Search Results - "MOREIRA, I"

Oxidative Stress: A Major Player in Cerebrovascular Alterations Associated to Neurodegenerative Events by Carvalho, Cristina, Moreira, Paula I

“…The brain is one of the most exquisite organs in the body with high metabolic demands, and requires a tight regulation of the surrounding environment. This…”
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Exchange Coupling Inversion in a High-Spin Organic Triradical Molecule by Gaudenzi, R, Burzurí, E, Reta, D, Moreira, I. de P. R, Bromley, S. T, Rovira, C, Veciana, J, van der Zant, H. S. J

“…The magnetic properties of a nanoscale system are inextricably linked to its local environment. In adatoms on surfaces and inorganic layered structures, the…”
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PINK1/PARKIN signalling in neurodegeneration and neuroinflammation by Quinn, Peter M J, Moreira, Paula I, Ambrósio, António Francisco, Alves, C Henrique

“…Mutations in the PTEN-induced kinase 1 (PINK1) and Parkin RBR E3 ubiquitin-protein ligase (PARKIN) genes are associated with familial forms of Parkinson's…”
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Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology by Moreira, Paula I., Carvalho, Cristina, Zhu, Xiongwei, Smith, Mark A., Perry, George

“…Mitochondria are uniquely poised to play a pivotal role in neuronal cell survival or death because they are regulators of both energy metabolism and cell death…”
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Insulin-Induced Recurrent Hypoglycemia Up-Regulates Glucose Metabolism in the Brain Cortex of Chemically Induced Diabetic Rats by Cardoso, Susana, Moreira, Paula I

“…Diabetes is a chronic metabolic disease that seriously compromises human well-being. Various studies highlight the importance of maintaining a sufficient…”
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Temperature and dietary carbohydrate level effects on performance and metabolic utilisation of diets in European sea bass (Dicentrarchus labrax) juveniles by Moreira, I.S., Peres, H., Couto, A., Enes, P., Oliva-Teles, A.

“…This study aimed to evaluate the effect of temperature and dietary starch level on growth performance, nutrient utilisation, whole-body composition and…”
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Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins by Wang, Xinglong, Su, Bo, Siedlak, Sandra L, Moreira, Paula I, Fujioka, Hisashi, Wang, Yang, Casadesus, Gemma, Zhu, Xiongwei

“…Mitochondrial dysfunction is a prominent feature of Alzheimer disease but the underlying mechanism is unclear. In this study, we investigated the effect of…”
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Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease by Correia, Sónia C, Santos, Renato X, Santos, Maria S, Casadesus, Gemma, Lamanna, Joseph C, Perry, George, Smith, Mark A, Moreira, Paula I

“…This study aimed to show that the rat model of sporadic Alzheimer's disease (sAD) generated by the intracerebroventricular (icv) injection of a…”
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SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization by Finley, Lydia W.S., Carracedo, Arkaitz, Lee, Jaewon, Souza, Amanda, Egia, Ainara, Zhang, Jiangwen, Teruya-Feldstein, Julie, Moreira, Paula I., Cardoso, Sandra M., Clish, Clary B., Pandolfi, Pier Paolo, Haigis, Marcia C.

“…Tumor cells exhibit aberrant metabolism characterized by high glycolysis even in the presence of oxygen. This metabolic reprogramming, known as the Warburg…”
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Hormonal control of Sertoli cell metabolism regulates spermatogenesis by Alves, Marco G., Rato, Luís, Carvalho, Rui A., Moreira, Paula I., Socorro, Sílvia, Oliveira, Pedro F.

“…Hormonal regulation is essential to spermatogenesis. Sertoli cells (SCs) have functions that reach far beyond the physical support of germ cells, as they are…”
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Photodegradation of pharmaceutical persistent pollutants using hydroxyapatite-based materials by Márquez Brazón, E., Piccirillo, C., Moreira, I.S., Castro, P.M.L.

“…Pharmaceutical persistent pollutants pose a serious threat to the environment. The aim of this study was to use, for the first time, hydroxyapatite-based…”
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Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats by Candeias, Emanuel, Sebastião, Inês, Cardoso, Susana, Carvalho, Cristina, Santos, Maria Sancha, Oliveira, Catarina Resende, Moreira, Paula I., Duarte, Ana I.

“…Type 2 diabetes (T2D) is a modern socioeconomic burden, mostly due to its long-term complications affecting nearly all tissues. One of them is the brain, whose…”
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Development of ethical competences in mental health and psychiatry: simulation with nursing students by Lopes, R., Moreira, I., Neves, M., Brás, C., Rodrigues, R.

“…IntroductionSimulation as a pedagogical strategy contributes to improving the acquisition, consolidation and retention of knowledge and is very attractive for…”
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Erratum: Highly Adiabatic Time-Optimal Quantum Driving at Low Energy Cost [Phys. Rev. Lett. 129, 180402 (2022)] by Garcia, Ll, Bofill, J M, Moreira, I de P R, Albareda, G

“…This corrects the article DOI: 10.1103/PhysRevLett.129.180402…”
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Liraglutide Protects Against Brain Amyloid-β1–42 Accumulation in Female Mice with Early Alzheimer’s Disease-Like Pathology by Partially Rescuing Oxidative/Nitrosative Stress and Inflammation by Duarte, Ana I., Candeias, Emanuel, Alves, Inês N., Mena, Débora, Silva, Daniela F., Machado, Nuno J., Campos, Elisa J., Santos, Maria S., Oliveira, Catarina R., Moreira, Paula I.

“…Alzheimer’s disease (AD) is the most common form of dementia worldwide, being characterized by the deposition of senile plaques, neurofibrillary tangles…”
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Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease by Santos, Renato X, Correia, Sónia C, Zhu, Xiongwei, Smith, Mark A, Moreira, Paula I, Castellani, Rudy J, Nunomura, Akihiko, Perry, George

“…Mitochondria are fundamental to the life and proper functioning of cells. These organelles play a key role in energy production, in maintaining homeostatic…”
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The Parkinson disease pain classification system: results from an international mechanism-based classification approach by Mylius, Veit, Perez Lloret, Santiago, Cury, Rubens G., Teixeira, Manoel J., Barbosa, Victor R., Barbosa, Egberto R., Moreira, Larissa I., Listik, Clarice, Fernandes, Ana M., de Lacerda Veiga, Diogo, Barbour, Julio, Hollenstein, Nathalie, Oechsner, Matthias, Walch, Julia, Brugger, Florian, Hägele-Link, Stefan, Beer, Serafin, Rizos, Alexandra, Chaudhuri, Kallol Ray, Bouhassira, Didier, Lefaucheur, Jean-Pascal, Timmermann, Lars, Gonzenbach, Roman, Kägi, Georg, Möller, Jens Carsten, Ciampi de Andrade, Daniel

“…Pain is a common nonmotor symptom in patients with Parkinson disease (PD) but the correct diagnosis of the respective cause remains difficult because suitable…”
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Insulin signaling, glucose metabolism and mitochondria: Major players in Alzheimer's disease and diabetes interrelation by Correia, Sónia C, Santos, Renato X, Carvalho, Cristina, Cardoso, Susana, Candeias, Emanuel, Santos, Maria S, Oliveira, Catarina R, Moreira, Paula I

“…Abstract Many epidemiological studies have shown that diabetes, particularly type 2 diabetes, significantly increases the risk to develop Alzheimer's disease…”
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Cardiolipin profile changes are associated to the early synaptic mitochondrial dysfunction in Alzheimer's disease by Monteiro-Cardoso, Vera F, Oliveira, M Manuel, Melo, Tânia, Domingues, Maria R M, Moreira, Paula I, Ferreiro, Elisabete, Peixoto, Francisco, Videira, Romeu A

“…Brain mitochondria are fundamental to maintaining healthy functional brains, and their dysfunction is involved in age-related neurodegenerative disorders such…”
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Limited reproductive interference despite high rates of heterospecific pollen transfer among co‐occurring bat‐pollinated Burmeistera by Moreira‐Hernández, Juan I., Ghai, Harmeet, Terzich, Nicholas, Zambrano‐Cevallos, Ricardo, Oleas, Nora H., Muchhala, Nathan

“…Premise Many tropical plants are bat‐pollinated, but these mammals often carry copious, multispecific pollen loads making bat‐pollinated plants susceptible to…”
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