A case of pelvic malignant paraganglioma

A case of pelvic malignant paraganglioma

We report a rare case of pelvic malignant paraganglioma that was treated with surgery, combination chemotherapy and radiation. A 47‐year‐old man was diagnosed with pelvic malignant paraganglioma that had metastasised to the thoracic vertebrae. The pelvic mass, which was 6 cm in size, was on the post...

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Bibliographic Details
Published in:International journal of urology Vol. 8; no. 12; pp. 715 - 718
Main Authors: TAUE, RYUICHI, TAKIGAWA, HIROSHI, SINOTOU, KENJI, UNO, SATOSHI, MORI, RYOUJI, TATARA, KIYOSHI, SANO, TOSHIAKI
Format: Journal Article
Language:English
Published: Melbourne, Australia Blackwell Science Asia Pty. Ltd 01-12-2001
Subjects:
Antineoplastic Combined Chemotherapy Protocols
Combined Modality Therapy
CVD chemotherapy
Cyclophosphamide - administration & dosage
Dacarbazine - administration & dosage
Etoposide - administration & dosage
Humans
Magnetic Resonance Imaging
Male
malignant paraganglioma
Middle Aged
Paraganglioma - diagnosis
Paraganglioma - radiotherapy
Paraganglioma - surgery
Paraganglioma - therapy
Pelvic Neoplasms - diagnosis
Pelvic Neoplasms - diagnostic imaging
Pelvic Neoplasms - surgery
Pelvic Neoplasms - therapy
Radionuclide Imaging
Vincristine - administration & dosage
VP-16
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Summary:We report a rare case of pelvic malignant paraganglioma that was treated with surgery, combination chemotherapy and radiation. A 47‐year‐old man was diagnosed with pelvic malignant paraganglioma that had metastasised to the thoracic vertebrae. The pelvic mass, which was 6 cm in size, was on the posterior side of the bladder and had invaded the prostate, seminal vesicle and bladder neck. We resected the intrapelvic tumor and lymph nodes using cystoprostatectomy. Metastases to bilateral obturator lymph nodes and the right internal iliac lymph node were shown by pathology. Adjuvant therapies included six courses of the combination chemotherapy (cyclophosphamide, vincristine and dacarbazine), and 12 courses of VP‐16 therapy. Radiation therapy was done for metastasis of the thoracic vertebrae. Local recurrence, progression of bone metastasis and new metastasis have not been detected since these treatments. The patient has been clinically stable during 20 months of follow‐up. Chemotherapy of cyclophosphamide, vincristine and dacarbazine and VP‐16 with radiation appears to be effective in treating advanced malignant paraganglioma.
Bibliography:istex:5BDC23A23E60AC96CBD558C842DE9EB76B176646
ark:/67375/WNG-BZFXPLQV-J
ArticleID:IJU406
ISSN:0919-8172
1442-2042
DOI:10.1046/j.1442-2042.2001.00406.x