Search Results - "MORALES, Olivier"
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Could Photodynamic Therapy Be a Promising Therapeutic Modality in Hepatocellular Carcinoma Patients? A Critical Review of Experimental and Clinical Studies
Published in Cancers (15-10-2021)“…Photodynamic Therapy (PDT) relies on local or systemic administration of a light-sensitive dye, called photosensitizer, to accumulate into the target site…”
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Control of the Inflammatory Response Mechanisms Mediated by Natural and Induced Regulatory T-Cells in HCV-, HTLV-1-, and EBV-Associated Cancers
Published in Mediators of Inflammation (01-01-2014)“…Virus infections are involved in chronic inflammation and, in some cases, cancer development. Although a viral infection activates the immune system’s response…”
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IL-23/IL-17A axis correlates with the nitric oxide pathway in inflammatory bowel disease: immunomodulatory effect of retinoic acid
Published in Journal of interferon & cytokine research (01-07-2013)“…Inflammatory bowel diseases (IBDs) are chronic inflammatory diseases of the gastrointestinal tract, which are clinically present as 1 of the 2 disorders,…”
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Photodynamic Therapy Using a Rose-Bengal Photosensitizer for Hepatocellular Carcinoma Treatment: Proposition for a Novel Green LED-Based Device for In Vitro Investigation
Published in Biomedicines (18-09-2024)“…Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Despite new treatments, the HCC rate remains important, making it necessary to…”
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Sperm kinematic subpopulations of the American crocodile (Crocodylus acutus)
Published in PloS one (09-03-2021)“…There has been very limited use of computer assisted semen analysis (CASA) to evaluate reptile sperm. The aim of this study was to examine sperm kinematic…”
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Inhibition of Latent Membrane Protein 1 Impairs the Growth and Tumorigenesis of Latency II Epstein-Barr Virus-Transformed T Cells
Published in Journal of Virology (01-04-2012)“…Epstein-Barr virus (EBV) is a common human herpesvirus. Infection with EBV is associated with several human malignancies in which the virus expresses a set of…”
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CD49b, a Major Marker of Regulatory T-Cells Type 1, Predicts the Response to Antiviral Therapy of Recurrent Hepatitis C after Liver Transplantation
Published in BioMed research international (01-01-2014)“…The TRANSPEG study was a prospective study to assess the efficacy of antiviral therapy in patients with a recurrent hepatitis C virus (HCV) after liver…”
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Novel Therapies Boosting T Cell Immunity in Epstein Barr Virus-Associated Nasopharyngeal Carcinoma
Published in International journal of molecular sciences (16-06-2020)“…Nasopharyngeal carcinoma (NPC) is a malignant tumour of the head and neck affecting localised regions of the world, with the highest rates described in…”
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All-Trans Retinoic Acid Modulates TLR4/NF-κB Signaling Pathway Targeting TNF-α and Nitric Oxide Synthase 2 Expression in Colonic Mucosa during Ulcerative Colitis and Colitis Associated Cancer
Published in Mediators of inflammation (01-01-2017)“…Colitis associated cancer (CAC) is the colorectal cancer (CRC) subtype that is associated with bowel disease such as ulcerative colitis (UC). The data on role…”
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Effect of nasopharyngeal carcinoma-derived exosomes on human regulatory T cells
Published in JNCI : Journal of the National Cancer Institute (01-01-2015)“…Regulatory T cells (Treg) and tumor-exosomes are thought to play a role in preventing the rejection of malignant cells in patients bearing nasopharyngeal…”
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An Efficient 5-Aminolevulinic Acid Photodynamic Therapy Treatment for Human Hepatocellular Carcinoma
Published in International journal of molecular sciences (21-06-2023)“…Photodynamic therapy (PDT) is a two-stage treatment relying on cytotoxicity induced by photoexcitation of a nontoxic dye, called photosensitizer (PS). Using…”
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Folate Receptor Targeted Photodynamic Therapy: A Novel Way to Stimulate Anti-Tumor Immune Response in Intraperitoneal Ovarian Cancer
Published in International journal of molecular sciences (01-07-2023)“…Photodynamic therapy (PDT) has shown improvements in cancer treatment and in the induction of a proper anti-tumor immune response. However, current…”
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Combination of High Dose Hypofractionated Radiotherapy with Anti-PD1 Single Dose Immunotherapy Leads to a Th1 Immune Activation Resulting in a Complete Clinical Response in a Melanoma Patient
Published in International journal of molecular sciences (15-09-2020)“…The development of immunotherapy has recently modified the anti-tumor therapeutic arsenal; particularly, immune checkpoint inhibitors have led to a significant…”
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Targeted Photodynamic Therapy using a Vectorized Photosensitizer coupled to Folic Acid Analog induces Ovarian Tumor Cell Death and inhibits IL-6-mediated Inflammation
Published in Journal of controlled release (01-07-2024)“…Ovarian cancer (OC) is one of the most lethal cancers among women. Frequent recurrence in the peritoneum due to the presence of microscopic tumor residues…”
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A novel anti-galectin-9 immunotherapy limits the early progression of pancreatic neoplastic lesions in transgenic mice
Published in Frontiers in immunology (2023)“…Pancreatic adenocarcinoma (PDAC) is a devastating disease with an urgent need for therapeutic innovation. Immune checkpoint inhibition has shown promise in a…”
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Characterization of neutralizing antibodies reacting with the 213-224 amino-acid segment of human galectin-9
Published in PloS one (11-09-2018)“…Extra-cellular galectin-9 (gal-9) is an immuno-modulatory protein with predominant immunosuppressive effects. Inappropriate production of gal-9 has been…”
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Effect of a vitamin supplement and three species of food plants (Fabaceae) on the production of Morpho helenor butterflies (Nymphalidae:Lepidoptera)
Published in Cuadernos de investigación UNED (28-09-2017)“…Little has been published on the use of artificial diets for the production of butterflies in the Nymphalidae family. We evaluated the effect of a commercial…”
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Epstein–Barr virus infection induces an increase of T regulatory type 1 cells in Hodgkin lymphoma patients
Published in British journal of haematology (01-09-2014)“…Summary Epstein–Barr Virus (EBV) is present in the neoplastic cells of around 20–30% of patients with Hodgkin Lymphoma (HL). Although, an immunosuppressive…”
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An Efficient Photodynamic Therapy Treatment for Human Pancreatic Adenocarcinoma
Published in Journal of clinical medicine (10-01-2020)“…To date, pancreatic adenocarcinoma (ADKP) is a devastating disease for which the incidence rate is close to the mortality rate. The survival rate has evolved…”
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Extracellular vesicles derived from nasopharyngeal carcinoma induce the emergence of mature regulatory dendritic cells using a galectin‐9 dependent mechanism
Published in Journal of extracellular vesicles (01-12-2023)“…Nasopharyngeal carcinoma‐derived small extracellular vesicles (NPCSEVs) have an immunosuppressive impact on the tumour microenvironment. In this study, we…”
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