Search Results - "MORTENSEN, N J McC"

Cancer surveillance in ulcerative colitis by Chambers, W. M., Warren, B. F., Jewell, D. P., McC. Mortensen, N. J.

“…Background: Patients with ulcerative colitis are at a higher risk of developing colorectal cancer than those without the disease. Surveillance programmes are…”
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Preoperative Chemoradiotherapy and Total Mesorectal Excision Surgery for Locally Advanced Rectal Cancer: Correlation With Rectal Cancer Regression Grade by Wheeler, J M. D, Dodds, E, Warren, B F, Cunningham, C, George, B D, Jones, A C, Mortensen, N J. McC

“…PURPOSE: METHODS: RESULTS:Sixty-five patients with a mean age 65 (range, 32-83) years underwent chemoradiotherapy before surgical resection. Thirty patients…”
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Should ileal pouch-anal anastomosis include mucosectomy? by Chambers, W. M., McC. Mortensen, N. J.

“…Objective  Debate exists as to the benefits of performing mucosectomy as part of pouch surgery for ulcerative colitis (UC) and familial adenomatous polyposis…”
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Long-term follow-up of strictureplasty for Crohn's disease by Fearnhead, N. S., Chowdhury, R., Box, B., George, B. D., Jewell, D. P., Mortensen, N. J. McC

“…Background: Strictureplasty is an effective means of alleviating obstructive Crohn's disease while conserving bowel length. The aim of this study was to…”
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Management of early rectal cancer by Tytherleigh, M. G., Warren, B. F., McC. Mortensen, N. J.

“…Background: Early rectal cancer (ERC) is adenocarcinoma that has invaded into, but not extended beyond, the submucosa of the rectum (that is a T1 tumour)…”
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The management and outcome of anastomotic leaks in colorectal surgery by Khan, A. A., Wheeler, J. M. D., Cunningham, C., George, B., Kettlewell, M., Mortensen, N. J. McC

“…Purpose  Anastomotic leaks in colorectal surgery are associated with significant morbidity and mortality and may result in poor functional and oncological…”
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Oral nifedipine reduces resting anal pressure and heals chronic anal fissure by Cook, T. A., Humphreys, M. M. Smilgin, Mortensen, N. J. McC

“…Background: Topical preparations have been used in the treatment of anal fissure. However, they are not universally successful and there is confusion over the…”
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Histopathological mimicry in mucosal prolapse by Singh, B, Mortensen, N J McC, Warren, B F

“…Mucosal prolapse solitary rectal ulcer syndrome is a condition which has frequently confused both pathologists and surgeons alike. Despite its recognition in…”
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L-Erythro-methoxamine is more potent than phenylephrine in effecting contraction of internal anal sphincter in vitro by Jones, O. M., Thompson, J. M., Brading, A. F., Mortensen, N. J. McC

“…Background: Topical phenylephrine has been shown to increase resting anal canal pressure in normal and incontinent individuals. However, high concentrations of…”
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A predictive model for local recurrence after transanal endoscopic microsurgery for rectal cancer by Bach, S. P., Hill, J., Monson, J. R. T., Simson, J. N. L., Lane, L., Merrie, A., Warren, B., Mortensen, N. J. McC

“…Background: The outcome of local excision of early rectal cancer using transanal endoscopic microsurgery (TEM) lacks consensus. Screening has substantially…”
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Long-Term Function After Restorative Proctocolectomy by Wheeler, J M. D, Banerjee, A, Ahuja, N, Jewell, D P, Mortensen, N J. McC

“…PURPOSE: METHODS: RESULTS: CONCLUSIONS:…”
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Randomized Clinical Trial of Botulinum Toxin Plus Glyceryl Trinitrate vs. Botulinum Toxin Alone for Medically Resistant Chronic Anal Fissure: Overall Poor Healing Rates by Jones, O M, Ramalingam, T, Merrie, A, Cunningham, C, George, B D, Mortensen, N J. McC, Lindsey, I

“…PURPOSE: METHODS: RESULTS:Thirty patients were randomized. Two-thirds of patients had maximum anal resting pressures below or within the normal range at entry…”
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European evidence-based Consensus on the management of ulcerative colitis: Current management by Travis, S P L, Stange, E F, Lémann, M, Oresland, T, Bemelman, W A, Chowers, Y, Colombel, J F, D'Haens, G, Ghosh, S, Marteau, P, Kruis, W, Mortensen, N J McC, Penninckx, F, Gassull, M

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Immune therapy in inflammatory bowel disease and models of colitis by Singh, B., Powrie, F., Mortensen, N. J. McC

“…Background: A proliferation of animal models has not only improved our understanding of inflammatory bowel disease, it has also formed the basis of new…”
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Chronic anal fissure by Lindsey, I., Jones, O. M., Cunningham, C., Mortensen, N. J. McC

“…Background: The treatment of chronic anal fissure has shifted in recent years from surgical to medical. Methods: A Medline search of studies relevant to modern…”
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Perianal Crohn's disease by Singh, B., McC. Mortensen, N. J., Jewell, D. P., George, B.

“…Background: The management of perianal Crohn's disease is difficult. A wide variety of treatment options exist although few are evidence based. Methods: A…”
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Quantification of histologic regression of rectal cancer after irradiation: a proposal for a modified staging system by Wheeler, J M D, Warren, B F, Mortensen, N J McC, Ekanyaka, N, Kulacoglu, H, Jones, A C, George, B D, Kettlewell, M G W

“…Long-course preoperative radiotherapy has been recommended for rectal carcinoma when there is concern about the ability to perform a curative resection, for…”
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Anatomy of Denonvilliers' fascia and pelvic nerves, impotence, and implications for the colorectal surgeon by Lindsey, I., Guy, R. J., Warren, B. F., Mortensen, N. J. McC

“…Background The development and anatomy of Denonvilliers' fascia have been controversial for many years and confusion exists about its operative appearance…”
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DNA mismatch repair genes and colorectal cancer by WHEELER, J M D, BODMER, W F, MORTENSEN, N J McC

“…Mutations in hMSH2 and hMLH1 account for the majority of reported HNPCC cases, 15 although two additional homologues of the mutL gene (hPMS1 on chromosome 2q…”
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Options for sphincter preservation in surgery for low rectal cancer by Tytherleigh, M. G., Mortensen, N. J. McC

“…Background: Abdominoperineal excision of the rectum with a permanent end‐sigmoid colostomy was the classical operation for cancer of the distal third of the…”
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