Search Results - "MORROW, JASON D."

Quantification of Isoprostanes as Indices of Oxidant Stress and the Risk of Atherosclerosis in Humans by Morrow, Jason D

“…Enhanced oxidant stress occurring either locally in the vessel wall or systemically is implicated in the pathogenesis of atherosclerosis in humans…”
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A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice by Barger, Jamie L, Kayo, Tsuyoshi, Vann, James M, Arias, Edward B, Wang, Jelai, Hacker, Timothy A, Wang, Ying, Raederstorff, Daniel, Morrow, Jason D, Leeuwenburgh, Christiaan, Allison, David B, Saupe, Kurt W, Cartee, Gregory D, Weindruch, Richard, Prolla, Tomas A

“…Resveratrol in high doses has been shown to extend lifespan in some studies in invertebrates and to prevent early mortality in mice fed a high-fat diet. We fed…”
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Measurement of F2-isoprostanes as an index of oxidative stress in vivo by Roberts, L.Jackson, Morrow, Jason D

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Quantification of F2-isoprostanes as a biomarker of oxidative stress by Milne, Ginger L, Sanchez, Stephanie C, Musiek, Erik S, Morrow, Jason D

“…Oxidant stress has been implicated in a wide variety of disease processes. One method to quantify oxidative injury is to measure lipid peroxidation…”
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Quantification of F2-isoprostanes as a reliable index of oxidative stress in vivo using gas chromatography-mass spectrometry (GC-MS) method by Liu, Wei, Morrow, Jason D, Yin, Huiyong

“…Free radical-induced lipid peroxidation has been implicated in a number of human diseases including atherosclerosis, cancer, and neurodegenerative diseases…”
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Accelerated Telomere Shortening in Response to Life Stress by Epel, Elissa S., Blackburn, Elizabeth H., Lin, Jue, Dhabhar, Firdaus S., Adler, Nancy E., Morrow, Jason D., Cawthon, Richard M.

“…Numerous studies demonstrate links between chronic stress and indices of poor health, including risk factors for cardiovascular disease and poorer immune…”
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Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription by Yang, Lichuan, Calingasan, Noel Y, Thomas, Bobby, Chaturvedi, Rajnish K, Kiaei, Mahmoud, Wille, Elizabeth J, Liby, Karen T, Williams, Charlotte, Royce, Darlene, Risingsong, Renee, Musiek, Eric S, Morrow, Jason D, Sporn, Michael, Beal, M Flint

“…The NF-E2-related factor-2 (Nrf2)/antioxidant response element (ARE) signaling pathway regulates phase 2 detoxification genes, including a variety of…”
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Cyclooxygenase-2-derived Prostaglandin E2 Directs Oocyte Maturation by Differentially Influencing Multiple Signaling Pathways by Takahashi, Toshifumi, Morrow, Jason D., Wang, Haibin, Dey, Sudhansu K.

“…The process of oocyte maturation, which impacts ovulation and fertilization, is complex and requires an integration of the endocrine, paracrine, juxtacrine,…”
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Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment by Markesbery, William R., Kryscio, Richard J., Lovell, Mark A., Morrow, Jason D.

“…Multiple studies demonstrate that the brain in Alzheimer's disease (AD) contains extensive oxidative damage. Most of these studies used advanced‐stage AD…”
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Novel n-3 Fatty Acid Oxidation Products Activate Nrf2 by Destabilizing the Association between Keap1 and Cullin3 by Gao, Ling, Wang, Jiakun, Sekhar, Konjeti R., Yin, Huiyong, Yared, Nicholas F., Schneider, Scott N., Sasi, Soumya, Dalton, Timothy P., Anderson, Mark E., Chan, Jefferson Y., Morrow, Jason D., Freeman, Michael L.

“…Consumption of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can mitigate the progression of diseases in which oxidative stress represents a…”
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Acetylcholine‐induced endothelium‐dependent contractions in the SHR aorta: the Janus face of prostacyclin by Gluais, Pascale, Lonchampt, Michel, Morrow, Jason D, Vanhoutte, Paul M, Feletou, Michel

“…In the spontaneously hypertensive rat (SHR) and aging Wistar–Kyoto rats (WKY), acetylcholine releases an endothelium‐derived contracting factor (EDCF) produced…”
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Formation of F-ring Isoprostane-like Compounds (F3-Isoprostanes) in Vivo from Eicosapentaenoic Acid by Gao, Ling, Yin, Huiyong, Milne, Ginger L., Porter, Ned A., Morrow, Jason D.

“…Eicosapentaenoic acid (EPA, C20:5, ω-3) is the most abundant polyunsaturated fatty acid (PUFA) in fish oil. Recent studies suggest that the beneficial effects…”
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The effect of vitamins C and E on biomarkers of oxidative stress depends on baseline level by Block, Gladys, Jensen, Christopher D., Morrow, Jason D., Holland, Nina, Norkus, Edward P., Milne, Ginger L., Hudes, Mark, Dalvi, Tapashi B., Crawford, Patricia B., Fung, Ellen B., Schumacher, Laurie, Harmatz, Paul

“…Oxidative stress is elevated in obesity, and may be a major mechanism for obesity-related diseases. Nonsmokers ( n = 396) were randomized to 1000 mg/day…”
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Angiotensin II Induces Interleukin-6 in Humans Through a Mineralocorticoid Receptor–Dependent Mechanism by Luther, James M, Gainer, James V, Murphey, Laine J, Yu, Chang, Vaughan, Douglas E, Morrow, Jason D, Brown, Nancy J

“…This study tested the hypothesis that angiotensin promotes oxidative stress and inflammation in humans via aldosterone and the mineralocorticoid receptor. We…”
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Fatty Acid Oxidation in the Pathogenesis of Alzheimer's Disease by Montine, Thomas J., Morrow, Jason D.

“…Alzheimer's disease (AD) is the most common dementing illness of the elderly and is a mounting public health problem. Pharmacoepidemiological data, analytical…”
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Dietary fish oil exerts hypolipidemic effects in lean and insulin sensitizing effects in obese LDLR-/- mice by Saraswathi, Viswanathan, Morrow, Jason D, Hasty, Alyssa H

“…Obesity is often associated with dyslipidemia, insulin resistance, and hypertension. Together, these metabolic perturbations greatly increase the risk of…”
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A Phase II Study of Celecoxib in Combination with Paclitaxel, Carboplatin, and Radiotherapy for Patients with Inoperable Stage IIIA/B Non–Small Cell Lung Cancer by MUTTER, Robert, BO LU, CHOY, Hak, CARBONE, David P, CSIKI, Lldiko, MORETTI, Luigi, JOHNSON, David H, MORROVV, Jason D, SANDLER, Alan B, SHYR, Yu, FEI YE

“…Purpose: Cyclooxygenase (COX)-2 up-regulation plays an important role in the pathogenesis of lung cancer. Selective COX-2 inhibitors have promoted…”
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Metabolism of the Endocannabinoids, 2-Arachidonylglycerol and Anandamide, into Prostaglandin, Thromboxane, and Prostacyclin Glycerol Esters and Ethanolamides by Kozak, Kevin R, Crews, Brenda C, Morrow, Jason D, Wang, Lee-Ho, Ma, Y Henry, Weinander, Rolf, Jakobsson, Per-Johan, Marnett, Lawrence J

“…Cyclooxygenase-2 (COX-2) action on the endocannabinoids, 2-arachidonylglycerol (2-AG) and anandamide (AEA), generates prostaglandin glycerol esters (PG-G) and…”
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Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II by Qi, Zhonghua, Hao, Chuan-Ming, Langenbach, Robert I, Breyer, Richard M, Redha, Reyadh, Morrow, Jason D, Breyer, Matthew D

“…Therapeutic use of cyclooxygenase-inhibiting (COX-inhibiting) nonsteroidal antiinflammatory drugs (NSAIDs) is often complicated by renal side effects including…”
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Formation of Highly Reactive Cyclopentenone Isoprostane Compounds (A3/J3-Isoprostanes) in Vivo from Eicosapentaenoic Acid by Brooks, Joshua D., Milne, Ginger L., Yin, Huiyong, Sanchez, Stephanie C., Porter, Ned A., Morrow, Jason D.

“…Omega-3 (ω-3) polyunsaturated fatty acids (PUFAs) found in marine fish oils are known to suppress inflammation associated with a wide variety of diseases…”
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