Search Results - "MORGAN, Matthew D"

Fifteen-Year Survival of Endoscopic Anterior Cruciate Ligament Reconstruction in Patients Aged 18 Years and Younger by Morgan, Matthew D., Salmon, Lucy J., Waller, Alison, Roe, Justin P., Pinczewski, Leo A.

“…Background: The current body of literature surrounding anterior cruciate ligament (ACL) survival and the variables contributing to further ACL injuries after…”
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Rituximab versus Cyclophosphamide in ANCA-Associated Renal Vasculitis by Jones, Rachel B, Cohen Tervaert, Jan Willem, Hauser, Thomas, Luqmani, Raashid, Morgan, Matthew D, Peh, Chen Au, Savage, Caroline O, Segelmark, Mårten, Tesar, Vladimir, van Paassen, Pieter, Walsh, Michael, Walsh, Dorothy, Westman, Kerstin, Jayne, David R.W

“…A standard glucocorticoid regimen plus rituximab was not superior to standard intravenous cyclophosphamide as induction therapy in patients with newly…”
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Pulse versus daily oral cyclophosphamide for induction of remission in ANCA-associated vasculitis: long-term follow-up by Harper, Lorraine, Morgan, Matthew D, Walsh, Michael, Hoglund, Peter, Westman, Kerstin, Flossmann, Oliver, Tesar, Vladimir, Vanhille, Phillipe, de Groot, Kirsten, Luqmani, Raashid, Flores-Suarez, Luis Felipe, Watts, Richard, Pusey, Charles, Bruchfeld, Annette, Rasmussen, Niels, Blockmans, Daniel, Savage, Caroline O, Jayne, David

“…The previously reported randomised controlled trial of a consensus regimen of pulse cyclophosphamide suggested that it was as effective as a daily oral (DO)…”
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The host cellular immune response to cytomegalovirus targets the endothelium and is associated with increased arterial stiffness in ANCA-associated vasculitis by Chanouzas, Dimitrios, Sagmeister, Michael, Dyall, Lovesh, Sharp, Phoebe, Powley, Lucy, Johal, Serena, Bowen, Jessica, Nightingale, Peter, Ferro, Charles J, Morgan, Matthew D, Moss, Paul, Harper, Lorraine

“…Cardiovascular disease is a leading cause of death in ANCA-associated vasculitis (AAV). An expansion of CD4 CD28 T cells is seen mainly in cytomegalovirus…”
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Prediction of ESRD and Death Among People With CKD: The Chronic Renal Impairment in Birmingham (CRIB) Prospective Cohort Study by Landray, Martin J., PhD, FRCP, Emberson, Jonathan R., PhD, Blackwell, Lisa, BSc, Dasgupta, Tanaji, MRCP, Zakeri, Rosita, MRCP, Morgan, Matthew D., MRCP, PhD, Ferro, Charlie J., BSc, MD, FRCP, Vickery, Susan, MSc, PhD, Ayrton, Puja, MSc, MRCP, MRCPath, Nair, Devaki, MSc, FRCPath, Dalton, R. Neil, MA, PhD, Lamb, Edmund J., PhD, FRCPath, Baigent, Colin, MSc, FRCP, Townend, Jonathan N., MD, FRCP, Wheeler, David C., MD, FRCP

“…Background Validated prediction scores are required to assess the risks of end-stage renal disease (ESRD) and death in individuals with chronic kidney disease…”
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Rituximab for treatment of severe renal disease in ANCA associated vasculitis by Geetha, Duvuru, Hruskova, Zdenka, Segelmark, Marten, Hogan, Jonathan, Morgan, Matthew D., Cavero, Teresa, Eriksson, Per, Seo, Philip, Manno, Rebecca L., Dale, Jessica, Harper, Lorraine, Tesar, Vladimir, Jayne, David RW

“…Background Rituximab (RTX) is approved for remission induction in ANCA associated vasculitis (AAV). However, data on use of RTX in patients with severe renal…”
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Humoral immunity to memory antigens and pathogens is maintained in patients with chronic kidney disease by Wall, Nadezhda A, Dominguez-Medina, C Coral, Faustini, Sian E, Cook, Charlotte N, McClean, Andrew, Jesky, Mark D, Perez-Toledo, Marisol, Morgan, Matthew D, Richter, Alexandra G, Ferro, Charles J, Cockwell, Paul, Moss, Paul A, Henderson, Ian R, Harper, Lorraine, Cunningham, Adam F

“…Patients with chronic kidney disease (CKD) have an increased risk of infection and poorer responses to vaccination. This suggests that CKD patients have an…”
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Pathogenesis of ANCA-associated Vasculitis by Flint, Julia, MBBS, Morgan, Matthew D., MRCP, PhD, Savage, Caroline O.S., FRCP, FMedSci

“…Antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) comprises a group of systemic inflammatory vasculitides associated with circulating…”
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ANCA induces β2 integrin and CXC chemokine-dependent neutrophil-endothelial cell interactions that mimic those of highly cytokine-activated endothelium by Calderwood, Judith W., Williams, Julie M., Morgan, Matthew D., Nash, Gerard B., Savage, Caroline O. S.

“…Antineutrophil cytoplasm antibodies (ANCA) activate neutrophils to undergo a series of coordinated interactions, leading to transendothelial migration,…”
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Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis: 2-year results of a randomised trial by Jones, Rachel B, Furuta, Shunsuke, Tervaert, Jan Willem Cohen, Hauser, Thomas, Luqmani, Raashid, Morgan, Matthew D, Peh, Chen Au, Savage, Caroline O, Segelmark, Marten, Tesar, Vladimir, van Paassen, Pieter, Walsh, Michael, Westman, Kerstin, Jayne, David Rw

“…The RITUXVAS trial reported similar remission induction rates and safety between rituximab and cyclophosphamide based regimens for antineutrophil cytoplasm…”
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The Longitudinal Course of Fatigue in Antineutrophil Cytoplasmic Antibody-associated Vasculitis by O'Malley, Lucy, Druce, Katie L, Chanouzas, Dimitrios, Morgan, Matthew D, Jones, Rachel, Jayne, David R W, Basu, Neil, Harper, Lorraine

“…Fatigue is common and burdensome in antineutrophil cytoplasmic antibody-associated vasculitis (AAV). This study aimed to understand how fatigue changes over…”
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Management of fatigue with physical activity and behavioural change support in vasculitis: a feasibility study by Harper, Lorraine, Hewitt, Catherine A, Litchfield, Ian, Morgan, Matthew D, Chanouzas, Dimitrios, Caulfield, Hollie K, Coughlan, Linda, Dean, Caroline, Fletcher, Kate, Cramp, Fiona, Greenfield, Sheila, Ives, Natalie J, Jowett, Sue, Kodabuckus, Shalela, Tearne, Sarah, Sehmi, Sukhwant, Edwardson, Charlotte, Dawkins, Nathan P, Daley, Amanda J

“…Abstract Objective Patients with ANCA-associated vasculitis (AAV) experience high levels of fatigue, despite disease remission. This study assessed the…”
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Physical Fatigue, Fitness, and Muscle Function in Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis by McClean, Andrew, Morgan, Matthew D., Basu, Neil, Bosch, Jos A., Nightingale, Peter, Jones, David, Harper, Lorraine

“…Objective This study investigated differences in cardiorespiratory fitness, muscular function, perceived exertion, and anxiety/depression between patients and…”
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Patients with Wegener’s granulomatosis demonstrate a relative deficiency and functional impairment of T‐regulatory cells by Morgan, Matthew D., Day, Clara J., Piper, Karen P., Khan, Naeem, Harper, Lorraine, Moss, Paul A., Savage, Caroline O. S.

“…Summary An increased proportion of CD4+ CD25+ T cells has been reported in Wegener’s granulomatosis (WG) and may represent an accumulation of regulatory T…”
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Successful outcome of pregnancy in patients with anti-neutrophil cytoplasm antibody-associated small vessel vasculitis by Croft, Adam P, Smith, Stuart W, Carr, Sue, Youssouf, Sajeda, Salama, Alan D, Burns, Aine, Pusey, Charles D, Hamilton, Patrick, Brown, Nina, Venning, Michael, Harper, Lorraine, Morgan, Matthew D

“…Pregnancy in patients with anti-neutrophil cytoplasm antibody-associated vasculitis is reportedly associated with a high risk of fetal and maternal…”
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Treatment of severe renal disease in ANCA positive and negative small vessel vasculitis with rituximab by Shah, Shivani, Hruskova, Zdenka, Segelmark, Marten, Morgan, Matthew D, Hogan, Jonathan, Lee, Steven K, Dale, Jessica, Harper, Lorraine, Tesar, Vladimir, Jayne, David R W, Geetha, Duvuru

“…Rituximab and glucocorticoids are a non-inferior alternative to cyclophosphamide and glucocorticoid therapy for induction of remission in antineutrophil…”
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CD4+CD28− T cell expansion in granulomatosis with polyangiitis (Wegener's) is driven by latent cytomegalovirus infection and is associated with an increased risk of infection and mortality by Morgan, Matthew D., Pachnio, Annette, Begum, Jusnara, Roberts, David, Rasmussen, Niels, Neil, Desley A. H., Bajema, Ingeborg, Savage, Caroline O. S., Moss, Paul A., Harper, Lorraine

“…Objective Expanded populations of CD4+CD28− T cells with a cytotoxic phenotype have been repeatedly reported in patients with granulomatosis with polyangiitis…”
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Addition of infliximab to standard therapy for ANCA-associated vasculitis by Morgan, Matthew D, Drayson, Mark T, Savage, Caroline O S, Harper, Lorraine

“…Tumour necrosis factor-α (TNF) is implicated in the pathogenesis of anti-neutrophil cytoplasm antibody-associated vasculitis (AAV). Current immunosuppressive…”
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Elevated active secretory sphingomyelinase in antineutrophil cytoplasmic antibody-associated primary systemic vasculitis by Kiprianos, Allan P, Morgan, Matthew D, Little, Mark A, Harper, Lorraine, Bacon, Paul A, Young, Stephen P

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T Lymphocyte Responses to Nonpolymorphic HLA-Derived Peptides Are Associated With Chronic Renal Allograft Dysfunction by SMITH, Helen J, HANVESAKUL, Rajesh, BENTALL, Andrew, SHABIR, Shazia, MORGAN, Matthew D, BRIGGS, David, COCKWELL, Paul, BORROWS, Richard, LARCHE, Mark, BALL, Simon

“…The routine assessment of cellular alloimmunity to guide therapy is of perennial interest because this limb of the immune system is the main target of current…”
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