Search Results - "MOSES, E. K"

Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes by Carless, M A, Glahn, D C, Johnson, M P, Curran, J E, Bozaoglu, K, Dyer, T D, Winkler, A M, Cole, S A, Almasy, L, MacCluer, J W, Duggirala, R, Moses, E K, Göring, H H H, Blangero, J

“…Although disrupted in schizophrenia 1 ( DISC1 ) has been implicated in many psychiatric disorders, including schizophrenia, bipolar disorder, schizoaffective…”
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Increased endoplasmic reticulum stress in decidual tissue from pregnancies complicated by fetal growth restriction with and without pre-eclampsia by Lian, I.A, Løset, M, Mundal, S.B, Fenstad, M.H, Johnson, M.P, Eide, I.P, Bjørge, L, Freed, K.A, Moses, E.K, Austgulen, R

“…Abstract Objectives Endoplasmic reticulum (ER) stress has been implicated in both pre-eclampsia (PE) and fetal growth restriction (FGR), and is characterised…”
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A low COMT activity haplotype is associated with recurrent preeclampsia in a Norwegian population cohort (HUNT2) by Roten, L.T., Fenstad, M.H., Forsmo, S., Johnson, M.P., Moses, E.K., Austgulen, R., Skorpen, F.

“…The etiology of preeclampsia is complex, with susceptibility being attributable to multiple environmental factors and a large genetic component. Although many…”
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Transcriptomics of cortical gray matter thickness decline during normal aging by Kochunov, P., Charlesworth, J., Winkler, A., Hong, L.E., Nichols, T.E., Curran, J.E., Sprooten, E., Jahanshad, N., Thompson, P.M., Johnson, M.P., Kent, J.W., Landman, B.A., Mitchell, B., Cole, S.A., Dyer, T.D., Moses, E.K., Goring, H.H.H., Almasy, L., Duggirala, R., Olvera, R.L., Glahn, D.C., Blangero, J.

“…We performed a whole-transcriptome correlation analysis, followed by the pathway enrichment and testing of innate immune response pathway analyses to evaluate…”
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The association of host and genetic melanoma risk factors with Breslow thickness in the Western Australian Melanoma Health Study by Cadby, G., Ward, S.V., Cole, J.M., Moses, E.K., Millward, M., Palmer, L.J.

“…Summary Background Breslow thickness is the most important predictor of survival in localized malignant melanoma. A number of melanoma risk factors have been…”
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INSIG1 influences obesity-related hypertriglyceridemia in humans by Smith, E.M., Zhang, Y., Baye, T. M, Gawrieh, S., Cole, R., Blangero, J., Carless, M.A., Curran, J.E., Dyer, T.D., Abraham, L.J., Moses, E.K., Kissebah, A.H., Martin, L.J., Olivier, M.

“…In our analysis of a quantitative trait locus (QTL) for plasma triglyceride (TG) levels [logarithm of odds (LOD) = 3.7] on human chromosome 7q36, we examined…”
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Genetic association of the activin A receptor gene (ACVR2A) and pre-eclampsia by Fitzpatrick, E., Johnson, M.P., Dyer, T.D., Forrest, S., Elliott, K., Blangero, J., Brennecke, S.P., Moses, E.K.

“…Pre-eclampsia is a common serious disorder of human pregnancy, which is associated with significant maternal and perinatal morbidity and mortality. The…”
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Genetical genomics of Th1 and Th2 immune response in a baboon model of atherosclerosis risk factors by Vinson, A, Curran, J.E, Johnson, M.P, Dyer, T.D, Moses, E.K, Blangero, J, Cox, L.A, Rogers, J, Havill, L.M, VandeBerg, J.L, Mahaney, M.C

“…Abstract Objective CD4+ T-cells mediate inflammation in atherosclerosis, but additive genetic effects on associated pathways of Th1 and Th2 immune response…”
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Objective prioritization of positional candidate genes at a quantitative trait locus for pre-eclampsia on 2q22 by Moses, E.K., Fitzpatrick, E., Freed, K.A., Dyer, T.D., Forrest, S., Elliott, K., Johnson, M.P., Blangero, J., Brennecke, S.P.

“…Pre-eclampsia/eclampsia (PE/E) is a common, serious medical disorder of human pregnancy. Familial association of PE/E has been recognized for decades, but the…”
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Identification of two novel quantitative trait loci for pre-eclampsia susceptibility on chromosomes 5q and 13q using a variance components-based linkage approach by Johnson, M.P., Fitzpatrick, E., Dyer, T.D., Jowett, J.B.M., Brennecke, S.P., Blangero, J., Moses, E.K.

“…Pre-eclampsia/eclampsia (PE/E) is a common and serious disorder of human pregnancy that is associated with substantial maternal and perinatal morbidity and…”
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Localization of a major susceptibility locus influencing preterm birth by Chittoor, G, Farook, V S, Puppala, S, Fowler, S P, Schneider, J, Dyer, T D, Cole, S A, Lynch, J L, Curran, J E, Almasy, L, Maccluer, J W, Comuzzie, A G, Hale, D E, Ramamurthy, R S, Dudley, D J, Moses, E K, Arya, R, Lehman, D M, Jenkinson, C P, Bradshaw, B S, Defronzo, R A, Blangero, J, Duggirala, R

“…Preterm birth (PTB) is a complex trait, but little is known regarding its major genetic determinants. The objective of this study is to localize genes that…”
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Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels by Zhang, Y, Smith, E M, Baye, T M, Eckert, J V, Abraham, L J, Moses, E K, Kissebah, A H, Martin, L J, Olivier, M

“…Neurotransmitters such as serotonin (5-hydroxytryptamine, 5-HT) work closely with leptin and insulin to fine-tune the metabolic and neuroendocrine responses to…”
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Differential DNA methylation of steatosis and non-alcoholic fatty liver disease in adolescence by Melton, Phillip E., Burton, M. A., Lillycrop, K. A., Godfrey, K. M., Rauschert, S., Anderson, D., Burdge, G. C., Mori, T. A., Beilin, L. J., Ayonrinde, O. T., Craig, J. M., Olynyk, J. K., Holbrook, J. D., Pennell, C. E., Oddy, W. H., Moses, E. K., Adams, L. A., Huang, R. C.

“…Background and aims Epigenetic modifications are associated with hepatic fat accumulation and non-alcoholic fatty liver disease (NAFLD). However, few…”
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A Genome Scan in Families from Australia and New Zealand Confirms the Presence of a Maternal Susceptibility Locus for Pre-Eclampsia, on Chromosome 2 by Moses, Eric K., Lade, Jennifer A., Guo, Guanglan, Wilton, Alan N., Grehan, Madonna, Freed, Katy, Borg, Anthony, Terwilliger, Joseph D., North, Robyn, Cooper, Desmond W., Brennecke, Shaun P.

“…Epidemiological studies have shown that genetic factors contribute to the etiology of the common and serious pregnancy-specific disorder pre-eclampsia…”
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Fine Mapping and SNP Analysis of Positional Candidates at the Preeclampsia Susceptibility Locus (PREG1) on Chromosome 2 by FITZPATRICK, E., GÖRING, H.H.H., LIU, H., BORG, A., FORREST, S., COOPER, D.W., BRENNECKE, S.P., MOSES, E.K.

“…Genome scans in Icelandic, Australian and New Zealand, and Finnish families have localized putative susceptibility loci for preeclampsia/eclampsia to…”
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Increased decidual mRNA expression levels of candidate maternal preeclampsia susceptibility genes are associated with clinical severity by YANG, H. E. J, MURTHI, P, BORG, A, KALIONIS, B, MOSES, E. K, BRENNECKE, S. P, KEOGH, R. J

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Detection of CAG repeats in pre-eclampsia/eclampsia using the repeat expansion detection method by Freed, K.A., Cooper, D.W., Brennecke, S.P., Moses, E.K.

“…Pre-eclampsia/eclampsia is a serious disorder of human pregnancy that has a worldwide incidence of 2–10% and carries a severe morbidity and mortality risk for…”
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Gene expression of the constant region of the heavy chain of immunoglobulin G (IgG CRHC) is down-regulated in human decidua in association with preeclampsia by Freed, K.A., Brennecke, S.P., Moses, E.K.

“…An aberrant interaction at the maternal/fetal interface between the genetically distinct fetal trophoblast cells and cells of the maternal decidua has been…”
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Increased decidual mRNA expression levels of candidate maternal pre-eclampsia susceptibility genes are associated with clinical severity by Yong, H.E.J, Murthi, P, Borg, A, Kalionis, B, Moses, E.K, Brennecke, S.P, Keogh, R.J

“…Abstract Introduction Pre-eclampsia (PE) has a familial association, with daughters of women who had PE during pregnancy having more than twice the risk of…”
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Differential mRNA Expression of Urokinase-Type Plasminogen Activator, Plasminogen Activator Receptor and Plasminogen Activator Inhibitor Type-2 in Normal Human Endometria and Endometrial Carcinomas by Foca, C., Moses, E.K., Quinn, M.A., Rice, G.E.

“…Objective. Extracellular proteolytic degradation is an essential part of cellular invasive processes. The increased proteolytic activity observed in invasive…”
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