Search Results - "MORALES, Pablo"
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Unprecedented diterpene skeletons isolated from vascular plants in the last twenty years (2001–2021)
Published in Phytochemistry (Oxford) (01-12-2022)“…Every year there are hundreds of reports about the isolation of undescribed terpenoids based on novel functionalizations of known carbocyclic skeletons series…”
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2
Is Mitochondrial Dysfunction a Common Root of Noncommunicable Chronic Diseases?
Published in Endocrine reviews (01-06-2020)“…Abstract Mitochondrial damage is implicated as a major contributing factor for a number of noncommunicable chronic diseases such as cardiovascular diseases,…”
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3
A High Dynamic Range Protein Sensing Platform for Low-volume Magneto Immunoassay Automation
Published in IEEE sensors journal (15-06-2023)“…Immunoassays have been employed in diagnosing numerous diseases. Typically, these tests require a large volume of biofluid sample and overnight reaction. In…”
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4
Emerging role of mitophagy in cardiovascular physiology and pathology
Published in Molecular aspects of medicine (01-02-2020)“…Healthy mitochondrial function is imperative for most tissues, but especially those with a high energy demand. Robust evidence linking mitochondrial…”
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Estimating the environmental impacts of a brewery waste–based biorefinery: Bio-ethanol and xylooligosaccharides joint production case study
Published in Industrial crops and products (01-11-2018)“…•Large scale design was performed for valorization of barley straw and BSG.•The valorization sequence is based on the joint production of bio-ethanol and…”
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6
Thermodynamics of exponential Kolmogorov–Nagumo averages
Published in New journal of physics (01-07-2023)“…Abstract This paper investigates generalized thermodynamic relationships in physical systems where relevant macroscopic variables are determined by the…”
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7
Muscle Lipid Metabolism: Role of Lipid Droplets and Perilipins
Published in Journal of diabetes research (01-01-2017)“…Skeletal muscle is one of the main regulators of carbohydrate and lipid metabolism in our organism, and therefore, it is highly susceptible to changes in…”
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Engineering the Absorption and Field Enhancement Properties of Au–TiO2 Nanohybrids via Whispering Gallery Mode Resonances for Photocatalytic Water Splitting
Published in ACS nano (26-04-2016)“…Recently, surface plasmon resonance (SPR) effects have been widely used to construct photocatalysts which are active in the visible spectral region. Such…”
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Sarcoplasmic reticulum–mitochondria communication in cardiovascular pathophysiology
Published in Nature reviews cardiology (01-06-2017)“…Key Points Sarco/endoplasmic reticulum–mitochondria communication and mitochondrial dynamics are essential regulators of mitochondrial function, cellular…”
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Socio-hydrological resilience of an arid aquifer system, subject to changing climate and inadequate agricultural management: A case study from the Valley of Santo Domingo, Mexico
Published in Journal of hydrology (Amsterdam) (01-04-2018)“…•Groundwater overexploitation due to excessive water extraction for agricultural irrigation.•Characterization of the hydrological resilience of a water-limited…”
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11
Autophagy mediates tumor necrosis factor-α-induced phenotype switching in vascular smooth muscle A7r5 cell line
Published in PloS one (11-05-2018)“…Vascular smooth muscle cells (VSMC) dedifferentiation from a contractile to a synthetic phenotype contributes to atherosclerosis. Atherosclerotic tissue has a…”
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Improving Single Injection CSF Delivery of AAV9-mediated Gene Therapy for SMA: A Dose–response Study in Mice and Nonhuman Primates
Published in Molecular therapy (01-03-2015)“…Spinal muscular atrophy (SMA) is the most frequent lethal genetic neurodegenerative disorder in infants. The disease is caused by low abundance of the survival…”
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13
Production of Oligosaccharides from Agrofood Wastes
Published in Fermentation (Basel) (01-03-2020)“…The development of biorefinery processes to platform chemicals for most lignocellulosic substrates, results in side processes to intermediates such as…”
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14
The neurocognitive impact of loneliness and social networks on social adaptation
Published in Scientific reports (25-07-2023)“…Social adaptation arises from the interaction between the individual and the social environment. However, little empirical evidence exists regarding the…”
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The Causal Effect of Testosterone on Men's Competitive Behavior Is Moderated by Basal Cortisol and Cues to an Opponent's Status: Evidence for a Context-Dependent Dual-Hormone Hypothesis
Published in Journal of personality and social psychology (01-10-2022)“…Testosterone has been theorized to direct status-seeking behaviors, including competitive behavior. However, most human studies to date have adopted…”
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Impacts of Climate Change in the El Vizcaino Biosphere Reserve (REBIVI): Challenges for Coastal Communities and the Conservation of Biodiversity
Published in Diversity (Basel) (01-09-2022)“…The impacts of climate change put pressure onto environmental and natural resources, which in turn increases the vulnerability of ecosystems and human…”
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Insulin and IGF-1 receptors regulate complex I-dependent mitochondrial bioenergetics and supercomplexes via FoxOs in muscle
Published in The Journal of clinical investigation (15-09-2021)“…Decreased skeletal muscle strength and mitochondrial dysfunction are characteristic of diabetes. The actions of insulin and IGF-1 through the insulin receptor…”
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18
Microalgae Synthesize Hydrocarbons from Long-Chain Fatty Acids via a Light-Dependent Pathway
Published in Plant physiology (Bethesda) (01-08-2016)“…Microalgae are considered a promising platform for the production of lipid-based biofuels. While oil accumulation pathways are intensively researched, the…”
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Learning from crowds in digital pathology using scalable variational Gaussian processes
Published in Scientific reports (02-06-2021)“…The volume of labeled data is often the primary determinant of success in developing machine learning algorithms. This has increased interest in methods for…”
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Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN
Published in Nature biotechnology (01-03-2010)“…Spinal muscular atrophy (SMA), the most common autosomal recessive neurodegenerative disease affecting children, results in impaired motor neuron function…”
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