Search Results - "MORSE, H. C"

Specific deletion of TRAF3 in B lymphocytes leads to B-lymphoma development in mice by Moore, C R, Liu, Y, Shao, C, Covey, L R, Morse, H C, Xie, P

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The tumor microenvironment is the main source of IL-6 for plasma cell tumor development in mice by Rosean, T R, Tompkins, V S, Olivier, A K, Sompallae, R, Norian, L A, Morse, H C, Waldschmidt, T J, Janz, S

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Loss of a chromosomal region with synteny to human 13q14 occurs in mouse chronic lymphocytic leukemia that originates from early-generated B-1 B cells by Hayakawa, K, Formica, A M, Colombo, M J, Shinton, S A, Brill-Dashoff, J, Morse III, H C, Li, Y-S, Hardy, R R

“…A common feature of B-cell chronic lymphocytic leukemia (CLL) is chromosomal loss of 13q14, containing the miR15a/16-1 locus controlling B-cell proliferation…”
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Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas by DAWSON, D. W, HONG, J. S, MORSE, H. C, SAID, J, PLASS, C, TEITELLL, M. A, SHEN, R. R, FRENCH, S. W, TROKE, J. J, WU, Y.-Z, CHEN, S.-S, GUI, D, REGELSON, M, MARAHRENS, Y

“…Most human lymphomas originate from transformed germinal center (GC) B lymphocytes. While activating mutations and translocations of MYC, BCL2 and BCL6 promote…”
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Ectopic expression of wild-type FGFR3 cooperates with MYC to accelerate development of B-cell lineage neoplasms by Zingone, A, Cultraro, C M, Shin, D-M, Bean, C M, Morse, H C, Janz, S, Kuehl, W M

“…The t(4;14) translocation in multiple myeloma (MM) simultaneously dysregulates two apparent oncogenes: fibroblast growth factor receptor 3 ( FGFR3 ) controlled…”
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The nonhomologous end joining factor Artemis suppresses multi-tissue tumor formation and prevents loss of heterozygosity by WOO, Y, WRIGHT, S. M, BRONSON, R. T, MORSE, H. C, ROOPENIAN, D, MILLS, K. D, MAAS, S. A, ALLEY, T. L, CADDLE, L. B, KAMDAR, S, AFFOURTIT, J, FOREMAN, O, AKESON, E. C, SHAFFER, D

“…Nonhomologous end joining (NHEJ) is a critical DNA repair pathway, with proposed tumor suppression functions in many tissues. Mutations in the NHEJ factor…”
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The Histopathologic and Molecular Basis for the Diagnosis of Histiocytic Sarcoma and Histiocyte–Associated Lymphoma of Mice by Hao, X., Fredrickson, T. N., Chattopadhyay, S. K., Han, W., Qi, C.–F., Wang, Z., Ward, J. M., Hartley, J. W., Morse, H. C.

“…Histiocytic sarcoma (HS) and histiocyte–associated lymphoma (HAL) of mice are difficult to distinguish histologically. Studies of multiple cases initially…”
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Enhanced pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of interleukin-4 (IL-4) and IL-10 by CONNORS, M, GIESE, N. A, KULKARNI, A. B, FIRESTONE, C.-Y, MORSE, H. C, MURPHY, B. R

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Burkitt lymphoma in the mouse by Kovalchuk, A L, Qi, C F, Torrey, T A, Taddesse-Heath, L, Feigenbaum, L, Park, S S, Gerbitz, A, Klobeck, G, Hoertnagel, K, Polack, A, Bornkamm, G W, Janz, S, Morse, 3rd, H C

“…Chromosomal translocations juxtaposing the MYC protooncogene with regulatory sequences of immunoglobulin (Ig) H chain or kappa (Ig kappa) or lambda (Ig lambda)…”
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Prdm14 initiates lymphoblastic leukemia after expanding a population of cells resembling common lymphoid progenitors by Dettman, E J, Simko, S J, Ayanga, B, Carofino, B L, Margolin, J F, Morse, H C, Justice, M J

“…Understanding the heterogeneous genetic mechanisms of tumor initiation in lymphoid leukemias (LL) will lead to improvements in prognostic classification and…”
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18F-FDG-PET/CT imaging in an IL-6- and MYC-driven mouse model of human multiple myeloma affords objective evaluation of plasma cell tumor progression and therapeutic response to the proteasome inhibitor ixazomib by Duncan, K, Rosean, T R, Tompkins, V S, Olivier, A, Sompallae, R, Zhan, F, Tricot, G, Acevedo, M R, Ponto, L L B, Walsh, S A, Tygrett, L T, Berger, A J, Waldschmidt, T, Morse, H C, Sunderland, J J, Janz, S

“…18 F-fluorodeoxyglucose positron emission tomography (FDG-PET) and computed tomography (CT) are useful imaging modalities for evaluating tumor progression and…”
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Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type‐1 and type‐2 cytokine‐mediated inflammatory reactions by Hoffmann, Karl F., McCarty, Thomas C., Segal, David H., Chiaramonte, Monica, Hesse, Matthias, Davis, Eric M., Cheever, Allen W., Meltzer, Paul S., III, Herbert C. Morse, Wynn, Thomas A.

“…ABSTRACT Development of polarized immune responses controls resistance and susceptibility to many microorganisms. However, studies of several infectious,…”
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DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus by Jhappan, Chamelli, Morse, Herbert C, Fleischmann, Robert D, Gottesman, Michael M, Merlino, Glenn

“…Severe combined immunodeficiency (SCID) mice are defective in their ability to rearrange their variable (V), diversity (D) and joining (J) genetic elements to…”
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Analysis of granuloma formation in double cytokine-deficient mice reveals a central role for IL-10 in polarizing both T helper cell 1- and T helper cell 2-type cytokine responses in vivo by Wynn, TA, Morawetz, R, Scharton-Kersten, T, Hieny, S, Morse, HC, 3rd, Kuhn, R, Muller, W, Cheever, AW, Sher, A

“…In response to i.v.-injected eggs of Schistosoma mansoni, normal mice develop a dominant type 2 response, whereas IL-10-deficient animals generate a mixed type…”
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Retrovirus-induced immunodeficiency in the mouse: MAIDS as a model for AIDS by Morse, 3rd, H C, Chattopadhyay, S K, Makino, M, Fredrickson, T N, Hügin, A W, Hartley, J W

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Efficiency Alleles of the Pctr1 Modifier Locus for Plasmacytoma Susceptibility by Zhang, Shuling-L., DuBois, Wendy, Ramsay, Edward S., Bliskovski, Valeri, Morse, Herbert C., Taddesse-Heath, Leki, Vass, William C., DePinho, Ronald A., Mock, Beverly A.

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Interferon (IFN) consensus sequence-binding protein, a transcription factor of the IFN regulatory factor family, regulates immune responses in vivo through control of interleukin 12 expression by Giese, N A, Gabriele, L, Doherty, T M, Klinman, D M, Tadesse-Heath, L, Contursi, C, Epstein, S L, Morse, 3rd, H C

“…Mice with a null mutation of the gene encoding interferon consensus sequence-binding protein (ICSBP) develop a chronic myelogenous leukemia-like syndrome and…”
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Regulation of apoptosis in myeloid cells by interferon consensus sequence-binding protein by Gabriele, L, Phung, J, Fukumoto, J, Segal, D, Wang, I M, Giannakakou, P, Giese, N A, Ozato, K, Morse, 3rd, H C

“…Mice with a null mutation of the gene encoding interferon consensus sequence-binding protein (ICSBP) develop a disease with marked expansion of granulocytes…”
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Cellular Motor Protein KIF-4 Associates with Retroviral Gag by Tang, Y, Winkler, U, Freed, E O, Torrey, T A, Kim, W, Li, H, Goff, S P, Morse, 3rd, H C

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v-cbl, an Oncogene from a Dual-Recombinant Murine Retrovirus that Induces Early B-Lineage Lymphomas by Langdon, Wallace Y., Hartley, Janet W., Klinken, S. Peter, Ruscetti, Sandra K., Morse, Herbert C.

“…Cas NS-1 is an acutely transforming murine retrovirus that induces pre-B and pro-B cell lymphomas. Molecular cloning showed it was generated from the ecotropic…”
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