Search Results - "MOSKALUK, C. A"

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior by Ivanov, S V, Panaccione, A, Brown, B, Guo, Y, Moskaluk, C A, Wick, M J, Brown, J L, Ivanova, A V, Issaeva, N, El-Naggar, A K, Yarbrough, W G

“…Treatment options for adenoid cystic carcinoma (ACC) of the salivary gland, a slowly growing tumor with propensity for neuroinvasion and late recurrence, are…”
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Knockdown of Sox4 expression by RNAi induces apoptosis in ACC3 cells by PRAMOONJAGO, P, BARAS, A. S, MOSKALUK, C. A

“…Microarray RNA gene expression profiling analysis has shown that Sox4 (Sry-related high mobility group (HMG) box 4) is one of the most upregulated genes in…”
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Combined genomic and gene expression microarray profiling identifies ECOP as an upregulated gene in squamous cell carcinomas independent of DNA amplification by Baras, A, Yu, Y, Filtz, M, Kim, B, Moskaluk, C A

“…To identify dysregulated genes that may play a role in the pathogenesis of tobacco-related human squamous cell carcinoma (SCC), a cohort of SCCs from smokers…”
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Establishing a tumour bank: banking, informatics and ethics by QUALMAN, S. J, FRANCE, M, GRIZZLE, W. E, LIVOLSI, V. A, MOSKALUK, C. A, RAMIREZ, N. C, WASHINGTON, M. K

“…The six divisions of the Cooperative Human Tissue Network in the USA bank and distribute tens of thousands of tissue specimens to researchers annually. Major…”
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Activating c-kit Gene Mutations in Human Germ Cell Tumors by Tian, Qingsheng, Frierson, Henry F., Krystal, Geoffrey W., Moskaluk, Christopher A.

“…The c-kit gene encodes a tyrosine kinase receptor (KIT) that is required in normal spermatogenesis and is expressed in seminomas and dysgerminomas, a subset of…”
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Microdissection and polymerase chain reaction amplification of genomic DNA from histological tissue sections by Moskaluk, CA, Kern, SE

“…Polymerase chain reaction (PCR)-based assays are being used increasingly to study the molecular genetic changes that occur in minute cellular lesions that are…”
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Mutations of c-kit JM domain are found in a minority of human gastrointestinal stromal tumors by MOSKALUK, C. A, TIAN, Q, MARSHALL, C. R, RUMPEL, C. A, FRANQUEMONT, D. W, FRIERSON, H. F

“…The c-kit gene encodes a transmembrane receptor kinase (KIT) which is expressed in the majority of human gastrointestinal stromal tumors (GISTs), a subtype of…”
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p16 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma by MOSKALUK, C. A, HRUBAN, R. H, KERN, S. E

“…Pancreatic adenocarcinoma is thought to arise from a noninvasive neoplastic precursor, the pancreatic intraductal lesion (PIL). Mutations of the K-ras gene are…”
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The effects of frozen tissue storage conditions on the integrity of RNA and protein by Auer, H, Mobley, J A, Ayers, L W, Bowen, J, Chuaqui, R F, Johnson, L A, Livolsi, V A, Lubensky, I A, McGarvey, D, Monovich, L C, Moskaluk, C A, Rumpel, C A, Sexton, K C, Washington, M K, Wiles, K R, Grizzle, W E, Ramirez, N C

“…Unfixed tissue specimens most frequently are stored for long term research uses at either -80° C or in vapor phase liquid nitrogen (VPLN). There is little…”
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Overexpression of CEBPβ correlates with decreased TFF1 in gastric cancer by SANKPAL, N. V, MOSKALUK, C. A, HAMPTON, G. M, POWELL, S. M

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DPC4, A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1 by Hahn, Stephan A., Schutte, Mieke, A. T. M. Shamsul Hoque, Moskaluk, Christopher A., da Costa, Luis T., Rozenblum, Ester, Weinstein, Craig L., Fischer, Aryeh, Yeo, Charles J., Hruban, Ralph H., Kern, Scott E.

“…About 90 percent of human pancreatic carcinomas show allelic loss at chromosome 18q. To identify candidate tumor suppressor genes on 18q, a panel of pancreatic…”
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Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas by SCHUTTE, M, HRUBAN, R. H, BAYLIN, S. B, KERN, S. E, HERMAN, J. G, GERADTS, J, MAYNARD, R, HILGERS, W, RABINDRAN, S. K, MOSKALUK, C. A, HAHN, S. A, SCHWARTE-WALDHOFF, I, SCHMIEGEL, W

“…The Rb/p16 tumor-suppressive pathway is abrogated frequently in human tumors, either through inactivation of the Rb or p16INK4a/CDKN2/MTS1 tumor-suppressor…”
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Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas by GOGGINS, M, SCHUTTE, M, KERN, S. E, LU, J, MOSKALUK, C. A, WEINSTEIN, C. L, PETERSEN, G. M, YEO, C. J, JACKSON, C. E, LYNCH, H. T, HRUBAN, R. H

“…Germline mutations in BRCA2 predispose carriers to the development of breast, ovarian, and a variety of other cancers. The original localization of the BRCA2…”
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The multiple endocrine neoplasia type I gene locus is involved in the pathogenesis of type II gastric carcinoids by Debelenko, LV, Emmert-Buck, MR, Zhuang, Z, Epshteyn, E, Moskaluk, CA, Jensen, RT, Liotta, LA, Lubensky, IA

“…BACKGROUND & AIMS: Both gastrin and genetic factors were suggested to underlie the pathogenesis of multiple gastric enterochromaffin-like (ECL) cell…”
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Homozygous deletion map at 18q21.1 in pancreatic cancer by HAHN, S. A, HOQUE, A. T. M. S, KERN, S. E, MOSKALUK, C. A, DA COSTA, L. T, SCHUTTE, M, ROZENBLUM, E, SEYMOUR, A. B, WEINSTEIN, C. L, YEO, C. J, HRUBAN, R. H

“…Absolute genetic differences between neoplastic and nonneoplastic cells can be discerned at sites of homozygous deletions. These deletions are of critical…”
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Origin of Microsatellite Instability in Gastric Cancer by Halling, Kevin C., Harper, Jeffrey, Moskaluk, Christopher A., Thibodeau, Stephen N., Petroni, Gina R., Yustein, Aron S., Tosi, Piero, Minacci, Chiara, Roviello, Franco, Piva, Paolo, Hamilton, Stanley R., Jackson, Charles E., Powell, Steven M.

“…Microsatellite instability (MSI) is observed in 13–44% of gastric carcinoma. The etiology of MSI in gastric carcinoma has not been clearly defined. To assess…”
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PAC-1: A Mitogen-Induced Nuclear Protein Tyrosine Phosphatase by Rohan, Patricia J., Davis, Paula, Moskaluk, Christopher A., Kearns, Mary, Krutzsch, Henry, Siebenlist, Ulrich, Kelly, Kathleen

“…Tyrosine phosphorylation of proteins is required for signal transduction in cells and for growth regulation. A mitogen-induced gene (PAC-1) has been cloned…”
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Allelotype of gastric adenocarcinoma by YUSTEIN, A. S, HARPER, J. C, PETRONI, G. R, CUMMINGS, O. W, MOSKALUK, C. A, POWELL, S. M

“…Gastric adenocarcinoma is a leading cause of cancer mortality world-wide. Yet, the underlying molecular events important in the development of this cancer are…”
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Genetic alterations and epithelial dysplasia in juvenile polyposis syndrome and sporadic juvenile polyps by Wu, TT, Rezai, B, Rashid, A, Luce, MC, Cayouette, MC, Kim, C, Sani, N, Mishra, L, Moskaluk, CA, Yardley, JH, Hamilton, SR

“…Juvenile polyps are regarded as hamartomatous polyps and occur in sporadic and familial syndromic settings. There is increased risk of gastrointestinal…”
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Mapping of Genetic Deletions on the Long Arm of Chromosome 4 in Human Esophageal Adenocarcinomas by Rumpel, Craig A., Powell, Steven M., Moskaluk, Christopher A.

“…Loss of the long arm of chromosome 4 has been identified previously as a common occurrence in adenocarcinomas of the esophagus and gastroesophageal junction by…”
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