Search Results - "MOSTOWSKI, Howard S"

CXCL16 Influences the Nature and Specificity of CpG-Induced Immune Activation by Gursel, Mayda, Gursel, Ihsan, Mostowski, Howard S, Klinman, Dennis M

“…Unmethylated CpG motifs are present at high frequency in bacterial DNA. They provide a danger signal to the mammalian immune system that triggers a protective…”
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Identification of Linear Heparin-Binding Peptides Derived from Human Respiratory Syncytial Virus Fusion Glycoprotein That Inhibit Infectivity by CRIM, Roberta L, AUDET, Susette A, FELDMAN, Steven A, MOSTOWSKI, Howard S, BEELER, Judy A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Isolation of a circulating CD45-, CD34dim cell population and validation of their endothelial phenotype by Tropea, Margaret M, Harper, Bonnie J A, Graninger, Grace M, Phillips, Terry M, Ferreyra, Gabriela, Mostowski, Howard S, Danner, Robert L, Suffredini, Anthony F, Solomon, Michael A

“…Accurately detecting circulating endothelial cells (CECs) is important since their enumeration has been proposed as a biomarker to measure injury to the…”
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Production of IL-10 by Human Natural Killer Cells Stimulated with IL-2 and/or IL-12 by Mehrotra, Priti T, Donnelly, Raymond P, Wong, Susan, Kanegane, Hirokazu, Geremew, Amare, Mostowski, Howard S, Furuke, Keizo, Siegel, Jay P, Bloom, Eda T

“…Human NK cell activity can be augmented in vitro by stimulation with IL-2 or IL-12, both of which also induce the production of IFN-gamma, TNF-alpha, and…”
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Fas Ligand Induction in Human NK Cells Is Regulated by Redox Through a Calcineurin-Nuclear Factors of Activated T Cell-Dependent Pathway by Furuke, Keizo, Shiraishi, Mitsuhiro, Mostowski, Howard S, Bloom, Eda T

“…Fas ligand (FasL) on cytotoxic lymphocytes is important for mediating apoptosis of activated lymphocytes and other target cells. We have reported that NK cell…”
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Regulatory T cells as central regulators of both autoimmunity and B cell malignancy in New Zealand Black mice by Scaglione, Brian J, Salerno, Erica, Gala, Kinisha, Pan, Manjing, Langer, Jerome A, Mostowski, Howard S, Bauer, Steven, Marti, Gerald, Li, Yu, Tsiagbe, Vincent K, Raveche, Elizabeth S

“…Abstract Regulatory T cells (Tregs) play an important role in protection against autoimmune disease and are also known to be potent inhibitors of anti-tumor…”
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Expression of a Constitutive Mutant of Iron Regulatory Protein 1 Abolishes Iron Homeostasis in Mammalian Cells (∗) by DeRusso, Patricia A., Philpott, Caroline C., Iwai, Kazuhiro, Mostowski, Howard S., Klausner, Richard D., Rouault, Tracey A.

“…Iron regulatory proteins (IRPs) are iron-sensing proteins that bind to RNA stem-loop sequences known as iron-responsive elements (IREs) when cells are depleted…”
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IL-12 administered in vivo to young and aged mice. Discrepancy between the effects on tumor growth in vivo and cytotoxic T lymphocyte generation ex vivo: Dependence on (IFN-gamma) by Horvath-Arcidiacono, Judith A, Mostowski, Howard S, Bloom, Eda T

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Effects of IL-12 on the generation of cytotoxic activity in human CD8+ T lymphocytes by Mehrotra, PT, Wu, D, Crim, JA, Mostowski, HS, Siegel, JP

“…We have studied the effects of human rIL-12 on the proliferation and generation of cytotoxic activity in human CTL precursors. Purified human blood CD8+ T…”
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Underutilization of the Vκ10C Gene in the B Cell Repertoire Is Due to the Loss of Productive VJ Rearrangements During B Cell Development by Fitzsimmons, Sean P., Clark, Kathleen J., Mostowski, Howard S., Shapiro, Marjorie A.

“…The Vκ10 family of murine light chain Ig genes is composed of three members, two of which (Vκ10A and Vκ10B) are well used. Vκ10C, the third member of this…”
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Target Cell-Induced Apoptosis of Interleukin-2–Activated Human Natural Killer Cells: Roles of Cell Surface Molecules and Intracellular Events by Yamauchi, Akira, Taga, Kazuyuki, Mostowski, Howard S., Bloom, Eda T.

“…We previously reported that natural killer (NK)-sensitive target cells, K562, kill interleukin-2-stimulated (lymphokine-activated killer [LAK]) but not…”
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Cytokine-induced enhancement of ICAM-1 expression results in increased vulnerability of tumor cells to monocyte-mediated lysis by Webb, DS, Mostowski, HS, Gerrard, TL

“…Pretreatment of the human melanoma cell line, A375, and the human colon carcinoma cell line, HT-29, with certain cytokines was found to increase the…”
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Regulation of human cytotoxic T lymphocyte development by IL-7 by Hickman, CJ, Crim, JA, Mostowski, HS, Siegel, JP

“…The effects of IL-7 on the generation of human CTL in alloantigen-, virus-, and lectin-stimulated systems were examined. Addition of IL-7 at the onset of…”
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IL-4 and granulocyte-macrophage colony-stimulating factor selectively increase HLA-DR and HLA-DP antigens but not HLA-DQ antigens on human monocytes by Gerrard, TL, Dyer, DR, Mostowski, HS

“…A number of cytokines were tested for their ability to modulate HLA-DR Ag expression on normal human monocytes. IL-4, granulocyte-macrophage (GM)-CSF as well…”
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Mitogenic stimulation of human lymphocytes mediated by a cell surface elastase by Packard, Beverly Z., Mostowski, Howard S., Komoriya, Akira

“…A ca. 45-kDa protein which was recently identified and purified to homogeneity from a solid tumor cell line as a T-cell mitogen was found to have significant…”
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A bioassay for the measurement of human interleukin-4 by Siegel, J P, Mostowski, H S

“…We have developed a bioassay for human IL-4 based upon its ability to upregulate CD23 (low affinity IgE receptor) expression. Ramos, a B lymphocyte line…”
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IL-12 administered in vivo to young and aged mice. Discrepancy between the effects on tumor growth in vivo and cytotoxic T lymphocyte generation ex vivo: dependence on IFN-γ by Horvath-Arcidiacono, Judith A., Mostowski, Howard S., Bloom, Eda T.

“…Because IL-12 restores allogeneic cytotoxic T lymphocyte (CTL) activity by T cells of aged mice in vitro, we initially assessed whether IL-12 could overcome…”
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Re-evaluation of the involvement of the adhesion molecules ICAM-1/LFA-1 in syncytia formation of HIV-1-infected subclones of a CEM T-cell leukemic line by Gruber, M F, Webb, D S, Gerrard, T L, Mostowski, H S, Vujcic, L, Golding, H

“…The role of the adhesion molecules intercellular adhesion molecule-1 (ICAM-1) and LFA-1 in human immunodeficiency virus type 1 (HIV-1)-induced cell fusion was…”
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Pore-forming protein in individual cytotoxic T lymphocytes: the effect of senescence provides a probe for understanding the lytic mechanism by Horvath, J A, Mostowski, H S, Okumura, K, Bloom, E T

“…The senescent decline of cytolytic T lymphocyte (CTL) activity was examined (a) to learn more about the effect of aging on the immune system, and (b) to probe…”
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Underutilization of the V{kappa}10C Gene in the B Cell Repertoire Is Due to the Loss of Productive VJ Rearrangements During B Cell Development by Fitzsimmons, Sean P, Clark, Kathleen J, Mostowski, Howard S, Shapiro, Marjorie A

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