Search Results - "MORI, HISASHI"
-
1
BST1 regulates nicotinamide riboside metabolism via its glycohydrolase and base-exchange activities
Published in Nature communications (19-11-2021)“…Nicotinamide riboside (NR) is one of the orally bioavailable NAD + precursors and has been demonstrated to exhibit beneficial effects against aging and…”
Get full text
Journal Article -
2
Complex Processes Underlying the Dynamic Changes of D-serine Levels in AD Brains
Published in Current Alzheimer research (01-01-2022)“…Alzheimer's disease (AD) is a neurodegenerative disorder characterized by extracellular β-amyloid (Aβ) plaques and cognitive impairments. D-Serine, produced by…”
Get more information
Journal Article -
3
A new bioluminescence-based tool for modulating target proteins in live cells
Published in Scientific reports (03-12-2019)“…We have developed a new genetically encoded tool designed to generate reactive oxygen species (ROS) at target proteins in cultured cells; it is designed using…”
Get full text
Journal Article -
4
Serine racemase is involved in d-aspartate biosynthesis
Published in Journal of biochemistry (Tokyo) (01-12-2016)“…d-Aspartate is found in the nervous and reproductive system and participates in various physiological roles. While several lines of evidence suggest that this…”
Get full text
Journal Article -
5
Blockade of D-serine signaling and adult hippocampal neurogenesis attenuates remote contextual fear memory following multiple memory retrievals in male mice
Published in Frontiers in neuroscience (04-01-2023)“…The retrieval of fear memories induces two opposing processes, reconsolidation, and extinction. The memory reconsolidation is an active process that involves…”
Get full text
Journal Article -
6
CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors
Published in Nature communications (18-08-2017)“…Adipose tissue resident macrophages have important roles in the maintenance of tissue homeostasis and regulate insulin sensitivity for example by secreting…”
Get full text
Journal Article -
7
Fabrication of free-standing GaN substrates using electrochemically formed porous separation layers
Published in Applied physics express (01-05-2024)“…Abstract We have developed a pore-assisted separation (PAS) method for the fabrication of free-standing GaN substrates, where bulk GaN crystals were separated…”
Get full text
Journal Article -
8
Control of actin polymerization via reactive oxygen species generation using light or radiation
Published in Frontiers in cell and developmental biology (23-09-2022)“…Actin is one of the most prevalent proteins in cells, and its amino acid sequence is remarkably conserved from protozoa to humans. The…”
Get full text
Journal Article -
9
Correction: Glucocorticoid receptor-mediated amygdalar metaplasticity underlies adaptive modulation of fear memory by stress
Published in eLife (26-09-2024)Get full text
Journal Article -
10
The Relationship between 24 h Ultramarathon Performance and the “Big Three” Strategies of Training, Nutrition, and Pacing
Published in Sports (Basel) (01-10-2022)“…Background: The present case study examined the relationship between 24 h ultramarathon performance and the “big three” strategies of training, nutrition, and…”
Get full text
Journal Article -
11
Bioluminescence imaging using d -luciferin and its analogs for visualizing Bdnf expression in living mice; different patterns of bioluminescence signals using distinct luciferase substrates
Published in Journal of biochemistry (Tokyo) (01-11-2022)“…Abstract Brain-derived neurotrophic factor (BDNF) plays a crucial role in numerous brain functions, including memory consolidation. Previously, we generated a…”
Get full text
Journal Article -
12
Mice lacking BCAS1, a novel myelin‐associated protein, display hypomyelination, schizophrenia‐like abnormal behaviors, and upregulation of inflammatory genes in the brain
Published in Glia (01-05-2017)“…The abnormal expression and function of myelin‐related proteins contribute to nervous system dysfunction associated with neuropsychiatric disorders; however,…”
Get full text
Journal Article -
13
Anti-NMDAR autoimmune encephalitis
Published in Brain & development (Tokyo. 1979) (01-09-2014)“…Abstract The N -methyl- d -aspartate receptor (NMDAR) is involved in normal physiological and pathological states in the brain. Anti-NMDAR encephalitis is…”
Get full text
Journal Article -
14
Vascular PDGFR-alpha protects against BBB dysfunction after stroke in mice
Published in Angiogenesis (London) (01-02-2021)“…Blood–brain barrier (BBB) dysfunction underlies the pathogenesis of many neurological diseases. Platelet-derived growth factor receptor-alpha (PDGFRα) induces…”
Get full text
Journal Article -
15
Personalized heart rate management through data-driven dynamic exercise control
Published in Scientific reports (27-07-2024)“…Maximizing healthy life expectancy is essential for enhancing well-being. Optimal exercise intensity is crucial in promoting health and ensuring safe…”
Get full text
Journal Article -
16
Neuronal D-serine and glycine release via the Asc-1 transporter regulates NMDA receptor-dependent synaptic activity
Published in The Journal of neuroscience (20-02-2013)“…D-Serine and glycine are coagonists of NMDA receptors (NMDARs), but their relative contributions for several NMDAR-dependent processes are unclear. We now…”
Get full text
Journal Article -
17
Structural insights into selective interaction between type IIa receptor protein tyrosine phosphatases and Liprin-α
Published in Nature communications (31-01-2020)“…Synapse formation is induced by transsynaptic interaction of neuronal cell-adhesion molecules termed synaptic organizers. Type IIa receptor protein tyrosine…”
Get full text
Journal Article -
18
Depletion of CD206+ M2-like macrophages induces fibro-adipogenic progenitors activation and muscle regeneration
Published in Nature communications (21-11-2022)“…Muscle regeneration requires the coordination of muscle stem cells, mesenchymal fibro-adipogenic progenitors (FAPs), and macrophages. How macrophages regulate…”
Get full text
Journal Article -
19
In Vivo Depletion of CD206+ M2 Macrophages Exaggerates Lung Injury in Endotoxemic Mice
Published in The American journal of pathology (2015)“…Although phenotypically polarized macrophages are now generally classified into two major subtypes termed proinflammatory M1 and anti-inflammatory M2…”
Get full text
Journal Article -
20
Zinc Transporter SLC39A7/ZIP7 Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress
Published in PLoS genetics (13-10-2016)“…Zinc transporters play a critical role in spatiotemporal regulation of zinc homeostasis. Although disruption of zinc homeostasis has been implicated in…”
Get full text
Journal Article