Search Results - "MORARI, Joseane"

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    Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity by Cintra, Dennys E, Ropelle, Eduardo R, Moraes, Juliana C, Pauli, José R, Morari, Joseane, Souza, Claudio T de, Grimaldi, Renato, Stahl, Marcela, Carvalheira, José B, Saad, Mario J, Velloso, Licio A

    Published in PloS one (18-01-2012)
    “…In experimental models, hypothalamic inflammation is an early and determining factor in the installation and progression of obesity. Pharmacological and…”
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    An older diabetes-induced mice model for studying skin wound healing by Poblete Jara, Carlos, Nogueira, Guilherme, Morari, Joseane, do Prado, Thaís Paulino, de Medeiros Bezerra, Renan, Velloso, Lício A, Velander, William, de Araújo, Eliana Pereira

    Published in PloS one (17-02-2023)
    “…Advances in wound treatment depend on the availability of animal models that reflect key aspects of human wound healing physiology. To this date, the accepted…”
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    Interleukin-6 actions in the hypothalamus protects against obesity and is involved in the regulation of neurogenesis by Bobbo, Vanessa C, Engel, Daiane F, Jara, Carlos Poblete, Mendes, Natalia F, Haddad-Tovolli, Roberta, Prado, Thais P, Sidarta-Oliveira, Davi, Morari, Joseane, Velloso, Licio A, Araujo, Eliana P

    Published in Journal of neuroinflammation (31-08-2021)
    “…Interleukin-6 (IL6) produced in the context of exercise acts in the hypothalamus reducing obesity-associated inflammation and restoring the control of food…”
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    High-Fat Diet Induces Apoptosis of Hypothalamic Neurons by Moraes, Juliana C, Coope, Andressa, Morari, Joseane, Cintra, Dennys E, Roman, Erika A, Pauli, Jose R, Romanatto, Talita, Carvalheira, Jose B, Oliveira, Alexandre L.R, Saad, Mario J, Velloso, Licio A

    Published in PloS one (02-04-2009)
    “…Consumption of dietary fats is amongst the most important environmental factors leading to obesity. In rodents, the consumption of fat-rich diets blunts leptin…”
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    Endoplasmic Reticulum Stress in Colonic Mucosa of Ulcerative Colitis Patients Is Mediated by PERK and IRE1 Pathway Activation by Rodrigues, Bruno Lima, Dotti, Isabella, Pascoal, Lívia Bitencourt, Morari, Joseane, Esteller, Miriam, Coope, Andressa, Ayrizono, Maria de Lourdes Setsuko, Salas, Azucena, Leal, Raquel Franco

    Published in Mediators of inflammation (09-02-2022)
    “…Ulcerative colitis (UC) is characterized by a chronic overproduction of proinflammatory cytokines. During an acute phase, the endoplasmic reticulum (ER) is…”
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    Interleukin-6 Expression by Hypothalamic Microglia in Multiple Inflammatory Contexts: A Systematic Review by Velloso, Lício A., Morari, Joseane, Mendes, Natália F., Jara, Carlos P., Bobbo, Vanessa C. D., Araújo, Eliana P.

    Published in BioMed research international (2019)
    “…Interleukin-6 (IL-6) is a unique cytokine that can play both pro- and anti-inflammatory roles depending on the anatomical site and conditions under which it…”
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    Pregnancy Protects against Abnormal Gut Permeability Promoted via the Consumption of a High-Fat Diet in Mice by Biolcatti, Caio F, Bobbo, Vanessa C, Solon, Carina, Morari, Joseane, Haddad-Tovolli, Roberta, Araujo, Eliana P, Simoes, Marcela R, Velloso, Licio A

    Published in Nutrients (01-12-2023)
    “…The consumption of large amounts of dietary fats and pregnancy are independent factors that can promote changes in gut permeability and the gut microbiome…”
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    Dietary fats promote functional and structural changes in the median eminence blood/spinal fluid interface-the protective role for BDNF by Ramalho, Albina F, Bombassaro, Bruna, Dragano, Nathalia R, Solon, Carina, Morari, Joseane, Fioravante, Milena, Barbizan, Roberta, Velloso, Licio A, Araujo, Eliana P

    Published in Journal of neuroinflammation (09-01-2018)
    “…The consumption of large amounts of dietary fats activates an inflammatory response in the hypothalamus, damaging key neurons involved in the regulation of…”
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    Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity by Souza, Gabriela F. P., Solon, Carina, Nascimento, Lucas F., De-Lima-Junior, Jose C., Nogueira, Guilherme, Moura, Rodrigo, Rocha, Guilherme Z., Fioravante, Milena, Bobbo, Vanessa, Morari, Joseane, Razolli, Daniela, Araujo, Eliana P., Velloso, Licio A.

    Published in Scientific reports (04-07-2016)
    “…Obesity is the result of a long-term positive energy balance in which caloric intake overrides energy expenditure. This anabolic state results from the…”
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    n-3 Fatty Acids Induce Neurogenesis of Predominantly POMC-Expressing Cells in the Hypothalamus by Nascimento, Lucas F R, Souza, Gabriela F P, Morari, Joseane, Barbosa, Guilherme O, Solon, Carina, Moura, Rodrigo F, Victório, Sheila C, Ignácio-Souza, Letícia M, Razolli, Daniela S, Carvalho, Hernandes F, Velloso, Lício A

    Published in Diabetes (New York, N.Y.) (01-03-2016)
    “…Apoptosis of hypothalamic neurons is believed to play an important role in the development and perpetuation of obesity. Similar to the hippocampus, the…”
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    Protein C Pretreatment Protects Endothelial Cells from SARS-CoV-2-Induced Activation by Silva, Bruna Rafaela Dos Santos, Sidarta-Oliveira, Davi, Morari, Joseane, Bombassaro, Bruna, Jara, Carlos Poblete, Simeoni, Camila Lopes, Parise, Pierina Lorencini, Proenca-Modena, José Luiz, Velloso, Licio A, Velander, William H, Araújo, Eliana P

    Published in Viruses (01-07-2024)
    “…SARS-CoV-2 can induce vascular dysfunction and thrombotic events in patients with severe COVID-19; however, the cellular and molecular mechanisms behind these…”
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    TLR4 Expression in Bone Marrow-Derived Cells Is Both Necessary and Sufficient to Produce the Insulin Resistance Phenotype in Diet-Induced Obesity by Razolli, Daniela S, Moraes, Juliana C, Morari, Joseane, Moura, Rodrigo F, Vinolo, Marco A, Velloso, Licio A

    Published in Endocrinology (Philadelphia) (01-01-2015)
    “…The anomalous activation of toll-like receptor 4 (TLR4) by dietary fats is one of the most important mechanisms linking obesity to insulin resistance. TLR4 is…”
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    Novel Role of CETP in Macrophages: Reduction of Mitochondrial Oxidants Production and Modulation of Cell Immune-Metabolic Profile by Dorighello, Gabriel G, Assis, Leandro H. P, Rentz, Thiago, Morari, Joseane, Santana, Monique F. M, Passarelli, Marisa, Ridgway, Neale D, Vercesi, Anibal E, Oliveira, Helena C. F

    Published in Antioxidants (31-08-2022)
    “…Plasma cholesteryl ester transfer protein (CETP) activity diminishes HDL-cholesterol levels and thus may increase atherosclerosis risk. Experimental evidence…”
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    Interleukin-10 is a protective factor against diet-induced insulin resistance in liver by Cintra, Dennys E, Pauli, José R, Araújo, Eliana P, Moraes, Juliana C, de Souza, Cláudio T, Milanski, Marciane, Morari, Joseane, Gambero, Alessandra, Saad, Mário J, Velloso, Licio A

    Published in Journal of hepatology (01-04-2008)
    “…Background/Aims The anti-inflammatory cytokine, interleukin-10 (IL-10), is known to exert a protective role in hepatic damage caused by viruses, alcohol,…”
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