Search Results - "MOREAU, Martine"

Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis by Tran, Sophie, Baba, Ines, Poupel, Lucie, Dussaud, Sébastien, Moreau, Martine, Gélineau, Adélaïde, Marcelin, Geneviève, Magréau-Davy, Elissa, Ouhachi, Melissa, Lesnik, Philippe, Boissonnas, Alexandre, Le Goff, Wilfried, Clausen, Björn E., Yvan-Charvet, Laurent, Sennlaub, Florian, Huby, Thierry, Gautier, Emmanuel L.

“…Kupffer cells (KCs) are liver-resident macrophages that self-renew by proliferation in the adult independently from monocytes. However, how they are maintained…”
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Loss of embryonically-derived Kupffer cells during hypercholesterolemia accelerates atherosclerosis development by Fima, Rebecca, Dussaud, Sébastien, Benbida, Cheïma, Blanchet, Margault, Lanthiez, François, Poupel, Lucie, Brambilla, Claudia, Gélineau, Adélaïde, Dessena, Mattia, Blanc, Marina, Lerévérend, Cédric, Moreau, Martine, Boissonnas, Alexandre, Gautier, Emmanuel L., Huby, Thierry

“…Hypercholesterolemia is a major risk factor for atherosclerosis and associated cardiovascular diseases. The liver plays a key role in the regulation of plasma…”
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High-Density Lipoprotein Therapy in Stroke: Evaluation of Endothelial SR-BI-Dependent Neuroprotective Effects by Tran-Dinh, Alexy, Levoye, Angélique, Couret, David, Galle-Treger, Lauriane, Moreau, Martine, Delbosc, Sandrine, Hoteit, Camille, Montravers, Philippe, Amarenco, Pierre, Huby, Thierry, Meilhac, Olivier

“…High-density lipoproteins (HDLs) display endothelial protective effects. We tested the role of SR-BI, an HDL receptor expressed by endothelial cells, in the…”
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Role of Scavenger Receptor Class B Type I in Hepatitis C Virus Entry: Kinetics and Molecular Determinants by CATANESE, Maria Teresa, ANSUINI, Helenia, NICOSIA, Alfredo, GRAZIANI, Rita, HUBY, Thierry, MOREAU, Martine, BALL, Jonathan K, PAONESSA, Giacomo, RICE, Charles M, CORTESE, Riccardo, VITELLI, Alessandra

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High-Avidity Monoclonal Antibodies against the Human Scavenger Class B Type I Receptor Efficiently Block Hepatitis C Virus Infection in the Presence of High-Density Lipoprotein by CATANESE, Maria Teresa, GRAZIANI, Rita, VITELLI, Alessandra, NICOSIA, Alfredo, VON HAHN, Thomas, MOREAU, Martine, HUBY, Thierry, PAONESSA, Giacomo, SANTINI, Claudia, LUZZAGO, Alessandra, RICE, Charles M, CORTESE, Riccardo

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Adrenocortical scavenger receptor class B type I deficiency exacerbates endotoxic shock and precipitates sepsis-induced mortality in mice by Gilibert, Sophie, Galle-Treger, Lauriane, Moreau, Martine, Saint-Charles, Flora, Costa, Sara, Ballaire, Raphaëlle, Couvert, Philippe, Carrié, Alain, Lesnik, Philippe, Huby, Thierry

“…Scavenger receptor class B type I (SR-BI)-deficient mice display reduced survival to endotoxic shock and sepsis. The understanding of the mechanisms underlying…”
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Scavenger Receptor BI and BII Expression Levels Modulate Hepatitis C Virus Infectivity by GROVE, Joe, HUBY, Thierry, BAIFE, Peter, MCKEATING, Jane A, STAMATAKI, Zania, VANWOLLEGHEM, Thomas, MEULEMAN, Philip, FARQUHAR, Michelle, SCHWARZ, Anne, MOREAU, Martine, OWEN, James S, LEROUX-ROELS, Geert

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Cholesteryl Ester Transfer Protein Expression Partially Attenuates the Adverse Effects of SR-BI Receptor Deficiency on Cholesterol Metabolism and Atherosclerosis by El Bouhassani, Majda, Gilibert, Sophie, Moreau, Martine, Saint-Charles, Flora, Tréguier, Morgan, Poti, Francesco, Chapman, M. John, Le Goff, Wilfried, Lesnik, Philippe, Huby, Thierry

“…Scavenger receptor SR-BI significantly contributes to HDL cholesterol metabolism and atherogenesis in mice. However, the role of SR-BI may not be as pronounced…”
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Scavenger receptor BI boosts hepatocyte permissiveness to Plasmodium infection by Yalaoui, Samir, Huby, Thierry, Franetich, Jean-François, Gego, Audrey, Rametti, Armelle, Moreau, Martine, Collet, Xavier, Siau, Anthony, van Gemert, Geert-Jan, Sauerwein, Robert W, Luty, Adrian J F, Vaillant, Jean-Christophe, Hannoun, Laurent, Chapman, John, Mazier, Dominique, Froissard, Patrick

“…Infection of hepatocytes by Plasmodium falciparum sporozoites requires the host tetraspanin CD81. CD81 is also predicted to be a coreceptor, along with…”
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Rosuvastatin reduces MMP-7 secretion by human monocyte-derived macrophages: potential relevance to atherosclerotic plaque stability by Furman, Christophe, Copin, Corinne, Kandoussi, Mejid, Davidson, Robert, Moreau, Martine, McTaggiart, Fergus, Chapman, M.John, Fruchart, Jean-Charles, Rouis, Mustapha

“…3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) have been shown to reduce cardiovascular morbidity and mortality by their…”
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Transcription Factor Sterol Regulatory Element Binding Protein 2 Regulates Scavenger Receptor Cla-1 Gene Expression by Tréguier, Morgan, Doucet, Chantal, Moreau, Martine, Dachet, Christiane, Thillet, Joëlle, Chapman, M John, Huby, Thierry

“…OBJECTIVE—The human scavenger receptor class B type I (Cla-1) plays a key role in cellular cholesterol movement in facilitating transport of cholesterol…”
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Targeted invalidation of SR-B1 in macrophages reduces macrophage apoptosis and accelerates atherosclerosis by Galle-Treger, Lauriane, Moreau, Martine, Ballaire, Raphaëlle, Poupel, Lucie, Huby, Thomas, Sasso, Emanuele, Troise, Fulvia, Poti, Francesco, Lesnik, Philippe, Le Goff, Wilfried, Gautier, Emmanuel L, Huby, Thierry

“…Abstract Aims SR-B1 is a cholesterol transporter that exerts anti-atherogenic properties in liver and peripheral tissues in mice. Bone marrow (BM) transfer…”
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Targeted invalidation of SR-B1 in macrophages reduces macrophage apoptosis and accelerates atherosclerosis by Galle-Treger, Lauriane, Moreau, Martine, Ballaire, Raphaëlle, Poupel, Lucie, Huby, Thomas, Sasso, Emanuele, Troise, Fulvia, Poti, Francesco, Lesnik, Philippe, Le Goff, Wilfried, Gautier, Emmanuel, Huby, Thierry

“…Abstract Aims SR-B1 is a cholesterol transporter that exerts anti-atherogenic properties in liver and peripheral tissues in mice. Bone marrow (BM) transfer…”
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interaction of natural hepatitis C virus with human scavenger receptor SR-BI/Cla1 is mediated by ApoB-containing lipoproteins by Maillard, Patrick, Huby, Thierry, Andréo, Ursula, Moreau, Martine, Chapman, John, Budkowska, Agata

“…ABSTRACT The possible role of candidate receptors in the cellular penetration of HCV from serum of infected patients remains unclear. SR‐BI/Cla1 interacts with…”
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The Promoter of Human Tissue Factor Pathway Inhibitor Gene by Petit, Laure, Lesnik, Philippe, Dachet, Christiane, Hugou, Isabelle, Moreau, Martine, Chapman, John, Rouis, Mustapha

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LDL particle subspecies are distinct in their capacity to mediate free cholesterol efflux via the SR-BI/Cla-1 receptor by Tréguier, Morgan, Moreau, Martine, Sposito, Andrei, Chapman, M. John, Huby, Thierry

“…The human scavenger receptor SR-BI/Cla-1 promotes efflux of free cholesterol from cells to both high-density and low-density lipoproteins (HDL, LDL)…”
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Interleukin-8 mediates downregulation of tissue inhibitor of metalloproteinase-1 expression in cholesterol-loaded human macrophages : Relevance to stability of atherosclerotic plaque by MOREAU, M, BROCHERIOU, I, PETIT, L, NINIO, E, CHAPMAN, M. J, ROUIS, M

“…The accumulation of macrophage-derived foam cells in atherosclerotic lesions correlates with increased local release of matrix-degrading metalloproteinases…”
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Differential regulation of the human versus the mouse apolipoprotein AV gene by PPARalpha. Implications for the study of pharmaceutical modifiers of hypertriglyceridemia in mice by Prieur, Xavier, Lesnik, Philippe, Moreau, Martine, Rodríguez, Joan C, Doucet, Chantal, Chapman, M John, Huby, Thierry

“…Mice have been used widely to define the mechanism of action of fibric acid derivatives. The fibrates are pharmacological agonists of the peroxisome…”
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Differential regulation of the human versus the mouse apolipoprotein AV gene by PPARalpha by Prieur, Xavier, Lesnik, Philippe, Moreau, Martine, Rodríguez, Joan C., Doucet, Chantal, Chapman, M. John, Huby, Thierry

“…Mice have been used widely to define the mechanism of action of fibric acid derivatives. The fibrates are pharmacological agonists of the peroxisome…”
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Tissue Factor Pathway Inhibitor Is Expressed by Human Monocyte-Derived Macrophages: Relationship to Tissue Factor Induction by Cholesterol and Oxidized LDL by Petit, Laure, Lesnik, Philippe, Dachet, Christiane, Moreau, Martine, Chapman, M. John

“…Lipid-laden macrophages express tissue factor (TF), which may activate the extrinsic coagulation pathway on rupture of the atherosclerotic plaque. Tissue…”
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