Search Results - "MORIMOTO, YOKO"

The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells by Kikuchi, Kiyoshi, Kawahara, Ko-ichi, Tancharoen, Salunya, Matsuda, Fumiyo, Morimoto, Yoko, Ito, Takashi, Biswas, Kamal Krishna, Takenouchi, Kazunori, Miura, Naoki, Oyama, Yoko, Nawa, Yuko, Arimura, Noboru, Iwata, Masahiro, Tajima, Yutaka, Kuramoto, Terukazu, Nakayama, Kenji, Shigemori, Minoru, Yoshida, Yoshihiro, Hashiguchi, Teruto, Maruyama, Ikuro

“…Edaravone, a potent free radical scavenger, is clinically used for the treatment of cerebral infarction in Japan. Here, we examined the effects of edaravone on…”
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Beyond free radical scavenging: Beneficial effects of edaravone (Radicut) in various diseases (Review) by KIKUCHI, KIYOSHI, TAKESHIGE, NOBUYUKI, MIURA, NAOKI, MORIMOTO, YOKO, ITO, TAKASHI, TANCHAROEN, SALUNYA, MIYATA, KEI, KIKUCHI, CHIEMI, IIDA, NARUMI, UCHIKADO, HISAAKI, MIYAGI, NAOHISA, SHIOMI, NAOTO, KURAMOTO, TERUKAZU, MARUYAMA, IKURO, MORIOKA, MOTOHIRO, KAWAHARA, KO-ICHI

“…Free radicals play an important role in the pathogenesis of a variety of diseases; thus, they are an attractive target for therapeutic intervention in these…”
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MK615 attenuates Porphyromonas gingivalis lipopolysaccharide-induced pro-inflammatory cytokine release via MAPK inactivation in murine macrophage-like RAW264.7 cells by Morimoto, Yoko, Kikuchi, Kiyoshi, Ito, Takashi, Tokuda, Masayuki, Matsuyama, Takashi, Noma, Satoshi, Hashiguchi, Teruto, Torii, Mitsuo, Maruyama, Ikuro, Kawahara, Ko-ichi

“…The Japanese apricot, known as Ume in Japanese, has been a traditional Japanese medicine for centuries, and is a familiar and commonly consumed food. The…”
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Glycosylation and Malonylation of Quercetin, Epicatechin, and Catechin by Cultured Plant Cells by Shimoda, Kei, Otsuka, Takanao, Morimoto, Yoko, Hamada, Hatsuyuki, Hamada, Hiroki

“…Quercetin was converted to quercetin 3-O-(6-O-malonyl)-β-D-glucoside through the regioselective glucosylation at 3-position of quercetin and the following…”
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Potential of the angiotensin receptor blockers (ARBs) telmisartan, irbesartan, and candesartan for inhibiting the HMGB1/RAGE axis in prevention and acute treatment of stroke by Kikuchi, Kiyoshi, Tancharoen, Salunya, Ito, Takashi, Morimoto-Yamashita, Yoko, Miura, Naoki, Kawahara, Ko-ichi, Maruyama, Ikuro, Murai, Yoshinaka, Tanaka, Eiichiro

“…Stroke is a major cause of mortality and disability worldwide. The main cause of stroke is atherosclerosis, and the most common risk factor for atherosclerosis…”
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C-reactive protein induces high-mobility group box-1 protein release through activation of p38MAPK in macrophage RAW264.7 cells by Kawahara, Ko-ichi, Biswas, Kamal Krishna, Unoshima, Masako, Ito, Takashi, Kikuchi, Kiyoshi, Morimoto, Yoko, Iwata, Masahiro, Tancharoen, Salunya, Oyama, Yoko, Takenouchi, Kazunori, Nawa, Yuko, Arimura, Noboru, Jie, Meng Xiao, Shrestha, Binita, Miura, Naoki, Shimizu, Toshiaki, Mera, Kentaro, Arimura, Shin-ichiro, Taniguchi, Noboru, Iwasaka, Hideo, Takao, Sonshin, Hashiguchi, Teruto, Maruyama, Ikuro

“…Abstract Background C-reactive protein (CRP) is widely used as a sensitive biomarker for inflammation. Increasing evidence suggests that CRP plays a role in…”
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A natural therapeutic approach for the treatment of periodontitis by MK615 by Morimoto-Yamashita, Yoko, Kawakami, Yoshiko, Tatsuyama, Syoko, Miyashita, Keiko, Emoto, Makiko, Kikuchi, Kiyoshi, Kawahara, Ko-ichi, Tokuda, Masayuki

“…Abstract Periodontitis is a chronic inflammatory disease that affects the tooth-supporting tissues. Gingival fibroblasts are the most abundant cells in…”
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Edaravone: A new therapeutic approach for the treatment of acute stroke by Kikuchi, Kiyoshi, Kawahara, Ko-ichi, Miyagi, Naohisa, Uchikado, Hisaaki, Kuramoto, Terukazu, Morimoto, Yoko, Tancharoen, Salunya, Miura, Naoki, Takenouchi, Kazunori, Oyama, Yoko, Shrestha, Binita, Matsuda, Fumiyo, Yoshida, Yoshihiro, Arimura, Shinichiro, Mera, Kentaro, Tada, Ko-ichi, Yoshinaga, Narimasa, Maenosono, Ryuichi, Ohno, Yoshiko, Hashiguchi, Teruto, Maruyama, Ikuro, Shigemori, Minoru

“…Summary Acute stroke, including acute ischemic stroke (AIS) and acute hemorrhagic stroke, (AHS) is a common medical problem with particular relevance to the…”
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Edaravone, a Synthetic Free Radical Scavenger, Enhances Alteplase-Mediated Thrombolysis by Kikuchi, Kiyoshi, Setoyama, Kentaro, Kawahara, Ko-ichi, Nagasato, Tomoka, Terashi, Takuto, Ueda, Koki, Nakanishi, Kazuki, Otsuka, Shotaro, Miura, Naoki, Sameshima, Hisayo, Hosokawa, Kazuya, Harada, Yoichiro, Shrestha, Binita, Yamamoto, Mika, Morimoto-Yamashita, Yoko, Kikuchi, Haruna, Kiyama, Ryoji, Kamikokuryo, Chinatsu, Tancharoen, Salunya, Sakakima, Harutoshi, Morioka, Motohiro, Tanaka, Eiichiro, Ito, Takashi, Maruyama, Ikuro

“…The combination of alteplase, a recombinant tissue plasminogen activator, and edaravone, an antioxidant, reportedly enhances recanalization after acute…”
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HMGB1 as a therapeutic target in spinal cord injury: A hypothesis for novel therapy development by KIKUCHI, KIYOSHI, UCHIKADO, HISAAKI, MIURA, NAOKI, MORIMOTO, YOKO, ITO, TAKASHI, TANCHAROEN, SALUNYA, MIYATA, KEI, SAKAMOTO, ROKUDAI, KIKUCHI, CHIEMI, IIDA, NARUMI, SHIOMI, NAOTO, KURAMOTO, TERUKAZU, MIYAGI, NAOHISA, KAWAHARA, KO-ICHI

“…Historically, clinical outcomes following spinal cord injury (SCI) have been dismal. Severe SCI leads to devastating neurological deficits, and there is no…”
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Correction: Kikuchi, K., et al., Potential of the Angiotensin Receptor Blockers (ARBs) Telmisartan, Irbesartan, and Candesartan for Inhibiting the HMGB1/RAGE Axis in Prevention and Acute Treatment of Stroke. Int. J. Mol. Sci. 2013, 14, 18899–18924 by Kikuchi, Kiyoshi, Tancharoen, Salunya, Ito, Takashi, Morimoto-Yamashita, Yoko, Miura, Naoki, Kawahara, Ko-ichi, Maruyama, Ikuro, Murai, Yoshinaka, Tanaka, Eiichiro

“…The original version of the paper [1] reports that "This ACTIVE I study was supported by Pfizer" (Page 18905). However, the sponsors of the ACTIVE I study were…”
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Periodontal disease and type 2 diabetes mellitus: Is the HMGB1–RAGE axis the missing link? by Morimoto-Yamashita, Yoko, Ito, Takashi, Kawahara, Ko-ichi, Kikuchi, Kiyoshi, Tatsuyama-Nagayama, Shoko, Kawakami-Morizono, Yoshiko, Fijisawa, Mari, Miyashita, Keiko, Emoto, Makiko, Torii, Mitsuo, Tokuda, Masayuki

“…Abstract Periodontitis is a major chronic inflammatory disease associated with increased production of numerous proinflammatory cytokines, which leads to the…”
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Secondary prevention of stroke: Pleiotropic effects of optimal oral pharmacotherapy by KIKUCHI, KIYOSHI, KAWAHARA, KO-ICHI, MIURA, NAOKI, ITO, TAKASHI, MORIMOTO, YOKO, TANCHAROEN, SALUNYA, TAKESHIGE, NOBUYUKI, UCHIKADO, HISAAKI, SAKAMOTO, ROKUDAI, MIYAGI, NAOHISA, KIKUCHI, CHIEMI, IIDA, NARUMI, SHIOMI, NAOTO, KURAMOTO, TERUKAZU, HIROHATA, MASARU, MARUYAMA, IKURO, MORIOKA, MOTOHIRO, TANAKA, EIICHIRO

“…Stroke is a major cause of mortality and disability worldwide. During the past three decades, major advances have occurred in secondary prevention, which have…”
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Study of complement activation on well-defined surfaces using surface plasmon resonance by Hirata, Isao, Morimoto, Yoko, Murakami, Yoshinobu, Iwata, Hiroo, Kitano, Etsuko, Kitamura, Hajime, Ikada, Yoshito

“…It has been accepted that covalent immobilization of C3b on artificial materials is the most important step to initiate the complement activation. However,…”
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MK615: A new therapeutic approach for the treatment of oral disease by Morimoto-Yamashita, Yoko, Matsuo, Miki, Komatsuzawa, Hitoshi, Kawahara, Ko-ichi, Kikuchi, Kiyoshi, Torii, Mitsuo, Tokuda, Masayuki

“…Abstract The oral cavity is inhabited by over 500 different bacterial species. Dental caries and periodontitis are major bacterial infectious diseases in the…”
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Activation syndrome in the Japanese court by Muramatsu, Taro, Nakane, Jun, Morimoto, Yoko, Imai, Satoshi, Ohba, Hiroyuki

“…Since the February 2004 FDA advisory's warning of activation syndrome involving antidepressants, growing concerns have emerged over aggression and violence…”
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PET-detectable tau pathology correlates with long-term neuropsychiatric outcomes in patients with traumatic brain injury by Takahata, Keisuke, Kimura, Yasuyuki, Sahara, Naruhiko, Koga, Shunsuke, Shimada, Hitoshi, Ichise, Masanori, Saito, Fumie, Moriguchi, Sho, Kitamura, Soichiro, Kubota, Manabu, Umeda, Satoshi, Niwa, Fumitoshi, Mizushima, Jin, Morimoto, Yoko, Funayama, Michitaka, Tabuchi, Hajime, Bieniek, Kevin F, Kawamura, Kazunori, Zhang, Ming-Rong, Dickson, Dennis W, Mimura, Masaru, Kato, Motoichiro, Suhara, Tetsuya, Higuchi, Makoto

“…Tau deposits is a core feature of neurodegenerative disorder following traumatic brain injury (TBI). Despite ample evidence from post-mortem studies…”
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HMGB1: A new marker for estimation of the postmortem interval by KIKUCHI, KIYOSHI, KAWAHARA, KO-ICHI, BISWAS, KAMAL KRISHNA, ITO, TAKASHI, TANCHAROEN, SALUNYA, SHIOMI, NAOTO, KODA, YOSHIRO, MATSUDA, FUMIYO, MORIMOTO, YOKO, OYAMA, YOKO, TAKENOUCHI, KAZUNORI, MIURA, NAOKI, ARIMURA, NOBORU, NAWA, YUKO, ARIMURA, SHINICHIRO, JIE, MENG XIAO, SHRESTHA, BINITA, IWATA, MASAHIRO, MERA, KENTARO, SAMESHIMA, HISAYO, OHNO, YOSHIKO, MAENOSONO, RYUICHI, TAJIMA, YUTAKA, UCHIKADO, HISAAKI, KURAMOTO, TERUKAZU, NAKAYAMA, KENJI, SHIGEMORI, MINORU, YOSHIDA, YOSHIHIRO, HASHIGUCHI, TERUTO, MARUYAMA, IKURO

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Hyperosmotic Stress Induces Cell Death in an Odontoblast-lineage Cell Line by Fujisawa, Mari, DDS, Tokuda, Masayuki, DDS, PhD, Morimoto-Yamashita, Yoko, DDS, PhD, Tatsuyama, Shoko, DDS, PhD, Arany, Szilvia, DDS, PhD, Sugiyama, Toshihiro, MD, PhD, Kitamura, Chiaki, DDS, PhD, Shibukawa, Yoshiyuki, DDS, PhD, Torii, Mitsuo, DDS, PhD

“…Abstract Introduction Osmotic stress is one of the stimulations related to dental pain caused by caries or dentin hypersensitivity. The mechanism of…”
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729. Delayed-Onset Psychosis following TBI is Associated with Tau Depositions in the Neocortex but Not with β-Amyloid Depositions: A Pet Study with [11C]PBB3 and [11C]PiB by Takahata, Keisuke, Kimura, Yasuyuki, Shimada, Hitoshi, Ichise, Masanori, Tabuchi, Hajime, Kitamura, Soichiro, Kubota, Manabu, Moriguchi, Sho, Ishii, Tatsuya, Nina, Fumitoshi, End, Hironobu, Morimoto, Yoko, Funayama, Michitaka, Onaya, Matsumoto, Sahara, Naruhiko, Umeda, Satoshi, Mimura, Masaru, Higuchi, Makoto, Suhara, Tetsuya

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