Search Results - "MORIMOTO, Hajime"

Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury by KAWAGUCHI, Masanori, TAKAHASHI, Masafumi, HONGO, Minoru, NODA, Tetsuo, NAKAYAMA, Jun, SAGARA, Junji, TANIGUCHI, Shun'ichiro, IKEDA, Uichi, HATA, Takeki, KASHIMA, Yuichiro, USUI, Fumitake, MORIMOTO, Hajime, IZAWA, Atsushi, TAKAHASHI, Yasuko, MASUMOTO, Junya, KOYAMA, Jun

“…Background- Inflammation plays a key role in the pathophysiology of myocardial ischemia/reperfusion (I/R) injury; however, the mechanism by which myocardial…”
Get full text

Formation of Proton Motive Force Under Low-Aeration Alkaline Conditions in Alkaliphilic Bacteria by Matsuno, Toshihide, Goto, Toshitaka, Ogami, Shinichi, Morimoto, Hajime, Yamazaki, Koji, Inoue, Norio, Matsuyama, Hidetoshi, Yoshimune, Kazuaki, Yumoto, Isao

“…In Mitchell's chemiosmotic theory, a proton (H ) motive force across the membrane (Δp), generated by the respiratory chain, drives F F -ATPase for ATP…”
Get full text

Genome-wide analytical approaches using semi-quantitative expression proteomics for aromatic hydrocarbon metabolism in Pseudomonas putida F1 by Kasahara, Yasuhiro, Morimoto, Hajime, Kuwano, Masayoshi, Kadoya, Ryo

“…Pseudomonas putida F1 can degrade aromatic hydrocarbons to intermediate products of the tricarboxylic acid cycle. To determine key induced proteins and enzymes…”
Get full text

Cardiac Overexpression of Monocyte Chemoattractant Protein-1 in Transgenic Mice Prevents Cardiac Dysfunction and Remodeling After Myocardial Infarction by Morimoto, Hajime, Takahashi, Masafumi, Izawa, Atsushi, Ise, Hirohiko, Hongo, Minoru, Kolattukudy, Pappachan E, Ikeda, Uichi

“…Myocardial infarction (MI) is accompanied by inflammatory responses that lead to the recruitment of leukocytes and subsequent myocardial damage, healing, and…”
Get full text

Proteome analysis of Pseudomonas putida F1 genes induced in soil environments by Morimoto, Hajime, Kadoya, Ryosuke, Takahashi, Kazuhiro, Kasahara, Yasuhiro

“…Summary Knowledge of the gene expression dynamics of a single soil bacterial strain contributes to the understanding of its behaviour, physiological state and…”
Get full text

Contribution of intracellular negative ion capacity to Donnan effect across the membrane in alkaliphilic Bacillus spp by Goto, Toshitaka, Hirabayashi, Toshinao, Morimoto, Hajime, Yamazaki, Koji, Inoue, Norio, Matsuyama, Hidetoshi, Yumoto, Isao

“…To elucidate the energy production mechanism of alkaliphiles, the relationship between the H + extrusion rate by the respiratory chain and the corresponding…”
Get full text

Critical Role of Bone Marrow Apoptosis-Associated Speck-Like Protein, an Inflammasome Adaptor Molecule, in Neointimal Formation After Vascular Injury in Mice by YAJIMA, Noriyuki, TAKAHASHI, Masafumi, IKEDA, Uichi, MORIMOTO, Hajime, SHIBA, Yuji, TAKAHASHI, Yasuko, MASUMOTO, Junya, ISE, Hirohiko, SAGARA, Junji, NAKAYAMA, Jun, TANIGUCHI, Shunichiro

“…Inflammatory cytokines such as interleukin (IL)-1 beta and IL-18 play an important role in the development of atherosclerosis and restenosis…”
Get full text

Gene expression profiling of Pseudomonas putida F1 after exposure to aromatic hydrocarbon in soil by using proteome analysis by Morimoto, Hajime, Kuwano, Masayoshi, Kasahara, Yasuhiro

“…Pseudomonas putida F1 can metabolize toluene, ethylbenzene, and benzene for growth. Previously, we identified proteins involved in the utilization of these…”
Get full text

MCP-1 induces cardioprotection against ischaemia/reperfusion injury: role of reactive oxygen species by Morimoto, Hajime, Hirose, Masamichi, Takahashi, Masafumi, Kawaguchi, Masanori, Ise, Hirohiko, Kolattukudy, Pappachan E., Yamada, Mitsuhiko, Ikeda, Uichi

“…Aims Monocyte chemoattractant protein-1 (MCP-1: CCL2) has been demonstrated to be involved in the pathophysiology of ischaemic heart disease; however, the…”
Get full text

Critical role of Th17 cells in inflammation and neovascularization after ischaemia by HATA, Takeki, TAKAHASHI, Masafumi, IWAKURA, Yoichiro, TAKI, Shinsuke, IKEDA, Uichi, HIDA, Shigeaki, KAWAGUCHI, Masanori, KASHIMA, Yuichiro, USUI, Fumitake, MORIMOTO, Hajime, NISHIYAMA, Akiyo, IZAWA, Atsushi, KOYAMA, Jun

“…Increasing evidence suggests that CD4(+) T cells contribute to neovascularization in ischaemic tissue. However, the T cell subset responsible for…”
Get full text

Bone marrow CXCR4 induction by cultivation enhances therapeutic angiogenesis by Shiba, Yuji, Takahashi, Masafumi, Hata, Takeki, Murayama, Hideki, Morimoto, Hajime, Ise, Hirohiko, Nagasawa, Takashi, Ikeda, Uichi

“…Aims The chemokine stromal cell-derived factor-1 (SDF-1) and its receptor (CXCR4, CXC chemokine receptor 4) play a critical role in the process of post-natal…”
Get full text

Bone Marrow-Derived CXCR4+ Cells Mobilized by Macrophage Colony-Stimulating Factor Participate in the Reduction of Infarct Area and Improvement of Cardiac Remodeling after Myocardial Infarction in Mice by Morimoto, Hajime, Takahashi, Masafumi, Shiba, Yuji, Izawa, Atsushi, Ise, Hirohiko, Hongo, Minoru, Hatake, Kiyohiko, Motoyoshi, Kazuo, Ikeda, Uichi

“…The monocyte/macrophage lineage might affect the healing process after myocardial infarction (MI). Because macrophage colony-stimulating factor (M-CSF)…”
Get full text

Effective uptake of N-acetylglucosamine-conjugated liposomes by cardiomyocytes in vitro by Aso, Shin-ichi, Ise, Hirohiko, Takahashi, Masafumi, Kobayashi, Satoshi, Morimoto, Hajime, Izawa, Atsushi, Goto, Mitsuaki, Ikeda, Uichi

“…A drug delivery system (DDS) that targets the injured myocardium would serve as a novel therapeutic tool for cardiac diseases. To develop such a DDS, we…”
Get full text

Mycophenolate mofetil attenuates pulmonary arterial hypertension in rats by Suzuki, Chihiro, Takahashi, Masafumi, Morimoto, Hajime, Izawa, Atsushi, Ise, Hirohiko, Hongo, Minoru, Hoshikawa, Yasushi, Ito, Takayuki, Miyashita, Hiroshi, Kobayashi, Eiji, Shimada, Kazuyuki, Ikeda, Uichi

“…Pulmonary arterial hypertension (PAH) is characterized by abnormal proliferation of smooth muscle cells (SMCs), leading to occlusion of pulmonary arterioles,…”
Get full text

Mycophenolate mofetil prevents the development of experimental autoimmune myocarditis by Kamiyoshi, Yuichi, Takahashi, Masafumi, Yokoseki, Osamu, Yazaki, Yoshikazu, Hirose, Sho-ichi, Morimoto, Hajime, Watanabe, Noboru, Kinoshita, Osamu, Hongo, Minoru, Ikeda, Uichi

“…Experimental autoimmune myocarditis (EAM) is characterized by the appearance of multinucleated giant cells. EAM leads to severe myocardial damage and is a…”
Get full text

Therapeutic potential of endothelial progenitor cells for cardiovascular diseases by Jia, Lijing, Takahashi, Masafumi, Yoshioka, Toru, Morimoto, Hajime, Ise, Hirohiko, Ikeda, Uichi

“…In the past decade, researchers have defined committed stem or progenitor cells from various tissues, including bone marrow, peripheral blood, brain, liver and…”
Get more information

Erythropoietin attenuates the development of experimental autoimmune myocarditis by HIROSE, Sho-Ichi, TAKAHASHI, Masafumi, OGAWA, Ryo, MORIMOTO, Hajime, IZAWA, Atsushi, SATO, Hajime, ISE, Hirohiko, HONGO, Minoru, IKEDA, Uichi

“…Erythropoietin (EPO) has been shown to not only have cardioprotective effects but also attenuate autoimmune diseases. In the present study, we investigated the…”
Get full text

Role of monocyte chemoattractant protein-1 in myocardial infarction by Morimoto, Hajime, Takahashi, Masafumi

“…Myocardial infarction (MI) is accompanied by inflammatory responses that lead to the recruitment of leukocytes and subsequent myocardial damage, healing, and…”
Get full text

M-CSF Accelerates Neointimal Formation in the Early Phase After Vascular Injury in Mice: The Critical Role of the SDF-1–CXCR4 System by Shiba, Yuji, Takahashi, Masafumi, Yoshioka, Toru, Yajima, Noriyuki, Morimoto, Hajime, Izawa, Atsushi, Ise, Hirohiko, Hatake, Kiyohiko, Motoyoshi, Kazuo, Ikeda, Uichi

“…OBJECTIVE—Since the macrophage colony-stimulating factor (M-CSF) has been shown to stimulate differentiation and proliferation of monocyte/macrophage lineage…”
Get full text

Relationship between rates of respiratory proton extrusion and ATP synthesis in obligately alkaliphilic Bacillus clarkii DSM 8720(T) by Hirabayashi, Toshikazu, Goto, Toshitaka, Morimoto, Hajime, Yoshimune, Kazuaki, Matsuyama, Hidetoshi, Yumoto, Isao

“…To elucidate the energy production mechanism of alkaliphiles, the relationship between the rate of proton extrusion via the respiratory chain and the…”
Get full text