Search Results - "MOSES, Ashlee V"

IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling by Lazear, Helen M, Lancaster, Alissa, Wilkins, Courtney, Suthar, Mehul S, Huang, Albert, Vick, Sarah C, Clepper, Lisa, Thackray, Larissa, Brassil, Margaret M, Virgin, Herbert W, Nikolich-Zugich, Janko, Moses, Ashlee V, Gale, Jr, Michael, Früh, Klaus, Diamond, Michael S

“…Although the transcription factors IRF-3 and IRF-7 are considered master regulators of type I interferon (IFN) induction and IFN stimulated gene (ISG)…”
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Comparative study of four immortalized human brain capillary endothelial cell lines, hCMEC/D3, hBMEC, TY10, and BB19, and optimization of culture conditions, for an in vitro blood-brain barrier model for drug permeability studies by Eigenmann, Daniela E, Xue, Gongda, Kim, Kwang S, Moses, Ashlee V, Hamburger, Matthias, Oufir, Mouhssin

“…Reliable human in vitro blood-brain barrier (BBB) models suitable for high-throughput screening are urgently needed in early drug discovery and development for…”
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Vpu Directs the Degradation of the Human Immunodeficiency Virus Restriction Factor BST-2/Tetherin via a βTrCP-Dependent Mechanism by DOUGLAS, Janet L, VISWANATHAN, Kasinath, MCCARROLL, Matthew N, GUSTIN, Jean K, FRÜH, Klaus, MOSES, Ashlee V

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Molecular Mechanism of BST2/Tetherin Downregulation by K5/MIR2 of Kaposi's Sarcoma-Associated Herpesvirus by MANSOURI, Mandana, VISWANATHAN, Kasinath, DOUGLAS, Janet L, HINES, Jennie, GUSTIN, Jean, MOSES, Ashlee V, FRÜH, Klaus

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The great escape: viral strategies to counter BST-2/tetherin by Douglas, Janet L, Gustin, Jean K, Viswanathan, Kasinath, Mansouri, Mandana, Moses, Ashlee V, Früh, Klaus

“…The interferon-induced BST-2 protein has the unique ability to restrict the egress of HIV-1, Kaposi's sarcoma-associated herpesvirus (KSHV), Ebola virus, and…”
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Full-Length Isoforms of Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Accumulate in the Cytoplasm of Cells Undergoing the Lytic Cycle of Replication by Garrigues, H Jacques, Howard, Kellie, Barcy, Serge, Ikoma, Minako, Moses, Ashlee V, Deutsch, Gail H, Wu, David, Ueda, Keiji, Rose, Timothy M

“…The latency-associated nuclear antigen (LANA) of the Kaposi's sarcoma-associated herpesvirus (KSHV) performs a variety of functions to establish and maintain…”
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Human Cytomegalovirus Secretome Contains Factors That Induce Angiogenesis and Wound Healing by DUMORTIER, Jerome, STREBLOW, Daniel N, MOSES, Ashlee V, JACOBS, Jon M, KREKLYWICH, Craig N, CAMP, David, SMITH, Richard D, ORLOFF, Susan L, NELSON, Jay A

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Remodeling of Endothelial Adherens Junctions by Kaposi's Sarcoma-Associated Herpesvirus by Mansouri, Mandana, Rose, Patrick P, Moses, Ashlee V, Früh, Klaus

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Aberrant proliferation in CXCR7+ endothelial cells via degradation of the retinoblastoma protein by Totonchy, Jennifer E, Osborn, Jessica M, Botto, Sara, Clepper, Lisa, Moses, Ashlee V

“…Angiogenesis is a critical factor in the growth and dissemination of solid tumors. Indeed, tumor vasculature is abnormal and contributes to the development and…”
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Viral takeover of the host ubiquitin system by Gustin, Jean K, Moses, Ashlee V, Früh, Klaus, Douglas, Janet L

“…Like the other more well-characterized post-translational modifications (phosphorylation, methylation, acetylation, acylation, etc.), the attachment of the 76…”
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Novel cellular genes essential for transformation of endothelial cells by Kaposi's sarcoma-associated herpesvirus by RAGGO, Camilo, RUHL, Rebecca, MCALLISTER, Shane, KOON, Henry, DEZUBE, Bruce J, FRÜH, Klaus, MOSES, Ashlee V

“…Kaposi's sarcoma-associated herpesvirus (KSHV) is involved in the development of lymphoproliferative diseases and Kaposi's sarcoma. The oncogenicity of this…”
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Kaposi sarcoma herpesvirus K5 removes CD31/PECAM from endothelial cells by Mansouri, Mandana, Douglas, Janet, Rose, Patrick P., Gouveia, Kristine, Thomas, Gary, Means, Robert E., Moses, Ashlee V., Früh, Klaus

“…The transmembrane ubiquitin ligase K5/MIR2 of Kaposi sarcoma herpesvirus (KSHV) mediates internalization and lysosomal degradation of glycoproteins involved in…”
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Blood-Brain Barrier Tight Junction Disruption in Human Immunodeficiency Virus-1 Encephalitis by Dallasta, Linda M., Pisarov, Liubomir A., Esplen, James E., Werley, Jonette V., Moses, Ashlee V., Nelson, Jay A., Achim, Cristian L.

“…The blood-brain barrier (BBB) plays a critical role in regulating cell trafficking through the central nervous system (CNS) due to several unique anatomical…”
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Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology by Hirsch, Alec J., Roberts, Victoria H. J., Grigsby, Peta L., Haese, Nicole, Schabel, Matthias C., Wang, Xiaojie, Lo, Jamie O., Liu, Zheng, Kroenke, Christopher D., Smith, Jessica L., Kelleher, Meredith, Broeckel, Rebecca, Kreklywich, Craig N., Parkins, Christopher J., Denton, Michael, Smith, Patricia, DeFilippis, Victor, Messer, William, Nelson, Jay A., Hennebold, Jon D., Grafe, Marjorie, Colgin, Lois, Lewis, Anne, Ducore, Rebecca, Swanson, Tonya, Legasse, Alfred W., Axthelm, Michael K., MacAllister, Rhonda, Moses, Ashlee V., Morgan, Terry K., Frias, Antonio E., Streblow, Daniel N.

“…Zika virus (ZIKV) infection during pregnancy leads to an increased risk of fetal growth restriction and fetal central nervous system malformations, which are…”
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Kaposi's Sarcoma-Associated Herpesvirus-Induced Upregulation of the c-kit Proto-Oncogene, as Identified by Gene Expression Profiling, Is Essential for the Transformation of Endothelial Cells by Moses, Ashlee V, Jarvis, Michael A, Raggo, Camilo, Bell, Yolanda C, Ruhl, Rebecca, Luukkonen, B G Mattias, Griffith, Diana J, Wait, Cecily L, Druker, Brian J, Heinrich, Michael C, Nelson, Jay A, Früh, Klaus

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Kaposi sarcoma-associated herpesvirus (KSHV) induces heme oxygenase-1 expression and activity in KSHV-infected endothelial cells by McAllister, Shane C., Hansen, Scott G., Ruhl, Rebecca A., Raggo, Camilo M., DeFilippis, Victor R., Greenspan, Deborah, Früh, Klaus, Moses, Ashlee V.

“…Kaposi sarcoma (KS) is the most common AIDS-associated malignancy and is characterized by angiogenesis and the presence of spindle cells. Kaposi…”
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Insulin-Like Growth Factor II Receptor-Mediated Intracellular Retention of Cathepsin B Is Essential for Transformation of Endothelial Cells by Kaposi's Sarcoma-Associated Herpesvirus by Rose, Patrick P, Bogyo, Matthew, Moses, Ashlee V, Früh, Klaus

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Ebola Virus Glycoprotein Promotes Enhanced Viral Egress by Preventing Ebola VP40 From Associating With the Host Restriction Factor BST2/Tetherin by Gustin, Jean K., Bai, Ying, Moses, Ashlee V., Douglas, Janet L.

“…Background. BST2/tetherin is an innate immune molecule with the unique ability to restrict the egress of human immunodeficiency virus (HIV) and other enveloped…”
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Kaposi's sarcoma and human dermal microvascular endothelial cells infected with Kaposi's sarcoma-associated herpesvirus express CCL21 by Sugaya, Makoto, Reed, Stacy, Rose, Patrick P, de la Motte, Stacy, Raggo, Camilo M, Kurtz, Stephen E, Moses, Ashlee V, Früh, Klaus, Blauvelt, Andrew

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The Heme Metabolite Carbon Monoxide Facilitates KSHV Infection by Inhibiting TLR4 Signaling in Endothelial Cells by Botto, Sara, Gustin, Jean K, Moses, Ashlee V

“…Kaposi sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi sarcoma (KS) and certain rare B cell lymphoproliferative disorders. KSHV infection of…”
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