Search Results - "MOREY, James V"

Direct ortho Cupration:  A New Route to Regioselectively Functionalized Aromatics by Usui, Shinya, Hashimoto, Yuichi, Morey, James V, Wheatley, Andrew E. H, Uchiyama, Masanobu

“…We have developed a direct regio- and chemoselective method for generating functionalized aromatic cuprate compounds through deprotonative directed ortho…”
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An Aluminum Ate Base:  Its Design, Structure, Function, and Reaction Mechanism by Naka, Hiroshi, Uchiyama, Masanobu, Matsumoto, Yotaro, Wheatley, Andrew E. H, McPartlin, Mary, Morey, James V, Kondo, Yoshinori

“…An aluminum ate base, i-Bu3Al(TMP)Li, has been designed and developed for regio- and chemoselective direct generation of functionalized aromatic aluminum…”
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On the Kinetic and Thermodynamic Reactivity of Lithium Di(alkyl)amidozincate Bases in Directed Ortho Metalation by Kondo, Yoshinori, Morey, James V, Morgan, Jacqueline C, Naka, Hiroshi, Nobuto, Daisuke, Raithby, Paul R, Uchiyama, Masanobu, Wheatley, Andrew E. H

“…Sequential reaction of HTMP (= 2,2,6,6-tetramethylpiperidine) with n BuLi and Et2Zn affords unsolvated polymer chains of EtZn(μ-Et)(μ-TMP)Li 6. The scope of…”
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The Selenium-Based Hexameric Macrocycle [(Se)P(μ-NtBu)2P(μ-Se)]6 by González-Calera, Silvia, Eisler, Dana J., Morey, James V., McPartlin, Mary, Singh, Sanjay, Wright, Dominic S.

“…Head‐to‐Tail: The Wurtz reaction of the dimer [(Cl)(Se)P(μ‐NtBu)]2 (1) with sodium metal gives the inorganic macrocycle [(Se)P(μ‐NtBu)2P(μ‐Se)]6 (2), arising…”
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Trapping of Oligomeric Cyclopentadienyllithium Cationic and Anionic Fragments by a V[triple chemical bond]V-Bonded Ligand by Fernández-Cortabitarte, Cecilia, García, Felipe, Morey, James V, McPartlin, Mary, Singh, Sanjay, Wheatley, Andrew E.H, Wright, Dominic S

“…Breaking up: The first triple‐decker sandwich anion [(η5‐Cp)Li(η5‐Cp)Li(η5‐Cp)]− of lithocene (Cp=C5H5) (observed in the charge‐separated complex…”
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Mixed Alkylamido Aluminate as a Kinetically Controlled Base by Naka, Hiroshi, Morey, James V, Haywood, Joanna, Eisler, Dana J, McPartlin, Mary, García, Felipe, Kudo, Hironaga, Kondo, Yoshinori, Uchiyama, Masanobu, Wheatley, Andrew E. H

“…The mechanisms by which directed ortho metalation (DoM) and postmetalation processes occur when aromatic compounds are treated with mixed alkylamido aluminate…”
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Selenium-Based Hexameric Macrocycle [(Se==)P(μ-NtBu)₂P(μ-Se)] by González-Calera, Silvia, Eisler, Dana J, Morey, James V, McPartlin, Mary, Singh, Sanjay, Wright, Dominic S

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The discovery of 2-amino-3,5-diarylbenzamide inhibitors of IKK-α and IKK-β kinases by Christopher, John A., Avitabile, Barbara G., Bamborough, Paul, Champigny, Aurelie C., Cutler, Geoffrey J., Dyos, Susan L., Grace, Ken G., Kerns, Jeffrey K., Kitson, Jeremy D., Mellor, Geoffrey W., Morey, James V., Morse, Mary A., O’Malley, Carolyn F., Patel, Champa B., Probst, Nicholas, Rumsey, William, Smith, Clive A., Wilson, Michael J.

“…A potent and selective series of 2-amino-3,5-diarylbenzamide inhibitors of IKK-α and IKK-β is described. The most potent compounds are 8h, 8r and 8v, with…”
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3,5-Disubstituted-indole-7-carboxamides: The discovery of a novel series of potent, selective inhibitors of IKK-β by Miller, David D., Bamborough, Paul, Christopher, John A., Baldwin, Ian R., Champigny, Aurelie C., Cutler, Geoffrey J., Kerns, Jeffrey K., Longstaff, Timothy, Mellor, Geoffrey W., Morey, James V., Morse, Mary A., Nie, Hong, Rumsey, William L., Taggart, John J.

“…The discovery and hit-to-lead exploration of a novel series of selective IKK-β kinase inhibitors is described. The initial lead fragment 3 was identified by…”
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5-(1 H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-ε kinase by Bamborough, Paul, Christopher, John A., Cutler, Geoffrey J., Dickson, Marion C., Mellor, Geoffrey W., Morey, James V., Patel, Champa B., Shewchuk, Lisa M.

“…The identification and hit-to-lead exploration of a novel, potent, and selective series of substituted benzimidazole-thiophene carbonitrile inhibitors of IKK-…”
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Suppressing the Anionic Fries Rearrangement of Aryl Dialkylcarbamates; the Isolation of a Crystalline ortho-Deprotonated Carbamate by García, Felipe, McPartlin, Mary, Morey, James V., Nobuto, Daisuke, Kondo, Yoshinori, Naka, Hiroshi, Uchiyama, Masanobu, Wheatley, Andrew E. H.

“…In the presence of organolithium bases phenyl dialkylcarbamates have previously been shown to undergo facile rearrangement to yield the corresponding…”
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Gilman-Type versus Lipshutz-Type Reagents: Competition in Lithiocuprate Chemistry by Haywood, Joanna, Morey, James V, Wheatley, Andrew E. H, Liu, Ching-Yuan, Yasuike, Shuji, Kurita, Jyoji, Uchiyama, Masanobu, Raithby, Paul R

“…CuCN reacts with RLi and TMPLi (TMP = 2,2,6,6-tetramethylpiperidide) to give Gilman-type cuprates R(TMP)CuLi·nL (R = Ph, n = 3, L = THF 2; R = Me, n = 1, L =…”
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The synthesis and single-crystal X-ray structures of palladium(II) and platinum(II) complexes of the difluorovinyl and 1-chloro-2-fluorovinyl-substituted phosphines, PPh2(Z-CFCFH) and PPh2(E-CClCFH) by Barnes, Nicholas A., Brisdon, Alan K., Fish, Cheryl, Morey, James V., Pritchard, Robin G., Warren, John E.

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The synthesis and single-crystal X-ray structures of palladium(II) and platinum(II) complexes of the difluorovinyl and 1-chloro-2-fluorovinyl-substituted phosphines, PPh sub(2)(Z-CF[inline image]CFH) and PPh sub(2)(E-CCl[inline image]CFH) by Barnes, Nicholas A, Brisdon, Alan K, Fish, Cheryl, Morey, James V, Pritchard, Robin G, Warren, John E

“…The coordination chemistry of the fluorovinyl substituted phosphines PPh sub(2)(Z-CF[inline image]CFH) and PPh sub(2)(E-CCl[inline image]CFH) with K sub(2)MX…”
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3,5-Disubstituted-indole-7-carboxamides: The discovery of a novel series of potent, selective inhibitors of IIK-β by MILLER, David D, BAMBOROUGH, Paul, MORSE, Mary A, HONG NIE, RUMSEY, William L, TAGGART, John J, CHRISTOPHER, John A, BALDWIN, Ian R, CHAMPIGNY, Aurelie C, CUTLER, Geoffrey J, KERNS, Jeffrey K, LONGSTAFF, Timothy, MELLOR, Geoffrey W, MOREY, James V

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The synthesis and single-crystal X-ray structures of palladium(II) and platinum(II) complexes of the difluorovinyl and 1-chloro-2-fluorovinyl-substituted phosphines, PPh 2( Z-CF CFH) and PPh 2( E-CCl CFH) by Barnes, Nicholas A., Brisdon, Alan K., Fish, Cheryl, Morey, James V., Pritchard, Robin G., Warren, John E.

“…The synthesis of a series of Pd(II) and Pt(II) complexes of partially fluorinated ligands of the type Ph 2P(CX CFH) (X = F, Cl) are reported. A comparison of…”
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The Selenium-Based Hexameric Macrocycle [(Se)P(μ-NtBu)2P(μ-Se)]6 by González-Calera, Silvia, Eisler, Dana J., Morey, James V., McPartlin, Mary, Singh, Sanjay, Wright, Dominic S.

“…Kopf‐Schwanz‐Verknüpfung: Die Wurtz‐Reaktion des Dimers [(Cl)(Se)P(μ‐NtBu)]2 (1) mit Natrium führt über ein intermediäres Selen‐Nucleophil zum anorganischen…”
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Trapping of Oligomeric Cyclopentadienyllithium Cationic and Anionic Fragments by a VV-Bonded Ligand by Fernández-Cortabitarte, Cecilia, García, Felipe, Morey, James V., McPartlin, Mary, Singh, Sanjay, Wheatley, Andrew E. H., Wright, Dominic S.

“…Aufbruch‐Stimmung: Das erste Tripeldecker‐Sandwichanion [(η5‐Cp)Li(η5‐Cp)Li(η5‐Cp)]− von Lithocen (Cp=C5H5) entsteht bei der Reaktion von [Cp2V] mit hppLi…”
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The Selenium‐Based Hexameric Macrocycle [(Se)P(μ‐N t Bu) 2 P(μ‐Se)] 6 by González‐Calera, Silvia, Eisler, Dana J., Morey, James V., McPartlin, Mary, Singh, Sanjay, Wright, Dominic S.

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Trapping of Oligomeric Cyclopentadienyllithium Cationic and Anionic Fragments by a VV‐Bonded Ligand by Fernández‐Cortabitarte, Cecilia, García, Felipe, Morey, James V., McPartlin, Mary, Singh, Sanjay, Wheatley, Andrew E. H., Wright, Dominic S.

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