimensional molecular analysis of exhaled breath, includes analysis of exhaled breath with gas-chromatography/mass spectrometry (GC/MS)…”
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Performance of fractional exhaled nitric oxide in predicting response to inhaled corticosteroids in chronic cough: a meta-analysis
Published in Annals of medicine (Helsinki) (01-01-2021)“…Background. Chronic cough is a disabling condition with a high proportion of diagnostic and therapeutic failures. Fractional exhaled nitric oxide (FeNO) has…”
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NMR Profiling of Exhaled Breath Condensate Defines Different Metabolic Phenotypes of Non-Cystic Fibrosis Bronchiectasis
Published in International journal of molecular sciences (14-11-2020)“…Nuclear-magnetic-resonance (NMR) profiling of exhaled breath condensate (EBC) provides insights into the pathophysiology of bronchiectasis by identifying…”
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Effects of motor cortex modulation and descending inhibitory systems on pain thresholds in healthy subjects
Published in The journal of pain (01-05-2012)“…Pain modulation can be achieved using neuromodulatory tools that influence various levels of the nervous system. Transcranial direct current stimulation…”
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Mechanisms and Clinical Implications of Endothelial Dysfunction in Arterial Hypertension
Published in Journal of cardiovascular development and disease (27-04-2022)“…The endothelium is composed of a monolayer of endothelial cells, lining the interior surface of blood and lymphatic vessels. Endothelial cells display…”
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Fractional Exhaled Nitric Oxide (FENO) in the management of asthma: a position paper of the Italian Respiratory Society (SIP/IRS) and Italian Society of Allergy, Asthma and Clinical Immunology (SIAAIC)
Published in Multidisciplinary respiratory medicine (19-02-2020)“…Asthma prevalence in Italy is on the rise and is estimated to be over 6% of the general population. The diagnosis of asthma can be challenging and elusive,…”
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O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis
Published in Nature communications (05-09-2022)“…Life-threatening hyperammonemia occurs in both inherited and acquired liver diseases affecting ureagenesis, the main pathway for detoxification of neurotoxic…”
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Plant Dynamic Metabolic Response to Bacteriophage Treatment After Xanthomonas campestris pv. campestris Infection
Published in Frontiers in microbiology (22-04-2020)“…Periodic epidemics of black rot disease occur worldwide causing substantial yield losses. pv. ( ) represents one of the most common bacteria able to cause the…”
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Monitoring Real-Time Metabolism of Living Cells by Fast Two-Dimensional NMR Spectroscopy
Published in Analytical chemistry (Washington) (15-03-2010)“…Living cell metabolism is often monitored by 1D NMR spectroscopy, but the spectral resolution and the short cell lifetime are certainly limiting aspects. 2D…”
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