Search Results - "MORINO, KYUYA"

Trifluoromethoxy-benzylated ligands improve amyloid detection in the brain using (19)F magnetic resonance imaging by Amatsubo, Tomone, Morikawa, Shigehiro, Inubushi, Toshio, Urushitani, Makoto, Taguchi, Hiroyasu, Shirai, Nobuaki, Hirao, Koichi, Kato, Masanari, Morino, Kyuya, Kimura, Hirohiko, Nakano, Ichiro, Yoshida, Chikako, Okada, Takashi, Sano, Mitsuo, Tooyama, Ikuo

“…The chemical properties of probes that improve amyloid detection by non-invasive (19)F magnetic resonance imaging (MRI) are of interest. We synthesized…”
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Trifluoromethoxy-benzylated ligands improve amyloid detection in the brain using 19F magnetic resonance imaging by Amatsubo, Tomone, Morikawa, Shigehiro, Inubushi, Toshio, Urushitani, Makoto, Taguchi, Hiroyasu, Shirai, Nobuaki, Hirao, Koichi, Kato, Masanari, Morino, Kyuya, Kimura, Hirohiko, Nakano, Ichiro, Yoshida, Chikako, Okada, Takashi, Sano, Mitsuo, Tooyama, Ikuo

“…The chemical properties of probes that improve amyloid detection by non-invasive 19F magnetic resonance imaging (MRI) are of interest. We synthesized…”
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Relationship between the tautomeric structures of curcumin derivatives and their Aβ-binding activities in the context of therapies for Alzheimer's disease by Yanagisawa, Daijiro, Shirai, Nobuaki, Amatsubo, Tomone, Taguchi, Hiroyasu, Hirao, Koichi, Urushitani, Makoto, Morikawa, Shigehiro, Inubushi, Toshiro, Kato, Masanari, Kato, Fuminori, Morino, Kyuya, Kimura, Hirohiko, Nakano, Ichiro, Yoshida, Chikako, Okada, Takashi, Sano, Mitsuo, Wada, Yoshiko, Wada, Ken-nosuke, Yamamoto, Akitsugu, Tooyama, Ikuo

“…Abstract Curcumin, which can exist in an equilibrium between keto and enol tautomers, binds to β-amyloid (Aβ) fibrils/aggregates. The aim of this study was to…”
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Relationship between the tautomeric structures of curcumin derivatives and their Ab-binding activities in the context of therapies for Alzheimer's disease by Yanagisawa, Daijiro, Shirai, Nobuaki, Amatsubo, Tomone, Taguchi, Hiroyasu, Hirao, Koichi, Urushitani, Makoto, Morikawa, Shigehiro, Inubushi, Toshiro, Kato, Masanari, Kato, Fuminori, Morino, Kyuya, Kimura, Hirohiko, Nakano, Ichiro, Yoshida, Chikako, Okada, Takashi, Sano, Mitsuo, Wada, Yoshiko, Wada, Ken-nosuke, Yamamoto, Akitsugu, Tooyama, Ikuo

“…Curcumin, which can exist in an equilibrium between keto and enol tautomers, binds to b-amyloid (Ab) fibrils/aggregates. The aim of this study was to assess…”
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Binding form of curcumin derivatives to β-amyloid aggregates by Yanagisawa, Daijiro, Shirai, Nobuaki, Amatsubo, Tomone, Taguchi, Hiroyasu, Hirao, Koichi, Urushitani, Makoto, Morikawa, Shigehiro, Inubushi, Toshiro, Kato, Masanari, Morino, Kyuya, Kimura, Hirohiko, Nakano, Ichiro, Yoshida, Chikako, Okada, Takashi, Sano, Mitsuo, Tooyama, Ikuo

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P3‐007: Binding form of curcumin derivatives to β‐amyloid aggregates by Yanagisawa, Daijiro, Shirai, Nobuaki, Amatsubo, Tomone, Taguchi, Hiroyasu, Hirao, Koichi, Urushitani, Makoto, Morikawa, Shigehiro, Inubushi, Toshiro, Kato, Masanari, Morino, Kyuya, Kimura, Hirohiko, Nakano, Ichiro, Yoshida, Chikako, Okada, Takashi, Sano, Mitsuo, Tooyama, Ikuo

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Trifluoromethoxy-benzylated ligands improve amyloid detection in the brain using super(19)F magnetic resonance imaging by Amatsubo, Tomone, Morikawa, Shigehiro, Inubushi, Toshio, Urushitani, Makoto, Taguchi, Hiroyasu, Shirai, Nobuaki, Hirao, Koichi, Kato, Masanari, Morino, Kyuya, Kimura, Hirohiko, Nakano, Ichiro, Yoshida, Chikako, Okada, Takashi, Sano, Mitsuo, Tooyama, Ikuo

“…The chemical properties of probes that improve amyloid detection by non- invasive super(19)F magnetic resonance imaging (MRI) are of interest. We synthesized…”
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IC-P3-163: Interaction of the brain tissues with trifluoromethoxy-benzylated ligands for amyloid detection using 19F magnetic resonance imaging by Amatsubo, Tomone, Morikawa, Shigahiro, Matsuda, Keiko, Inubushi, Toshiro, Urushitani, Makoto, Taguchi, Hiroyasu, Shirai, Nobuaki, Hirao, Koichi, Kato, Masanari, Morino, Kyuya, Kimura, Hirohiko, Nakano, Ichiro, Yoshida, Chikako, Okada, Takashi, Sano, Mitsuo, Tooyama, Ikuo

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Effect of antihypertensive drugs on spinal neuronal activity in cats by Ikeda, Hironobu, Tsuchiyama, Michio, Ueda, Naoki, Morino, Kyuya, Nishimori, Tsukao

“…The relation of spinal neuronal activity (SNA) and blood pressure (BP) was investigated in cat spinal preparations, A spinal preparation (C1-C2 cut) was…”
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Relationship between the tautomeric structures of curcumin derivatives and their Abeta-binding activities in the context of therapies for Alzheimer's disease by Yanagisawa, Daijiro, Shirai, Nobuaki, Amatsubo, Tomone, Taguchi, Hiroyasu, Hirao, Koichi, Urushitani, Makoto, Morikawa, Shigehiro, Inubushi, Toshiro, Kato, Masanari, Kato, Fuminori, Morino, Kyuya, Kimura, Hirohiko, Nakano, Ichiro, Yoshida, Chikako, Okada, Takashi, Sano, Mitsuo, Wada, Yoshiko, Wada, Ken-nosuke, Yamamoto, Akitsugu, Tooyama, Ikuo

“…Curcumin, which can exist in an equilibrium between keto and enol tautomers, binds to beta-amyloid (Abeta) fibrils/aggregates. The aim of this study was to…”
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Effects of cadralazine on the central nervous system by Nishimori, T, Morino, K, Tsuchiyama, M, Ikeda, H, Hasegawa, K, Higashio, T, Akita, S, Yamauchi, T, Nakao, K, Inukai, T

“…The effect of cadralazine, a new antihypertensive agent, were studied on the central nervous systems in experimental animals. Oral administration of 0.5 mg/kg…”
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Mofezolac (N-22)の生殖・発生毒性試験(第2報) : ラット経口投与による胎仔器官形成期投与試験 by 迚野, 勲, 歯黒, 重樹, 古川, 茂典, 守永, 太賀彦, 森野, 久弥, 藤井, 重信, 山北, 修

“…被験物質N-22の10, 50, 100および150mg/kg/dayをラット母獣の妊娠7日目から17日目までの11日間にわたり毎日経口投与し, F0母獣, F1胎仔ならびにF1次世代動物におよぼす影響を検討するとともに一部の次世代動物を繁殖能試験に供してF2におよぼす影響についても検討した. 1…”
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GENERAL PHARMACOLOGICAL STUDY OF BRL 28500 by NISHIOKA, YOSHITAKA, KITAMURA, YUTAKA, ISHII, RYUTARO, KOSHIMA, YOSHINOBU, NISHIMORI, TSUKAO, KOBAYASHI, FUMIO, NISHIMURA, TAKAHARU, TSUCHIYAMA, MICHIO, MORINO, KYUYA, FLACK, JOHN D.

“…General pharmacological properties of BRL 28500 and its components CVA-K and TIPC were studied by administering these compounds intravenously. With regard to…”
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REPROUCTIVE AND DEVELOPMENTAL TOXICITY STUDY OF MOFEZOLAC (N-22) (2) : Study by Oral Administration of N-22 during the Period of Fetal Organogenesis in Rats by TOTENO, Isao, HAGURO, Sigeki, FURUKAWA, Shigenori, MORINAGA, Tagahiko, MORINO, Kyuya, FUJII, Shigenobu, YAMAKITA, Osamu

“…The teratogenicity of mofezolac (N-22), a new developed analgesic and anti-inflammatory agent, was investigated in rats. N-22 was given orally to pregnant rats…”
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REPROUCTIVE AND DEVELOPMENTAL TOXICITY STUDY OF MOFEZOLAC (N-22) (2) by TOTENO, Isao, HAGURO, Sigeki, FURUKAWA, Shigenori, MORINAGA, Tagahiko, MORINO, Kyuya, FUJII, Shigenobu, YAMAKITA, Osamu

“…The teratogenicity of mofezolac (N-22), a new developed analgesic and anti-inflammatory agent, was investigated in rats. N-22 was given orally to pregnant rats…”
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