Search Results - "MORI, JUN"

Anti‐tumor efficacy of human anti‐c‐met CAR‐T cells against papillary renal cell carcinoma in an orthotopic model by Mori, Jun‐ich, Adachi, Keishi, Sakoda, Yukimi, Sasaki, Takahiro, Goto, Shunsuke, Matsumoto, Hiroaki, Nagashima, Yoji, Matsuyama, Hideyasu, Tamada, Koji

“…Chimeric antigen receptor (CAR)‐T cell therapy has shown salient efficacy in cancer immunotherapy, particularly in the treatment of B cell malignancies…”
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Src family kinases: at the forefront of platelet activation by Senis, Yotis A., Mazharian, Alexandra, Mori, Jun

“…Src family kinases (SFKs) play a central role in mediating the rapid response of platelets to vascular injury. They transmit activation signals from a diverse…”
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ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity by Patel, Vaibhav B, Mori, Jun, McLean, Brent A, Basu, Ratnadeep, Das, Subhash K, Ramprasath, Tharmarajan, Parajuli, Nirmal, Penninger, Josef M, Grant, Maria B, Lopaschuk, Gary D, Oudit, Gavin Y

“…Obesity is increasing in prevalence and is strongly associated with metabolic and cardiovascular disorders. The renin-angiotensin system (RAS) has emerged as a…”
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ACE2 exerts anti-obesity effect via stimulating brown adipose tissue and induction of browning in white adipose tissue by Kawabe, Yasuhiro, Mori, Jun, Morimoto, Hidechika, Yamaguchi, Mihoko, Miyagaki, Satoshi, Ota, Takeshi, Tsuma, Yusuke, Fukuhara, Shota, Nakajima, Hisakazu, Oudit, Gavin Y, Hosoi, Hajime

“…The angiotensin II (ANG II)-ANG II type 1 receptor (AT R) axis is a key player in the pathophysiology of obesity. Angiotensin-converting enzyme 2 (ACE2)…”
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Clinical and molecular analyses of isolated central congenital hypothyroidism based on a survey conducted in Japan by Shibata, Nao, Numakura, Chikahiko, Hamajima, Takashi, Miyako, Kenichi, Fujiwara, Ikuma, Mori, Jun, Saitoh, Akihiko, Nagasaki, Keisuke

“…Central congenital hypothyroidism (CH) can occur as an isolated deficiency or as part of combined pituitary hormone deficiency. Unlike primary CH, central CH…”
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Vitamin A deficiency manifested as conjunctival hyperemia due to a limited food repertoire by Kawase, Izumi, Mori, Jun, Yokoi, Norihiko

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ANG II causes insulin resistance and induces cardiac metabolic switch and inefficiency: a critical role of PDK4 by Mori, Jun, Alrob, Osama Abo, Wagg, Cory S, Harris, Robert A, Lopaschuk, Gary D, Oudit, Gavin Y

“…The renin-angiotensin system (RAS) may alter cardiac energy metabolism in heart failure. Angiotensin II (ANG II), the main effector of the RAS in heart…”
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Alfacalcidol improves the growth velocity in children with vitamin D deficiency/insufficiency: A single center retrospective cohort study by Miyagaki, Satoshi, Yamaguchi, Mihoko, Ota, Takeshi, Kawabe, Yasuhiro, Morimoto, Hidechika, Oka, Yoshinobu, Mori, Jun

“…To investigate the growth velocity-improving effects of vitamin D replacement therapy in pediatric patients diagnosed with vitamin D deficiency and…”
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Angiotensin 1-7 stimulates brown adipose tissue and reduces diet-induced obesity by Morimoto, Hidechika, Mori, Jun, Nakajima, Hisakazu, Kawabe, Yasuhiro, Tsuma, Yusuke, Fukuhara, Shota, Kodo, Kazuki, Ikoma, Kazuya, Matoba, Satoaki, Oudit, Gavin Y, Hosoi, Hajime

“…The renin-angiotensin system is a key regulator of metabolism with beneficial effects of the angiotensin 1-7 (Ang 1-7) peptide. We hypothesized that the…”
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Snap diagnosis of fulminant type 1 diabetes by the normalized glucose/HbA1c ratio by Mori, Jun-Ichiro, Miyakoshi, Takahiro, Yuzuriha, Hanae, Kondo, Teruki, Nishimori, Eita, Naka, Motoji, Sato, Ai, Komatsu, Mitsuhisa, Yamashita, Koh, Aizawa, Toru

“…Elevated Fulminant Index (FI), [plasma glucose (PG)/glycosylated hemoglobin A1c (HbA1c)], was reportedly a sensitive index to differentiate fulminant type 1…”
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Tobacco Price Increase and Smoking Cessation in Japan, a Developed Country With Affordable Tobacco: A National Population-Based Observational Study by Tabuchi, Takahiro, Nakamura, Masakazu, Nakayama, Tomio, Miyashiro, Isao, Mori, Jun-Ichiro, Tsukuma, Hideaki

“…Longitudinal assessment of the impact of tobacco price on smoking cessation is scarce. Our objective was to investigate the effect of a price increase in…”
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Partially Hydrolyzed Guar Gum Suppresses the Development of Sarcopenic Obesity by Okamura, Takuro, Hamaguchi, Masahide, Mori, Jun, Yamaguchi, Mihoko, Mizushima, Katsura, Abe, Aya, Ozeki, Makoto, Sasano, Ryoichi, Naito, Yuji, Fukui, Michiaki

“…Partially hydrolyzed guar gum (PHGG) is a soluble dietary fiber derived through controlled enzymatic hydrolysis of guar gum, a highly viscous galactomannan…”
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CLEC-2 expression is maintained on activated platelets and on platelet microparticles by Gitz, Eelo, Pollitt, Alice Y., Gitz-Francois, Jerney J., Alshehri, Osama, Mori, Jun, Montague, Samantha, Nash, Gerard B., Douglas, Michael R., Gardiner, Elizabeth E., Andrews, Robert K., Buckley, Christopher D., Harrison, Paul, Watson, Steve P.

“…The C-type lectin-like receptor CLEC-2 mediates platelet activation through a hem-immunoreceptor tyrosine-based activation motif (hemITAM). CLEC-2 initiates a…”
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Klinefelter syndrome in an adolescent with severe obesity, insulin resistance, and hyperlipidemia, successfully treated with testosterone replacement therapy by Fukuhara, Shota, Mori, Jun, Nakajima, Hisakazu

“…Klinefelter syndrome (KS) is a sex chromosome disorder characterized by the presence of one or more extra X chromosomes. KS is well known by the common…”
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A case of diffuse congenital hyperinsulinism in which continuous glucose monitoring contributed to the choice of a treatment strategy following a subtotal pancreatectomy by Zukeran, Hiroaki, Akiba, Kazuhisa, Higuchi, Shinji, Mori, Jun, Yorifuji, Tohru, Hasegawa, Yukihiro

“…Patients with diffuse congenital hyperinsulinism (CHI) refractory to drug therapy require subtotal or near-total pancreatectomy. Although almost all patients…”
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Impact of the renin–angiotensin system on cardiac energy metabolism in heart failure by Mori, Jun, Zhang, Liyan, Oudit, Gavin Y, Lopaschuk, Gary D

“…Abstract The renin–angiotensin system (RAS) plays a key pathogenic role in heart failure. The adverse effects of angiotensin II (Ang II), a major player of the…”
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Strength⁻Durability Correlation of Osteosynthesis Devices Made by 3D Layer Manufacturing by Okazaki, Yoshimitsu, Gotoh, Emiko, Mori, Jun

“…To develop orthopedic implants that are optimized for each patient's needs or skeletal structure (custom-made implants), evaluations of the bending strength,…”
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Erythropoietin (EPO) ameliorates obesity and glucose homeostasis by promoting thermogenesis and endocrine function of classical brown adipose tissue (BAT) in diet-induced obese mice by Kodo, Kazuki, Sugimoto, Satoru, Nakajima, Hisakazu, Mori, Jun, Itoh, Ikuyo, Fukuhara, Shota, Shigehara, Keiichi, Nishikawa, Taichiro, Kosaka, Kitaro, Hosoi, Hajime

“…Erythropoietin (EPO), clinically used as a hematopoietic drug, has received much attention due to its nonhematopoietic effects. EPO reportedly has beneficial…”
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Targeted gene panel analysis of Japanese patients with maturity‐onset diabetes of the young‐like diabetes mellitus: Roles of inactivating variants in the ABCC8 and insulin resistance genes by Yorifuji, Tohru, Watanabe, Yoh, Kitayama, Kana, Yamada, Yuki, Higuchi, Shinji, Mori, Jun, Kato, Masaru, Takahashi, Toru, Okuda, Tokuko, Aoyama, Takane

“…Aims/Introduction To investigate the genetic background of Japanese patients with suspected maturity‐onset diabetes of the young (MODY). Materials and Methods…”
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Cleidocranial dysplasia with growth hormone deficiency: a case report by Takaki, Nozomi, Mori, Jun, Matsuo, Satoshi, Osamura, Toshio, Michigami, Toshimi

“…Cleidocranial dysplasia (CCD) is a rare skeletal disorder with autosomal dominant inheritance that is characterized by hypoplastic clavicles, delayed closure…”
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