Search Results - "MORII, Takashi"

A Bioorganic Chemistry Approach to Understanding Molecular Recognition in Protein–Nucleic Acid Complexes by Morii, Takashi

“…A combination of synthetic, organic, and biochemical approaches has been developed to study how protein and nucleic acid assemblies modulate the affinity,…”
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Spatially Organized Enzymes Drive Cofactor-Coupled Cascade Reactions by Ngo, Tien Anh, Nakata, Eiji, Saimura, Masayuki, Morii, Takashi

“…We report the construction of an artificial enzyme cascade based on the xylose metabolic pathway. Two enzymes, xylose reductase and xylitol dehydrogenase, were…”
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Nucleic‐Acid‐Templated Enzyme Cascades by Rajendran, Arivazhagan, Nakata, Eiji, Nakano, Shun, Morii, Takashi

“…Cellular metabolism involves complex sequences of organized enzymatic reactions, known as metabolic pathways, that convert substrates into readily usable…”
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Mechanistic Aspects for the Modulation of Enzyme Reactions on the DNA Scaffold by Lin, Peng, Yang, Hui, Nakata, Eiji, Morii, Takashi

“…Cells have developed intelligent systems to implement the complex and efficient enzyme cascade reactions via the strategies of organelles, bacterial…”
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Stimuli-Responsible SNARF Derivatives as a Latent Ratiometric Fluorescent Probe by Nakata, Eiji, Gerelbaatar, Khongorzul, Komatsubara, Futa, Morii, Takashi

“…Fluorescence imaging is a powerful technique for continuous observation of dynamic intracellular processes of living cells. Fluorescent probes bearing a…”
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Controlled Assembly of Fluorophores inside a Nanoliposome by Konishi, Hiroaki, Nakata, Eiji, Komatsubara, Futa, Morii, Takashi

“…Cellular compartmentalization plays an essential role in organizing the complex and multiple biochemical reactions in the cell. An artificial compartment would…”
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Validating subcellular thermal changes revealed by fluorescent thermosensors by Kiyonaka, Shigeki, Sakaguchi, Reiko, Hamachi, Itaru, Morii, Takashi, Yoshizaki, Takenao, Mori, Yasuo

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Design of Modular Protein Tags for Orthogonal Covalent Bond Formation at Specific DNA Sequences by Nguyen, Thang Minh, Nakata, Eiji, Saimura, Masayuki, Dinh, Huyen, Morii, Takashi

“…Simultaneous formation of specific covalent linkages at nucleotides in given DNA sequences demand distinct orthogonal reactivity of DNA modification agents…”
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Genetically encoded fluorescent thermosensors visualize subcellular thermoregulation in living cells by Kiyonaka, Shigeki, Kajimoto, Taketoshi, Sakaguchi, Reiko, Shinmi, Daisuke, Omatsu-Kanbe, Mariko, Matsuura, Hiroshi, Imamura, Hiromi, Yoshizaki, Takenao, Hamachi, Itaru, Morii, Takashi, Mori, Yasuo

“…Genetically encoded sensors based on GFP enable the visualization of subcellular thermal changes noninvasively in intact cells. In mammals and birds,…”
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Topologically‐Interlocked Minicircles as Probes of DNA Topology and DNA‐Protein Interactions by Rajendran, Arivazhagan, Krishnamurthy, Kirankumar, Park, Seojeong, Nakata, Eiji, Kwon, Youngjoo, Morii, Takashi

“…DNA minicircles exist in biological contexts, such as kinetoplast DNA, and are promising components for creating functional nanodevices. They have been used to…”
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Tuning the Reactivity of a Substrate for SNAP‐Tag Expands Its Application for Recognition‐Driven DNA‐Protein Conjugation by Zhang, Zhengxiao, Nakata, Eiji, Dinh, Huyen, Saimura, Masayuki, Rajendran, Arivazhagan, Matsuda, Kazunari, Morii, Takashi

“…Recognition‐driven modification has been emerging as a novel approach to modifying biomolecular targets of interest site‐specifically and efficiently. To this…”
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Topologically‐Interlocked Minicircles as Probes of DNA Topology and DNA–Protein Interactions by Rajendran, Arivazhagan, Krishnamurthy, Kirankumar, Park, Seojeong, Nakata, Eiji, Kwon, Youngjoo, Morii, Takashi

“…Invited for the cover of this issue are Prof. Takashi Morii and co‐workers at Kyoto University and Ewha Womans University. The cover image depicts the…”
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Enhanced enzymatic activity exerted by a packed assembly of a single type of enzyme by Dinh, Huyen, Nakata, Eiji, Mutsuda-Zapater, Kaori, Saimura, Masayuki, Kinoshita, Masahiro, Morii, Takashi

“…In contrast to the dilute conditions employed for in vitro biochemical studies, enzymes are spatially organized at high density in cellular micro-compartments…”
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Zinc-Finger Proteins for Site-Specific Protein Positioning on DNA-Origami Structures by Nakata, Eiji, Liew, Fong Fong, Uwatoko, Chisana, Kiyonaka, Shigeki, Mori, Yasuo, Katsuda, Yousuke, Endo, Masayuki, Sugiyama, Hiroshi, Morii, Takashi

“…Point the finger: Zinc‐finger proteins are convenient and site‐selective adaptors for targeting specific locations within DNA‐origami structures. Orthogonal…”
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Nanometer Accuracy in Cryogenic Far-Field Localization Microscopy of Individual Molecules by Furubayashi, Taku, Ishida, Keita, Kashida, Hiromu, Nakata, Eiji, Morii, Takashi, Matsushita, Michio, Fujiyoshi, Satoru

“…We demonstrate the nanometer accuracy of far-field fluorescence localization microscopy at a temperature of 1.8 K using near-infrared and red fluorophores…”
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Reaction of ribulose biphosphate carboxylase/oxygenase assembled on a DNA scaffold by Dinh, Huyen, Nakata, Eiji, Lin, Peng, Saimura, Masayuki, Ashida, Hiroki, Morii, Takashi

“…Ribulose-1,5-biphosphate carboxylase/oxygenase (RuBisCO), an enzyme in the Calvin-Benson-Bassham cycle of photosynthesis, catalyzes the first step of CO2…”
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A modular zinc finger adaptor accelerates the covalent linkage of proteins at specific locations on DNA nanoscaffolds by Nakata, Eiji, Dinh, Huyen, Ngo, Tien Anh, Saimura, Masayuki, Morii, Takashi

“…A modular adaptor consisting of a sequence-specific DNA binding zinc finger protein and a self-ligating protein-tag was developed to expedite efficient…”
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DNA Origami Scaffolds as Templates for Functional Tetrameric Kir3 K+ Channels by Kurokawa, Tatsuki, Kiyonaka, Shigeki, Nakata, Eiji, Endo, Masayuki, Koyama, Shohei, Mori, Emiko, Tran, Nam Ha, Dinh, Huyen, Suzuki, Yuki, Hidaka, Kumi, Kawata, Masaaki, Sato, Chikara, Sugiyama, Hiroshi, Morii, Takashi, Mori, Yasuo

“…In native systems, scaffolding proteins play important roles in assembling proteins into complexes to transduce signals. This concept is yet to be applied to…”
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Simultaneous Detection of ATP and GTP by Covalently Linked Fluorescent Ribonucleopeptide Sensors by Nakano, Shun, Fukuda, Masatora, Tamura, Tomoki, Sakaguchi, Reiko, Nakata, Eiji, Morii, Takashi

“…A noncovalent RNA complex embedding an aptamer function and a fluorophore-labeled peptide affords a fluorescent ribonucleopeptide (RNP) framework for…”
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Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound by Kiyonaka, Shigeki, Kato, Kenta, Nishida, Motohiro, Mio, Kazuhiro, Numaga, Takuro, Sawaguchi, Yuichi, Yoshida, Takashi, Wakamori, Minoru, Mori, Emiko, Numata, Tomohiro, Ishii, Masakazu, Takemoto, Hiroki, Ojida, Akio, Watanabe, Kenta, Uemura, Aya, Kurose, Hitoshi, Morii, Takashi, Kobayashi, Tsutomu, Sato, Yoji, Sato, Chikara, Hamachi, Itaru, Mori, Yasuo

“…Canonical transient receptor potential (TRPC) channels control influxes of Ca²⁺ and other cations that induce diverse cellular processes upon stimulation of…”
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