Search Results - "MORI, Hirotada"
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Extensive impact of non-antibiotic drugs on human gut bacteria
Published in Nature (London) (29-03-2018)“…A few commonly used non-antibiotic drugs have recently been associated with changes in gut microbiome composition, but the extent of this phenomenon is…”
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2
Bacterial persisters are a stochastically formed subpopulation of low-energy cells
Published in PLoS biology (19-04-2021)“…Persisters represent a small subpopulation of non- or slow-growing bacterial cells that are tolerant to killing by antibiotics. Despite their prominent role in…”
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3
Genetically stable kill-switch using "demon and angel" expression construct of essential genes
Published in Frontiers in bioengineering and biotechnology (28-02-2024)“…Genetic instability of synthetic genetic devices is a key obstacle for practical use. This problem is particularly critical in kill-switches for conditional…”
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4
Glycerol-derived reuterin regulates human intestinal microbiota and metabolites
Published in Frontiers in microbiology (18-10-2024)“…Reuterin, a mixture of different forms of 3-hydroxypropanal (3-HPA), including HPA hydrate and HPA dimer, is an antimicrobial compound converted from glycerol…”
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5
In vitro membrane protein synthesis inside Sec translocon-reconstituted cell-sized liposomes
Published in Scientific reports (03-11-2016)“…Protein synthesis using an in vitro transcription-translation system (IVTT) inside cell-sized liposomes has become a valuable tool to study the properties of…”
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6
Unprecedented high-resolution view of bacterial operon architecture revealed by RNA sequencing
Published in mBio (08-07-2014)“…We analyzed the transcriptome of Escherichia coli K-12 by strand-specific RNA sequencing at single-nucleotide resolution during steady-state…”
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7
Update of thermotolerant genes essential for survival at a critical high temperature in Escherichia coli
Published in PloS one (27-02-2018)“…Previous screening of a single-gene knockout library consisting of 3,908 disrupted-mutant strains allowed us to identify 51 thermotolerant genes that are…”
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8
Past, Present, and Future of Genome Modification in Escherichia coli
Published in Microorganisms (Basel) (14-09-2022)“…K-12 is one of the most well-studied species of bacteria. This species, however, is much more difficult to modify by homologous recombination (HR) than other…”
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9
Genome-Wide Screening of Genes Required for Swarming Motility in Escherichia coli K-12
Published in Journal of Bacteriology (01-02-2007)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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10
Genome-Wide Screening with Hydroxyurea Reveals a Link between Nonessential Ribosomal Proteins and Reactive Oxygen Species Production
Published in Journal of Bacteriology (01-03-2013)“…We performed a screening of hydroxyurea (HU)-sensitive mutants using a single-gene-deletion mutant collection in Escherichia coli. HU inhibits ribonucleotide…”
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11
Comprehensive identification of translation start sites by tetracycline-inhibited ribosome profiling
Published in DNA research (01-06-2016)“…Tetracycline-inhibited ribosome profiling (TetRP) provides a powerful new experimental tool for comprehensive genome-wide identification of translation…”
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12
Optimization of RK2-based gene introduction system for Bacillus subtilis
Published in Journal of general and applied microbiology (01-01-2019)“…The Gram-positive bacterium Bacillus subtilis plays important roles in both industrial applications and basic research. However, transformation of competent B…”
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13
Systematic phenome analysis of Escherichia coli multiple-knockout mutants reveals hidden reactions in central carbon metabolism
Published in Molecular systems biology (15-09-2009)“…Central carbon metabolism is a basic and exhaustively analyzed pathway. However, the intrinsic robustness of the pathway might still conceal uncharacterized…”
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14
Effect of codon adaptation on codon-level and gene-level translation efficiency in vivo
Published in BMC genomics (16-12-2014)“…There is a significant difference between synonymous codon usage in many organisms, and it is known that codons used more frequently generally showed efficient…”
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15
Update on the Keio collection of Escherichia coli single-gene deletion mutants
Published in Molecular systems biology (22-12-2009)Get full text
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16
Combinatorial selection for replicable RNA by Qβ replicase while maintaining encoded gene function
Published in PloS one (22-03-2017)“…Construction of a complex artificial self-replication system is challenging in the field of in vitro synthetic biology. Recently, we developed a…”
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17
Two‐component system VraSR positively modulates the regulation of cell‐wall biosynthesis pathway in Staphylococcus aureus
Published in Molecular microbiology (01-08-2003)“…Summary DNA microarray covering the whole genome of Staphylococcus aureus strain N315 was prepared to investigate transcription profiles. The microarray…”
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18
Accumulation of heme biosynthetic intermediates contributes to the antibacterial action of the metalloid tellurite
Published in Nature communications (11-05-2017)“…The metalloid tellurite is highly toxic to microorganisms. Several mechanisms of action have been proposed, including thiol depletion and generation of…”
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Evolved bacterial resistance against fluoropyrimidines can lower chemotherapy impact in the Caenorhabditis elegans host
Published in eLife (30-11-2020)“…Metabolism of host-targeted drugs by the microbiome can substantially impact host treatment success. However, since many host-targeted drugs inadvertently…”
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Genetic mutation in Escherichia coli genome during adaptation to the murine intestine is optimized for the host diet
Published in mSystems (20-02-2024)“…The gut microbiota is closely associated with human health and is greatly impacted by the host diet. Bacteria such as live in the gut all throughout the life…”
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