Search Results - "MORTARA, A"
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The diverse and dynamic nature of Leishmania parasitophorous vacuoles studied by multidimensional imaging
Published in PLoS neglected tropical diseases (01-02-2012)“…An important area in the cell biology of intracellular parasitism is the customization of parasitophorous vacuoles (PVs) by prokaryotic or eukaryotic…”
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Trypanosoma cruzi subverts the sphingomyelinase-mediated plasma membrane repair pathway for cell invasion
Published in The Journal of experimental medicine (09-05-2011)“…Upon host cell contact, the protozoan parasite Trypanosoma cruzi triggers cytosolic Ca(2+) transients that induce exocytosis of lysosomes, a process required…”
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Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi
Published in Frontiers in microbiology (28-02-2018)“…This study evaluated the participation of host cell Rho-family GTPases and their effector proteins in the actin-dependent invasion by extracellular amastigotes…”
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Impact of diabetes on COVID-19-related in-hospital mortality: a retrospective study from Northern Italy
Published in Journal of endocrinological investigation (01-04-2021)“…Purpose The purpose of this study was to evaluate the impact of pre-existing diabetes on in-hospital mortality in patients admitted for Coronavirus Disease…”
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DNA damage and oxidative stress in human cells infected by Trypanosoma cruzi
Published in PLoS pathogens (01-04-2021)“…Trypanosoma cruzi is the etiologic agent of Chagas' disease. Infected cells with T. cruzi activate several responses that promote unbalance of reactive oxygen…”
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Amastigote Synapse: The Tricks of Trypanosoma cruzi Extracellular Amastigotes
Published in Frontiers in microbiology (27-06-2018)“…To complete its life cycle within the mammalian host, , the agent of Chagas' disease, must enter cells. Trypomastigotes originating from the insect vector…”
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ERM Proteins Play Distinct Roles in Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi
Published in Frontiers in microbiology (21-11-2017)“…The protozoan parasite is the causative agent of Chagas' disease. In mammalian hosts, alternates between trypomastigote and amastigote forms. Additionally,…”
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Parasite-Mediated Remodeling of the Host Microfilament Cytoskeleton Enables Rapid Egress of Trypanosoma cruzi following Membrane Rupture
Published in mBio (29-06-2021)“…Chagas' disease arises as a direct consequence of the lytic cycle of Trypanosoma cruzi in the mammalian host. While invasion is well studied for this pathogen,…”
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Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species
Published in PLoS neglected tropical diseases (27-02-2017)“…Interleukin-32 (IL-32) is expressed in lesions of patients with American Tegumentary Leishmaniasis (ATL), but its precise role in the disease remains unknown…”
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BALB/c and C57BL/6 Mice Cytokine Responses to Trypanosoma cruzi Infection Are Independent of Parasite Strain Infectivity
Published in Frontiers in microbiology (26-03-2018)“…is the etiologic agent of Chagas' disease, which affects 6-7 million people worldwide. Different strains of present specific genotypic and phenotypic…”
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Candida albicans : The Ability to Invade Epithelial Cells and Survive under Oxidative Stress Is Unlinked to Hyphal Length
Published in Frontiers in microbiology (17-07-2017)“…In its hyphal form, invades epithelial and endothelial cells by two distinct mechanisms: active penetration and induced endocytosis. The latter is dependent on…”
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Trypanosoma cruzi: role of δ-amastin on extracellular amastigote cell invasion and differentiation
Published in PloS one (18-12-2012)“…Trypanosoma cruzi is a protozoan parasite that comprises different phylogenetic groups and is the causative agent of Chagas' disease. Different T. cruzi…”
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CD4+CD25+ T Cells in Skin Lesions of Patients with Cutaneous Leishmaniasis Exhibit Phenotypic and Functional Characteristics of Natural Regulatory T Cells
Published in The Journal of infectious diseases (01-05-2006)“…Endogenous regulatory T (Treg) cells are involved in the control of infections, including Leishmania infection in mice. Leishmania viannia braziliensis is the…”
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Fusion between Leishmania amazonensis and Leishmania major parasitophorous vacuoles: live imaging of coinfected macrophages
Published in PLoS neglected tropical diseases (07-12-2010)“…Protozoan parasites of the genus Leishmania alternate between flagellated, elongated extracellular promastigotes found in insect vectors, and round-shaped…”
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A Carbohydrate Moiety of Secreted Stage-Specific Glycoprotein 4 Participates in Host Cell Invasion by Trypanosoma cruzi Extracellular Amastigotes
Published in Frontiers in microbiology (10-04-2018)“…is the etiologic agent of Chagas' disease. It is known that amastigotes derived from trypomastigotes in the extracellular milieu are infective and …”
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Peptide R18H from BRN2 Transcription Factor POU Domain Displays Antitumor Activity In Vitro and In Vivo and Induces Apoptosis in B16F10-Nex2 Cells
Published in Anti-cancer agents in medicinal chemistry (01-01-2019)“…BRN2 transcription factor is associated with the development of malignant melanoma. The cytotoxic activities and cell death mechanism against B16F10-Nex2 cells…”
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Leishmania (Viannia) braziliensis Inositol Phosphorylceramide: Distinctive Sphingoid Base Composition
Published in Frontiers in microbiology (04-08-2017)“…Inositol phosphorylceramide (IPC), the major sphingolipid in the genus but not found in mammals, is considered a potentially useful target for chemotherapy…”
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Effective Topical Treatment of Subcutaneous Murine B16F10-Nex2 Melanoma By the Antimicrobial Peptide Gomesin
Published in Neoplasia (New York, N.Y.) (01-01-2008)“…Gomesin is a potent antimicrobial peptide (AMP) isolated from hemocytes of the spider Acanthoscurria gomesiana. The present study aimed at determining whether…”
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The repetitive cytoskeletal protein H49 of Trypanosoma cruzi is a calpain-like protein located at the flagellum attachment zone
Published in PloS one (11-11-2011)“…Trypanosoma cruzi has a single flagellum attached to the cell body by a network of specialized cytoskeletal and membranous connections called the flagellum…”
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