Search Results - "MORIS, Philippe"

Different Adjuvants Induce Common Innate Pathways That Are Associated with Enhanced Adaptive Responses against a Model Antigen in Humans by Burny, Wivine, Callegaro, Andrea, Bechtold, Viviane, Clement, Frédéric, Delhaye, Sophie, Fissette, Laurence, Janssens, Michel, Leroux-Roels, Geert, Marchant, Arnaud, van den Berg, Robert A, Garçon, Nathalie, van der Most, Robbert, Didierlaurent, Arnaud M

“…To elucidate the role of innate responses in vaccine immunogenicity, we compared early responses to hepatitis B virus (HBV) surface antigen (HBsAg) combined…”
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Randomized, Double-Blind, Reference-Controlled, Phase 2a Study Evaluating the Immunogenicity and Safety of OVX836, A Nucleoprotein-Based Influenza Vaccine by Leroux-Roels, Isabel, Waerlop, Gwenn, Tourneur, Jessika, De Boever, Fien, Maes, Catherine, Bruhwyler, Jacques, Guyon-Gellin, Delphine, Moris, Philippe, Del Campo, Judith, Willems, Paul, Leroux-Roels, Geert, Le Vert, Alexandre, Nicolas, Florence

“…OVX836 is a recombinant protein-based vaccine targeting the highly conserved influenza nucleoprotein (NP), which aims to confer a broad-spectrum protection…”
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Ad35.CS.01-RTS,S/AS01 Heterologous Prime Boost Vaccine Efficacy against Sporozoite Challenge in Healthy Malaria-Naïve Adults by Ockenhouse, Christian F, Regules, Jason, Tosh, Donna, Cowden, Jessica, Kathcart, April, Cummings, James, Paolino, Kristopher, Moon, James, Komisar, Jack, Kamau, Edwin, Oliver, Thomas, Chhoeu, Austin, Murphy, Jitta, Lyke, Kirsten, Laurens, Matthew, Birkett, Ashley, Lee, Cynthia, Weltzin, Rich, Wille-Reece, Ulrike, Sedegah, Martha, Hendriks, Jenny, Versteege, Isabella, Pau, Maria Grazia, Sadoff, Jerold, Vanloubbeeck, Yannick, Lievens, Marc, Heerwegh, Dirk, Moris, Philippe, Guerra Mendoza, Yolanda, Jongert, Erik, Cohen, Joe, Voss, Gerald, Ballou, W Ripley, Vekemans, Johan

“…In an observer blind, phase 2 trial, 55 adults were randomized to receive one dose of Ad35.CS.01 vaccine followed by two doses of RTS,S/AS01 (ARR-group) or…”
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Characterization of T-cell immune responses in clinical trials of the candidate RTS,S malaria vaccine by Moris, Philippe, Jongert, Erik, van der Most, Robbert G.

“…The candidate malaria vaccine RTS,S has demonstrated 45.7% efficacy over 18 months against all clinical disease in a phase-III field study of African children…”
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T Cell Responses to the RTS,S/AS01E and RTS,S/AS02D Malaria Candidate Vaccines Administered According to Different Schedules to Ghanaian Children by Ansong, Daniel, Asante, Kwaku P., Vekemans, Johan, Owusu, Sandra K., Owusu, Ruth, Brobby, Naana A. W., Dosoo, David, Osei-Akoto, Alex, Osei-Kwakye, Kingsley, Asafo-Adjei, Emmanuel, Boahen, Kwadwo O., Sylverken, Justice, Adjei, George, Sambian, David, Apanga, Stephen, Kayan, Kingsley, Janssens, Michel H., Lievens, Marc J. J., Olivier, Aurelie C., Jongert, Erik, Dubois, Patrice, Savarese, Barbara M., Cohen, Joe, Antwi, Sampson, Greenwood, Brian M., Evans, Jennifer A., Agbenyega, Tsiri, Moris, Philippe J., Owusu-Agyei, Seth

“…Background The Plasmodium falciparum pre-erythrocytic stage candidate vaccine RTS,S is being developed for protection of young children against malaria in…”
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Protective immunity induced with the RTS,S/AS vaccine is associated with IL-2 and TNF-α producing effector and central memory CD4 T cells by Lumsden, Joanne M, Schwenk, Robert J, Rein, Lisa E, Moris, Philippe, Janssens, Michel, Ofori-Anyinam, Opokua, Cohen, Joe, Kester, Kent E, Heppner, D Gray, Krzych, Urszula

“…A phase 2a RTS,S/AS malaria vaccine trial, conducted previously at the Walter Reed Army Institute of Research, conferred sterile immunity against a primary…”
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A statistical interaction between circumsporozoite protein-specific T cell and antibody responses and risk of clinical malaria episodes following vaccination with RTS,S/AS01E by Ndungu, Francis M, Mwacharo, Jedidah, Kimani, Domtila, Kai, Oscar, Moris, Philippe, Jongert, Erik, Vekemans, Johan, Olotu, Ally, Bejon, Philip

“…The candidate malaria vaccine RTS,S/AS01(E) provides significant but partial protection from clinical malaria. On in vitro circumsporozoite protein (CSP)…”
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Characterization of B-cell and T-cell responses to a tetravalent dengue purified inactivated vaccine in healthy adults by Friberg, Heather, Gargulak, Morgan, Kong, Amanda, Lin, Leyi, Martinez, Luis J., Schmidt, Alexander C., Paris, Robert M., Jarman, Richard G., Diaz, Clemente, Thomas, Stephen J., Moris, Philippe, Currier, Jeffrey R.

“…The increasing global impact of dengue underscores the need for a dengue virus (DENV) vaccine. We assessed B-cell and T-cell responses following vaccination…”
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Comparison of the immunogenicity of the human papillomavirus (HPV)-16/18 vaccine and the HPV-6/11/16/18 vaccine for oncogenic non-vaccine types HPV-31 and HPV-45 in healthy women aged 18-45 years by Einstein, Mark H., Baron, Mira, Levin, Myron J, Chatterjee, Archana, Fox, Bradley, Scholar, Sofia, Rosen, Jeffrey, Chakhtoura, Nahida, Lebacq, Marie, van der Most, Robbert, Moris, Philippe, Giannini, Sandra L., Schuind, Anne, Datta, Sanjoy Kumar, Descamps, Dominique

“…Protection against oncogenic non-vaccine types (cross-protection) offered by human papillomavirus (HPV) vaccines may provide a significant medical benefit…”
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Comparative humoral and cellular immunogenicity and safety of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine and HPV-6/11/16/18 vaccine in healthy women aged 18-45 years: Follow-up through Month 48 in a Phase III randomized study by Einstein, Mark H, Levin, Myron J, Chatterjee, Archana, Chakhtoura, Nahida, Takacs, Peter, Catteau, Grégory, Dessy, Francis J, Moris, Philippe, Lin, Lan, Struyf, Frank, Dubin, Gary

“…We previously reported higher anti-HPV-16 and -18 immune responses induced by HPV-16/18 vaccine compared with HPV-6/11/16/18 vaccine at Month 7 (one month…”
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Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D) by Agnandji, Selidji T, Fendel, Rolf, Mestré, Michaël, Janssens, Michel, Vekemans, Johan, Held, Jana, Gnansounou, Ferdinand, Haertle, Sonja, von Glasenapp, Isabel, Oyakhirome, Sunny, Mewono, Ludovic, Moris, Philippe, Lievens, Marc, Demoitie, Marie-Ange, Dubois, Patrice M, Villafana, Tonya, Jongert, Erik, Olivier, Aurelie, Cohen, Joe, Esen, Meral, Kremsner, Peter G, Lell, Bertrand, Mordmüller, Benjamin

“…The recombinant circumsporozoite protein (CS) based vaccine, RTS,S, confers protection against Plasmodium falciparum infection in controlled challenge trials…”
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Evaluation of the Safety and Immunogenicity of Two Antigen Concentrations of the Mtb72F/AS02A Candidate Tuberculosis Vaccine in Purified Protein Derivative-Negative Adults by Leroux-Roels, Isabel, Leroux-Roels, Geert, Ofori-Anyinam, Opokua, Moris, Philippe, De Kock, Els, Clement, Frederic, Dubois, Marie-Claude, Koutsoukos, Marguerite, Demoitie, Marie-Ange, Cohen, Joe, Ballou, WRipley

“…OA  Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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T cell responses to the RTS,S/AS01(E) and RTS,S/AS02(D) malaria candidate vaccines administered according to different schedules to Ghanaian children by Ansong, Daniel, Asante, Kwaku P, Vekemans, Johan, Owusu, Sandra K, Owusu, Ruth, Brobby, Naana A W, Dosoo, David, Osei-Akoto, Alex, Osei-Kwakye, Kingsley, Asafo-Adjei, Emmanuel, Boahen, Kwadwo O, Sylverken, Justice, Adjei, George, Sambian, David, Apanga, Stephen, Kayan, Kingsley, Janssens, Michel H, Lievens, Marc J J, Olivier, Aurelie C, Jongert, Erik, Dubois, Patrice, Savarese, Barbara M, Cohen, Joe, Antwi, Sampson, Greenwood, Brian M, Evans, Jennifer A, Agbenyega, Tsiri, Moris, Philippe J, Owusu-Agyei, Seth

“…The Plasmodium falciparum pre-erythrocytic stage candidate vaccine RTS,S is being developed for protection of young children against malaria in sub-Saharan…”
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Cell-mediated immune responses to different formulations of a live-attenuated tetravalent dengue vaccine candidate in subjects living in dengue endemic and non-endemic regions by Moris, Philippe, Bauer, Kristen M., Currier, Jeffrey R., Friberg, Heather, Eckels, Kenneth H., Esquilin, Ines O., Gibbons, Robert V., Innis, Bruce L., Jarman, Richard G., Simasathien, Sriluck, Sun, Peifang, Thomas, Stephen J., Watanaveeradej, Veerachai

“…Three phase II randomized trials evaluated the safety/immunogenicity of two formulations of live-attenuated tetravalent dengue virus (TDEN) vaccine in…”
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Circumsporozoite-specific T cell responses in children vaccinated with RTS,S/AS01E and protection against P falciparum clinical malaria by Olotu, Ally, Moris, Philippe, Mwacharo, Jedidah, Vekemans, Johan, Kimani, Domtila, Janssens, Michel, Kai, Oscar, Jongert, Erik, Lievens, Marc, Leach, Amanda, Villafana, Tonya, Savarese, Barbara, Marsh, Kevin, Cohen, Joe, Bejon, Philip

“…RTS,S/AS01(E) is the lead candidate pre-erythrocytic malaria vaccine. In Phase IIb field trials the safety profile was acceptable and the efficacy was 53%…”
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Early Gamma Interferon and Interleukin-2 Responses to Vaccination Predict the Late Resting Memory in Malaria-Naïve and Malaria-Exposed Individuals by Bejon, Philip, Keating, Sheila, Mwacharo, Jedidah, Kai, Oscar K, Dunachie, Susanna, Walther, Michael, Berthoud, Tamara, Lang, Trudie, Epstein, Judy, Carucci, Daniel, Moris, Philippe, Cohen, Joe, Gilbert, Sarah C, Peshu, Norbert, Marsh, Kevin, Hill, Adrian V.S

“…Two different cell populations respond to potent T-cell-inducing vaccinations. The induction and loss of effector cells can be seen using an ex vivo…”
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Early Gamma Interferon and Interleukin-2 Responses to Vaccination Predict the Late Resting Memory in Malaria-Naïve and Malaria-Exposed Individuals by Bejon, Philip, Keating, Sheila, Mwacharo, Jedidah, Kai, Oscar K., Dunachie, Susanna, Walther, Michael, Berthoud, Tamara, Lang, Trudie, Epstein, Judy, Carucci, Daniel, Moris, Philippe, Cohen, Joe, Gilbert, Sarah C., Peshu, Norbert, Marsh, Kevin, Hill, Adrian V. S.

“…ABSTRACT Two different cell populations respond to potent T-cell-inducing vaccinations. The induction and loss of effector cells can be seen using an ex vivo…”
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First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults by Cicconi, Paola, Jones, Claire, Sarkar, Esha, Silva-Reyes, Laura, Klenerman, Paul, de Lara, Catherine, Hutchings, Claire, Moris, Philippe, Janssens, Michel, Fissette, Laurence A, Picciolato, Marta, Leach, Amanda, Gonzalez-Lopez, Antonio, Dieussaert, Ilse, Snape, Matthew D

“…Respiratory syncytial virus (RSV) disease is a major cause of infant morbidity and mortality. This Phase I, randomized, observer-blind, placebo- and…”
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Safety and immunogenicity of candidate vaccine M72/AS01E in adolescents in a TB endemic setting by Penn-Nicholson, Adam, Geldenhuys, Hennie, Burny, Wivine, van der Most, Robbert, Day, Cheryl L, Jongert, Erik, Moris, Philippe, Hatherill, Mark, Ofori-Anyinam, Opokua, Hanekom, Willem, Bollaerts, Anne, Demoitie, Marie-Ange, Kany Luabeya, Angelique Kany, De Ruymaeker, Evi, Tameris, Michele, Lapierre, Didier, Scriba, Thomas J

“…Abstract Background Vaccination that prevents tuberculosis (TB) disease, particularly in adolescents, would have the greatest impact on the global TB epidemic…”
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Non-typeable Haemophilus influenzae protein vaccine in adults with COPD: A phase 2 clinical trial by Wilkinson, Tom M.A, Schembri, Stuart, Brightling, Christopher, Bakerly, Nawar D, Lewis, Keir, MacNee, William, Rombo, Lars, Hedner, Jan, Allen, Martin, Walker, Paul P, De Ryck, Iris, Tasciotti, Annaelisa, Casula, Daniela, Moris, Philippe, Testa, Marco, Arora, Ashwani K

“…Highlights•An investigational NTHi vaccine was tested for the first time in adults with COPD. •The vaccine had acceptable safety and reactogenicity…”
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