Search Results - "MOSER, Patrizia L"

Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations by Moschen, Alexander R., Gerner, Romana R., Wang, Jun, Klepsch, Victoria, Adolph, Timon E., Reider, Simon J., Hackl, Hubert, Pfister, Alexandra, Schilling, Johannes, Moser, Patrizia L., Kempster, Sarah L., Swidsinski, Alexander, Orth−Höller, Dorothea, Weiss, Günter, Baines, John F., Kaser, Arthur, Tilg, Herbert

“…High mucosal and fecal concentrations of the antimicrobial siderophore-binding peptide Lipocalin-2 (Lcn2) are observed in inflammatory bowel disease. However,…”
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Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection by Nairz, Manfred, Schleicher, Ulrike, Schroll, Andrea, Sonnweber, Thomas, Theurl, Igor, Ludwiczek, Susanne, Talasz, Heribert, Brandacher, Gerald, Moser, Patrizia L, Muckenthaler, Martina U, Fang, Ferric C, Bogdan, Christian, Weiss, Günter

“…Nitric oxide (NO) generated by inducible NO synthase 2 (NOS2) affects cellular iron homeostasis, but the underlying molecular mechanisms and implications for…”
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Movember GAP1 PDX project: An international collection of serially transplantable prostate cancer patient‐derived xenograft (PDX) models by Navone, Nora M., van Weerden, Wytske M., Vessella, Robert L., Williams, Elizabeth D., Wang, Yuzhuo, Isaacs, John T., Nguyen, Holly M., Culig, Zoran, van der Pluijm, Gabri, Rentsch, Cyril A., Marques, Rute B., de Ridder, Corrina M. A., Bubendorf, Lukas, Thalmann, George N., Brennen, William Nathaniel, Santer, Frédéric R., Moser, Patrizia L., Shepherd, Peter, Efstathiou, Eleni, Xue, Hui, Lin, Dong, Buijs, Jeroen, Bosse, Tjalling, Collins, Anne, Maitland, Norman, Buzza, Mark, Kouspou, Michelle, Achtman, Ariel, Taylor, Renea A., Risbridger, Gail, Corey, Eva

“…Background While it has been challenging to establish prostate cancer patient‐derived xenografts (PDXs), with a take rate of 10‐40% and long latency time,…”
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Cell-specific expression of Hfe determines the outcome of Salmonella enterica serovar Typhimurium infection in mice by Nairz, Manfred, Metzendorf, Christoph, Vujic-Spasic, Maja, Mitterstiller, Anna-Maria, Schroll, Andrea, Haschka, David, Hoffmann, Alexander, Von Raffay, Laura, Sparla, Richard, Huck, Christian W, Talasz, Heribert, Moser, Patrizia L, Muckenthaler, Martina U, Weiss, Günter

“…Mutations in HFE cause hereditary hemochromatosis type I hallmarked by increased iron absorption, iron accumulation in hepatocytes and iron deficiency in…”
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The anti-interleukin-6 antibody siltuximab down-regulates genes implicated in tumorigenesis in prostate cancer patients from a phase I study by Karkera, Jayaprakash, Steiner, Hannes, Li, Weimin, Skradski, Viktor, Moser, Patrizia L., Riethdorf, Sabine, Reddy, Manjula, Puchalski, Thomas, Safer, Karim, Prabhakar, Uma, Pantel, Klaus, Qi, Ming, Culig, Zoran

“…BACKGROUND Interleukin‐6 (IL‐6) is associated with prostate cancer morbidity. In several experimental models, IL‐6 has been reported to have anti‐apoptotic and…”
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Lipocalin‐2 ensures host defense against Salmonella Typhimurium by controlling macrophage iron homeostasis and immune response by Nairz, Manfred, Schroll, Andrea, Haschka, David, Dichtl, Stefanie, Sonnweber, Thomas, Theurl, Igor, Theurl, Milan, Lindner, Ewald, Demetz, Egon, Aßhoff, Malte, Bellmann‐Weiler, Rosa, Müller, Raphael, Gerner, Romana R., Moschen, Alexander R., Baumgartner, Nadja, Moser, Patrizia L., Talasz, Heribert, Tilg, Herbert, Fang, Ferric C., Weiss, Günter

“…Lipocalin‐2 (Lcn2) is an innate immune peptide with pleiotropic effects. Lcn2 binds iron‐laden bacterial siderophores, chemo‐attracts neutrophils and has…”
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Baseline iron status and presence of anaemia determine the course of systemic Salmonella infection following oral iron supplementation in mice by Hoffmann, Alexander, Haschka, David, Valente de Souza, Lara, Tymoszuk, Piotr, Seifert, Markus, von Raffay, Laura, Hilbe, Richard, Petzer, Verena, Moser, Patrizia L, Nairz, Manfred, Weiss, Günter

“…[Display omitted] Iron deficiency anaemia (IDA) is a major health concern. However, preventive iron supplementation in regions with high burden of infectious…”
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Interleukin-6 stimulation of growth of prostate cancer in vitro and in vivo through activation of the androgen receptor by Malinowska, Kamilla, Neuwirt, Hannes, Cavarretta, Ilaria T, Bektic, Jasmin, Steiner, Hannes, Dietrich, Hermann, Moser, Patrizia L, Fuchs, Dietmar, Hobisch, Alfred, Culig, Zoran

“…It is hypothesized that ligand-independent activation of the androgen receptor is one of the mechanisms implicated in tumour progression. However, supportive…”
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Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis by Nairz, Manfred, Haschka, David, Dichtl, Stefanie, Sonnweber, Thomas, Schroll, Andrea, Aßhoff, Malte, Mindur, John E., Moser, Patrizia L., Wolf, Dominik, Swirski, Filip K., Theurl, Igor, Cerami, Anthony, Brines, Michael, Weiss, Günter

“…Two distinct forms of the erythropoietin receptor (EPOR) mediate the cellular responses to erythropoietin (EPO) in different tissues. EPOR homodimers signal to…”
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IL6 sensitizes prostate cancer to the antiproliferative effect of IFNα2 through IRF9 by Erb, Holger H H, Langlechner, Regina V, Moser, Patrizia L, Handle, Florian, Casneuf, Tineke, Verstraeten, Karin, Schlick, Bettina, Schäfer, Georg, Hall, Brett, Sasser, Kate, Culig, Zoran, Santer, Frédéric R

“…Development and progression of prostate cancer (PCa) are associated with chronic inflammation. The cytokine interleukin 6 (IL6) can influence progression,…”
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Endocardial fibroelastosis of the heart by Steger, Christina M, Dr, Antretter, Herwig, Prof, Moser, Patrizia L, Prof

“…The disease can be primary or secondary to various congenital heart diseases, most notably aortic stenosis or atresia, but also mitral incompetence,…”
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Increased activated Akt expression in renal cell carcinomas and prognosis by Hager, Martina, Haufe, Heike, Kemmerling, Ralf, Hitzl, Wolfgang, Mikuz, Gregor, Moser, Patrizia L., Kolbitsch, Christian

“…Renal carcinogenesis is promoted by overexpression of the activated serine/threonine kinase Akt (p‐Akt) and supposedly a concomitant reduction in phosphatase…”
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Normal values for thrombelastography (ROTEM®) and selected coagulation parameters in porcine blood by Velik-Salchner, Corinna, Schnürer, Christian, Fries, Dietmar, Müssigang, Peter R., Moser, Patrizia L., Streif, Werner, Kolbitsch, Christian, Lorenz, Ingo H.

“…The pig is a suitable animal model for researching blood coagulation and fibrinolysis. The present study therefore aimed to investigate in porcine blood the…”
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Intraventricular pressure in non-communicating hydrocephalus patients before endoscopic third ventriculostomy by Tiefenthaler, Werner, Burtscher, Johannes, Moser, Patrizia L., Lorenz, Ingo H., Kolbitsch, Christian

“…In patients with non-communicating hydrocephalus impairment of cerebral compliance can occur pre- but also intraoperatively. In such patients (n = 6)…”
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How bispectral index compares to spectral entropy of the EEG and A-line ARX index in the same patient by Tiefenthaler, Werner, Colvin, Joshua, Steger, Bernhard, Pfeiffer, Karl P., Moser, Patrizia L., Walde, Janette, Lorenz, Ingo H., Kolbitsch, Christian

“…Bispectral index (BIS) monitoring of depth of anesthesia has pioneered the field for more recent monitoring devices like the A-line ARX Index (AAI) or the…”
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Erythropoietin Contrastingly Affects Bacterial Infection and Experimental Colitis by Inhibiting Nuclear Factor-κB-Inducible Immune Pathways by Nairz, Manfred, Schroll, Andrea, Moschen, Alexander R., Sonnweber, Thomas, Theurl, Milan, Theurl, Igor, Taub, Nicole, Jamnig, Christina, Neurauter, Daniela, Huber, Lukas A., Tilg, Herbert, Moser, Patrizia L., Weiss, Günter

“…Erythropoietin (EPO) is the principal cytokine regulating erythropoiesis through its receptor, EPOR. Interestingly, EPORs are also found on immune cells with…”
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Effects of weight loss induced by bariatric surgery on hepatic adipocytokine expression by Moschen, Alexander R, Molnar, Clemens, Wolf, Anna Maria, Weiss, Helmut, Graziadei, Ivo, Kaser, Susanne, Ebenbichler, Christoph F, Stadlmann, Sylvia, Moser, Patrizia L, Tilg, Herbert

“…Background/Aims Adipocytokines play a key role in the pathophysiology of non-alcoholic fatty liver diseases (NAFLD). Whereas adiponectin has mainly…”
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The Anti-Interleukin-6 Antibody Siltuximab Down-Regulates Genes Implicated inTumorigenesis in Prostate Cancer Patients From a Phase I Study by KARKERA, Jayaprakash, STEINER, Hannes, PANTEL, Klaus, MING QI, CULIG, Zoran, WEIMIN LI, SKRADSKI, Viktor, MOSER, Patrizia L, RIETHDORF, Sabine, REDDY, Manjula, PUCHALSKI, Thomas, SAFER, Karim, PRABHAKAR, Uma

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Nifedipine Affects the Course of Salmonella enterica Serovar Typhimurium Infection by Modulating Macrophage Iron Homeostasis by Mair, Sabine M., Nairz, Manfred, Bellmann-Weiler, Rosa, Muehlbacher, Thomas, Schroll, Andrea, Theurl, Igor, Moser, Patrizia L., Talasz, Heribert, Fang, Ferric C., Weiss, Guenter

“…Background. Iron overload can adversely influence the course of infection by increasing microbial replication and suppressing antimicrobial immune effector…”
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PTEN expression in renal cell carcinoma and oncocytoma and prognosis by Hager, Martina, Haufe, Heike, Kemmerling, Ralf, Mikuz, Gregor, Kolbitsch, Christian, Moser, Patrizia L.

“…Deletion or inactivation of the tumour suppressor gene PTEN (phosphatase and tensin homologue deleted from chromosome 10) contributes to tumorigenesis in a…”
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