Search Results - "MOTOI, Fuyuhiko"
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Adjuvant and neoadjuvant treatment for pancreatic adenocarcinoma
Published in Japanese journal of clinical oncology (05-05-2020)“…The prognosis of pancreatic adenocarcinoma is dismal. Hence, advances in multidisciplinary treatment strategies, including surgery, are urgently needed. Early…”
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Randomized phase II/III trial of neoadjuvant chemotherapy with gemcitabine and S-1 versus upfront surgery for resectable pancreatic cancer (Prep-02/JSAP05)
Published in Japanese journal of clinical oncology (01-02-2019)“…A randomized, controlled trial has begun to compare neoadjuvant chemotherapy using gemcitabine and S-1 with upfront surgery for patients planned resection of…”
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Long-term outcome following neoadjuvant therapy for resectable and borderline resectable pancreatic cancer compared to upfront surgery: a meta-analysis of comparative studies by intention-to-treat analysis
Published in Surgery today (Tokyo, Japan) (01-04-2019)“…The aim of the study was to evaluate the effect of neoadjuvant therapy on long-term survival in patients with resectable and borderline resectable pancreatic…”
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Neoadjuvant treatment for resectable pancreatic adenocarcinoma: What is the best protocol?
Published in Annals of gastroenterological surgery (01-03-2020)“…Although upfront surgery has been the gold standard for pancreatic adenocarcinoma that is planned for resection, it should be compared with the alternative…”
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Risk factors of serious postoperative complications after pancreaticoduodenectomy and risk calculators for predicting postoperative complications: a nationwide study of 17,564 patients in Japan
Published in Journal of hepato-biliary-pancreatic sciences (01-05-2017)“…Background The morbidity rate after pancreaticoduodenectomy remains high. The objectives of this retrospective cohort study were to clarify the risk factors…”
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Pathways for the development of multiple epithelial types of intraductal papillary mucinous neoplasm of the pancreas
Published in Journal of gastroenterology (01-06-2021)“…Background Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is categorized into four distinct types: the gastric, intestinal, pancreatobiliary,…”
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Prognostic impact of postoperative circulating tumor DNA as a molecular minimal residual disease marker in patients with pancreatic cancer undergoing surgical resection
Published in Journal of hepato-biliary-pancreatic sciences (01-06-2023)“…Purpose We aimed to clarify the prognostic impact of postoperative circulating tumor DNA (ctDNA) shortly after pancreatectomy in patients with pancreatic…”
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A single-arm, phase II trial of neoadjuvant gemcitabine and S1 in patients with resectable and borderline resectable pancreatic adenocarcinoma: PREP-01 study
Published in Journal of gastroenterology (01-02-2019)“…Background Neoadjuvant chemotherapy (NAC) represents a promising alternative to pancreatic ductal adenocarcinoma (PDAC) planned resection, but the survival…”
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Association between Serum Magnesium Levels and Mortality in a Community-Based Population: The Yamagata (Takahata) Study
Published in Journal of Nutritional Science and Vitaminology (31-08-2022)“…The element magnesium (Mg) is involved in various metabolic reactions within the human body, and its deficiency is considered a risk factor for several…”
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Staging laparoscopy is mandatory for the treatment of pancreatic cancer to avoid missing radiologically negative metastases
Published in Surgery today (Tokyo, Japan) (01-05-2021)“…Purpose Staging laparoscopy is considered useful for determining treatment plans for advanced pancreatic cancer. However, the indications for staging…”
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Circulating tumor DNA as a predictive marker for occult metastases in pancreatic cancer patients with radiographically non‐metastatic disease
Published in Journal of hepato-biliary-pancreatic sciences (01-08-2021)“…Purpose To elucidate the effectiveness of circulating tumor DNA (ctDNA) for predicting occult metastases in patients with pancreatic cancer without apparent…”
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Mechanism of Bile Acid Reabsorption in the Biliopancreatic Limb After Duodenal-Jejunal Bypass in Rats
Published in Obesity surgery (01-07-2020)“…Background Bile acids (BAs) are important in the metabolic effects of bariatric surgery. Most BAs are reabsorbed in the ileum and recycled back to the liver…”
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Methylation-mediated silencing of the LIM homeobox 6 (LHX6) gene promotes cell proliferation in human pancreatic cancer
Published in Biochemical and biophysical research communications (04-06-2020)“…Epigenetic gene silencing by aberrant DNA methylation leads to loss of key cellular pathways in tumorigenesis. DNA methylation-mediated silenced genes in…”
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Increased Bile Acid Signals After Duodenal-Jejunal Bypass Improve Non-alcoholic Steatohepatitis (NASH) in a Rodent Model of Diet-Induced NASH
Published in Obesity surgery (01-06-2018)“…Background The increasing incidence of non-alcoholic steatohepatitis (NASH) has resulted in it becoming a common cause of liver-related mortality; however, no…”
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Early postoperative drainage fluid culture positivity from contaminated bile juice is predictive of pancreatic fistula after pancreaticoduodenectomy
Published in Surgery today (Tokyo, Japan) (01-03-2020)“…Purpose To investigate the impact of early postoperative drainage fluid culture positivity on the development of clinically relevant postoperative pancreatic…”
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Quantitative digital image analysis of somatostatin receptor 2 immunohistochemistry in pancreatic neuroendocrine tumors
Published in Medical molecular morphology (01-12-2021)“…Immunohistochemical analysis of somatostatin receptor 2 (SSTR2) provides important information regarding the potential therapeutic efficacy of somatostatin…”
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Serine/Threonine Kinase 11 Plays a Canonical Role in Malignant Progression of KRAS -Mutant and GNAS -Wild-Type Intraductal Papillary Mucinous Neoplasms of the Pancreas
Published in Annals of surgery (01-02-2023)“…We aimed to elucidate the clinicopathobiological significance of Serine/Threonine Kinase 11 (STK11) in pancreatic intraductal papillary mucinous neoplasms…”
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Kindlin-2 in pancreatic stellate cells promotes the progression of pancreatic cancer
Published in Cancer letters (01-04-2017)“…Abstract Pancreatic stellate cells (PSCs) play a pivotal role in pancreatic fibrosis associated with pancreatic ductal adenocarcinoma (PDAC). Kindlin-2 is a…”
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