Search Results - "MORENO, Carol"

First-line treatment of chronic lymphocytic leukemia with ibrutinib plus obinutuzumab versus chlorambucil plus obinutuzumab: final analysis of the randomized, phase III iLLUMINATE trial by Moreno, Carol, Greil, Richard, Demirkan, Fatih, Tedeschi, Alessandra, Anz, Bertrand, Larratt, Loree, Simkovic, Martin, Novak, Jan, Strugov, Vladimir, Gill, Devinder, Gribben, John G, Kwei, Kevin, Dai, Sandra, Hsu, Emily, Dean, James P, Flinn, Ian W

“…iLLUMINATE is a randomized, open-label phase III study of ibrutinib plus obinutuzumab (n=113) versus chlorambucil plus obinutuzumab (n=116) as first-line…”
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Long-term follow-up of the RESONATE phase 3 trial of ibrutinib vs ofatumumab by Byrd, John C., Hillmen, Peter, O'Brien, Susan, Barrientos, Jacqueline C., Reddy, Nishitha M., Coutre, Steven, Tam, Constantine S., Mulligan, Stephen P., Jaeger, Ulrich, Barr, Paul M., Furman, Richard R., Kipps, Thomas J., Thornton, Patrick, Moreno, Carol, Montillo, Marco, Pagel, John M., Burger, Jan A., Woyach, Jennifer A., Dai, Sandra, Vezan, Remus, James, Danelle F., Brown, Jennifer R.

“…Ibrutinib, a once-daily oral inhibitor of Bruton tyrosine kinase, has greatly improved outcomes for patients with chronic lymphocytic leukemia (CLL). The phase…”
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Sustained efficacy and detailed clinical follow-up of first-line ibrutinib treatment in older patients with chronic lymphocytic leukemia: extended phase 3 results from RESONATE-2 by Barr, Paul M, Robak, Tadeusz, Owen, Carolyn, Tedeschi, Alessandra, Bairey, Osnat, Bartlett, Nancy L, Burger, Jan A, Hillmen, Peter, Coutre, Steven, Devereux, Stephen, Grosicki, Sebastian, McCarthy, Helen, Li, Jianyong, Simpson, David, Offner, Fritz, Moreno, Carol, Zhou, Cathy, Styles, Lori, James, Danelle, Kipps, Thomas J, Ghia, Paolo

“…Results of RESONATE-2 (PCYC-1115/1116) supported approval of ibrutinib for first-line treatment of chronic lymphocytic leukemia. Extended analysis of…”
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Characteristics, Symptom Severity, and Experiences of Patients Reporting Chronic Kidney Disease in the PatientsLikeMe Online Health Community: Retrospective and Qualitative Study by James, Glen, Nyman, Elisabeth, Fitz-Randolph, Marcy, Niklasson, Anna, Hedman, Katarina, Hedberg, Jonatan, Wittbrodt, Eric T, Medin, Jennie, Moreno Quinn, Carol, Allum, Alaster M, Emmas, Cathy

“…Chronic kidney disease (CKD) is a major global health burden, and is associated with increased adverse outcomes, poor quality of life, and substantial health…”
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Rituximab plus bendamustine or chlorambucil for chronic lymphocytic leukemia: primary analysis of the randomized, open-label MABLE study by Michallet, Anne-Sophie, Aktan, Melih, Hiddemann, Wolfgang, Ilhan, Osman, Johansson, Peter, Laribi, Kamel, Meddeb, Balkis, Moreno, Carol, Raposo, João, Schuh, Anna, Ünal, Ali, Widenius, Tom, Bernhardt, Alf, Kellershohn, Kerstin, Messeri, Dimitri, Osborne, Stuart, Leblond, Véronique

“…MABLE investigated the efficacy and safety of rituximab plus bendamustine or rituximab plus chlorambucil in fludarabine-ineligible patients with chronic…”
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Chronic lymphocytic leukemia and autoimmunity: a systematic review by HODGSON, Kate, FERRER, Gerardo, MONTSERRAT, Emili, MORENO, Carol

“…Chronic lymphocytic leukemia is frequently associated with immune disturbances. The relationship between chronic lymphocytic leukemia and autoimmune…”
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Effects of Patiromer and Sodium Zirconium Cyclosilicate on Blood Pressure in Rats with Chronic Kidney Disease by Li, Lingyun, Budden, Jeff, Quinn, Carol Moreno, Bushinsky, David

“…Potassium-binders patiromer and sodium zirconium cyclosilicate (SZC) are approved to treat hyperkalaemia, which is frequently observed in chronic kidney…”
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Autoimmune cytopenia in chronic lymphocytic leukemia: prevalence, clinical associations, and prognostic significance by Moreno, Carol, Hodgson, Kate, Ferrer, Gerardo, Elena, Montse, Filella, Xavier, Pereira, Arturo, Baumann, Tycho, Montserrat, Emili

“…We analyzed prevalence, characteristics, clinical correlates, and prognostic significance of autoimmune cytopenia in patients with chronic lymphocytic…”
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Restoration of the immune function as a complementary strategy to treat Chronic Lymphocytic Leukemia effectively by Moreno, Carol, Muñoz, Cecilia, Terol, María José, Hernández-Rivas, José-Ángel, Villanueva, Miguel

“…Chronic Lymphocytic Leukemia (CLL) is a hematological malignancy characterized by uncontrolled proliferation of B-cells and severe immune dysfunction…”
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Identifying multiple causative genes at a single GWAS locus by Flister, Michael J, Tsaih, Shirng-Wern, O'Meara, Caitlin C, Endres, Bradley, Hoffman, Matthew J, Geurts, Aron M, Dwinell, Melinda R, Lazar, Jozef, Jacob, Howard J, Moreno, Carol

“…Genome-wide association studies (GWAS) are useful for nominating candidate genes, but typically are unable to establish disease causality or differentiate…”
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Hyperkalemia excursions are associated with an increased risk of mortality and hospitalizations in hemodialysis patients by Karaboyas, Angelo, Robinson, Bruce M, James, Glen, Hedman, Katarina, Moreno Quinn, Carol P, De Sequera, Patricia, Nitta, Kosaku, Pecoits-Filho, Roberto

“…Hyperkalemia is common among hemodialysis (HD) patients and has been associated with adverse clinical outcomes. Previous studies considered a single serum…”
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CD200 is a useful marker in the diagnosis of chronic lymphocytic leukemia by Mora, Alba, Bosch, Rosa, Cuellar, Carolina, Vicente, Eva Puy, Blanco, Laura, Martino, Rodrigo, Ubeda, José M., Sierra, Jorge, Moreno, Carol, Nomdedeu, Josep

“…Background The diagnosis of CLL is supported by a typical morphology and immunophenotype and usually does not present difficulties. Nevertheless, some patients…”
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PB2699: CONSENSUS FROM AN EXPERT PANEL ON THE CURRENT MANAGEMENT OF SECONDARY IMMUNODEFICIENCY IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES IN SPAIN by Boqué, Concepción, Sánchez‐Ramón, Silvia, Cordoba, Raul, Moreno, Carol, Perez, Elena Cabezudo

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Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat by Endres, Bradley T., Priestley, Jessica R. C., Palygin, Oleg, Flister, Michael J., Hoffman, Matthew J., Weinberg, Brian D., Grzybowski, Michael, Lombard, Julian H., Staruschenko, Alexander, Moreno, Carol, Jacob, Howard J., Geurts, Aron M.

“…PLEKHA7 (pleckstrin homology domain containing family A member 7) has been found in multiple studies as a candidate gene for human hypertension, yet functional…”
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FcγRIIb-BCR coligation inhibits BCR signaling in chronic lymphocytic leukemia by Bosch, Rosa, Mora, Alba, Cuellar, Carolina, Ferrer, Gerardo, Gorlatov, Sergey, Nomdedéu, Josep, Montserrat, Emili, Sierra, Jorge, Rai, Kanti R, Chiorazzi, Nicholas, Moreno, Carol

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Transposon‐mediated transgenesis, transgenic rescue, and tissue‐specific gene expression in rodents and rabbits by Katter, Katharina, Geurts, Aron M., Hoffmann, Orsolya, Mátés, Lajos, Landa, Vladimir, Hiripi, László, Moreno, Carol, Lazar, Jozef, Bashir, Sanum, Zidek, Vaclav, Popova, Elena, Jerchow, Boris, Becker, Katja, Devaraj, Anantharam, Walter, Ingrid, Grzybowksi, Michael, Corbett, Molly, Filho, Artur Rangel, Hodges, Matthew R., Bader, Michael, Ivics, Zoltán, Jacob, Howard J., Pravenec, Michal, Bősze, Zsuzsanna, Rülicke, Thomas, Izsvák, Zsuzsanna

“…Germline transgenesis is an important procedure for functional investigation of biological pathways, as well as for animal biotechnology. We have established a…”
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Progress and prospects in rat genetics: a community view by Kwitek, Anne E, Twigger, Simon N, Dominiczak, Anna, Holmdahl, Rikard, Marrone, Anna, Riley, Lela, Moreno, Carol, Cuppen, Edwin, Mullins, Linda, Worley, Kim, Serikawa, Tadao, Fernandez-Suarez, Xose M, Gauguier, Dominique, Gould, Michael, Critser, John K, Kuramoto, Takashi, Voigt, Birger, Jacob, Howard J, Flint, Jonathan, Hubner, Norbert, Mashimo, Tomoji, Shull, James D, Izsvák, Zsuzsanna, Pravenec, Michal, Szpirer, Claude, Mullins, John, Olsson, Tomas, Geurts, Aron M, Harris, Peter C, Saar, Kathrin, Aitman, Timothy J

“…The rat is an important system for modeling human disease. Four years ago, the rich 150-year history of rat research was transformed by the sequencing of the…”
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Zinc-finger nucleases: new strategies to target the rat genome by Geurts, Aron M, Moreno, Carol

“…The importance of genetic laboratory models, such as mice and rats, becomes evident when there is a poor understanding of the nature of human disease. Many rat…”
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A cross-trial comparison of single-agent ibrutinib versus chlorambucil-obinutuzumab in previously untreated patients with chronic lymphocytic leukemia or small lymphocytic lymphoma by Tedeschi, Alessandra, Greil, Richard, Demirkan, Fatih, Robak, Tadeusz, Moreno, Carol, Barr, Paul M, Anz, Bertrand, Simpson, David, Gaidano, Gianluca, Bairey, Osnat, Stevens, Don, Gill, Devinder, Flinn, Ian W, Kipps, Thomas J, Burger, Jan A, Lin, Jennifer, Webb, Thomas, Fedorov, Viktor, Styles, Lori, Gribben, John G

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Patiromer utility as an adjunct treatment in patients needing urgent hyperkalaemia management (PLATINUM): design of a multicentre, randomised, double-blind, placebo-controlled, parallel-group study by Rafique, Zubaid, Budden, Jeffrey, Quinn, Carol Moreno, Duanmu, Youyou, Safdar, Basmah, Bischof, Jason J, Driver, Brian E, Herzog, Charles A, Weir, Matthew R, Singer, Adam J, Boone, Stephen, Soto-Ruiz, Karina M, Peacock, W Frank

“…IntroductionHyperkalaemia is common, life-threatening and often requires emergency department (ED) management; however, no standardised ED treatment protocol…”
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