Search Results - "MORITZ, Robert L"
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The ProteomeXchange consortium in 2017: supporting the cultural change in proteomics public data deposition
Published in Nucleic acids research (04-01-2017)“…The ProteomeXchange (PX) Consortium of proteomics resources (http://www.proteomexchange.org) was formally started in 2011 to standardize data submission and…”
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Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry
Published in Nature communications (21-08-2017)“…Quantitative proteomics employing mass spectrometry is an indispensable tool in life science research. Targeted proteomics has emerged as a powerful approach…”
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Trans-Proteomic Pipeline, a standardized data processing pipeline for large-scale reproducible proteomics informatics
Published in Proteomics. Clinical applications (01-08-2015)“…Democratization of genomics technologies has enabled the rapid determination of genotypes. More recently the democratization of comprehensive proteomics…”
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iProphet: Multi-level Integrative Analysis of Shotgun Proteomic Data Improves Peptide and Protein Identification Rates and Error Estimates
Published in Molecular & cellular proteomics (01-12-2011)“…The combination of tandem mass spectrometry and sequence database searching is the method of choice for the identification of peptides and the mapping of…”
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Human SRMAtlas: A Resource of Targeted Assays to Quantify the Complete Human Proteome
Published in Cell (28-07-2016)“…The ability to reliably and reproducibly measure any protein of the human proteome in any tissue or cell type would be transformative for understanding…”
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The Human Plasma Proteome Draft of 2017: Building on the Human Plasma PeptideAtlas from Mass Spectrometry and Complementary Assays
Published in Journal of proteome research (01-12-2017)“…Human blood plasma provides a highly accessible window to the proteome of any individual in health and disease. Since its inception in 2002, the Human Proteome…”
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Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics
Published in PLoS pathogens (01-04-2016)“…Malaria parasite infection is initiated by the mosquito-transmitted sporozoite stage, a highly motile invasive cell that targets hepatocytes in the liver for…”
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Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 3.0
Published in Journal of proteome research (06-12-2019)“…The Human Proteome Organization’s (HUPO) Human Proteome Project (HPP) developed Mass Spectrometry (MS) Data Interpretation Guidelines that have been applied…”
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Building ProteomeTools based on a complete synthetic human proteome
Published in Nature methods (01-03-2017)“…The ProteomeTools project provides the proteomics community with a physical synthetic tryptic peptide resource and a digital LC-MS/MS data resource covering…”
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Kojak: Efficient Analysis of Chemically Cross-Linked Protein Complexes
Published in Journal of proteome research (01-05-2015)“…Protein chemical cross-linking and mass spectrometry enable the analysis of protein–protein interactions and protein topologies; however, complicated…”
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Proteomics Analysis of A33 Immunoaffinity-purified Exosomes Released from the Human Colon Tumor Cell Line LIM1215 Reveals a Tissue-specific Protein Signature
Published in Molecular & cellular proteomics (01-02-2010)“…Exosomes are 40–100-nm-diameter nanovesicles of endocytic origin that are released from diverse cell types. To better understand the biological role of…”
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PTMProphet: Fast and Accurate Mass Modification Localization for the Trans-Proteomic Pipeline
Published in Journal of proteome research (06-12-2019)“…Spectral matching sequence database search engines commonly used on mass spectrometry-based proteomics experiments excel at identifying peptide sequence ions,…”
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The Mtb Proteome Library: A Resource of Assays to Quantify the Complete Proteome of Mycobacterium tuberculosis
Published in Cell host & microbe (15-05-2013)“…Research advancing our understanding of Mycobacterium tuberculosis (Mtb) biology and complex host-Mtb interactions requires consistent and precise quantitative…”
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Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites
Published in Nature communications (31-10-2019)“…Plasmodium sporozoites are transmitted from infected mosquitoes to mammals, and must navigate the host skin and vasculature to infect the liver. This journey…”
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A complete mass-spectrometric map of the yeast proteome applied to quantitative trait analysis
Published in Nature (London) (14-02-2013)“…High-throughput peptide synthesis and mass spectrometry are used to generate a near-complete reference map of the Saccharomyces cerevisiae proteome; two…”
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Total and Putative Surface Proteomics of Malaria Parasite Salivary Gland Sporozoites
Published in Molecular & cellular proteomics (01-05-2013)“…Malaria infections of mammals are initiated by the transmission of Plasmodium salivary gland sporozoites during an Anopheles mosquito vector bite. Sporozoites…”
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DIALib-QC an assessment tool for spectral libraries in data-independent acquisition proteomics
Published in Nature communications (16-10-2020)“…Data-independent acquisition (DIA) mass spectrometry, also known as Sequential Window Acquisition of all Theoretical Mass Spectra (SWATH), is a popular…”
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Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 2.1
Published in Journal of proteome research (04-11-2016)“…Every data-rich community research effort requires a clear plan for ensuring the quality of the data interpretation and comparability of analyses. To address…”
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Lumenal calcification and microvasculopathy in fetuin-A-deficient mice lead to multiple organ morbidity
Published in PloS one (19-02-2020)“…The plasma protein fetuin-A mediates the formation of protein-mineral colloids known as calciprotein particles (CPP)-rapid clearance of these CPP by the…”
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Reproducible quantification of cancer-associated proteins in body fluids using targeted proteomics
Published in Science translational medicine (11-07-2012)“…The rigorous testing of hypotheses on suitable sample cohorts is a major limitation in translational research. This is particularly the case for the validation…”
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