Search Results - "MORAES, Theo J"

Composition and Variation of the Human Milk Microbiota Are Influenced by Maternal and Early-Life Factors by Moossavi, Shirin, Sepehri, Shadi, Robertson, Bianca, Bode, Lars, Goruk, Sue, Field, Catherine J., Lix, Lisa M., de Souza, Russell J., Becker, Allan B., Mandhane, Piushkumar J., Turvey, Stuart E., Subbarao, Padmaja, Moraes, Theo J., Lefebvre, Diana L., Sears, Malcolm R., Khafipour, Ehsan, Azad, Meghan B.

“…Breastmilk contains a complex community of bacteria that may help seed the infant gut microbiota. The composition and determinants of milk microbiota are…”
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Identification of nucleolin as a cellular receptor for human respiratory syncytial virus by Tayyari, Farnoosh, Marchant, David, Moraes, Theo J, Duan, Wenming, Mastrangelo, Peter, Hegele, Richard G

“…Respiratory syncytial virus (RSV) is a common airway pathogen that can cause severe illness, yet there is no vaccine or effective therapy available. Tayyari et…”
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Prevention and Treatment Strategies for Respiratory Syncytial Virus (RSV) by Gatt, Dvir, Martin, Isaac, AlFouzan, Rawan, Moraes, Theo J

“…Respiratory syncytial virus (RSV) is a leading cause of severe lower respiratory tract disease, especially in young children. Despite its global impact on…”
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Screen-time is associated with inattention problems in preschoolers: Results from the CHILD birth cohort study by Tamana, Sukhpreet K, Ezeugwu, Victor, Chikuma, Joyce, Lefebvre, Diana L, Azad, Meghan B, Moraes, Theo J, Subbarao, Padmaja, Becker, Allan B, Turvey, Stuart E, Sears, Malcolm R, Dick, Bruce D, Carson, Valerie, Rasmussen, Carmen, Pei, Jacqueline, Mandhane, Piush J

“…Pre-school children spend an average of two-hours daily using screens. We examined associations between screen-time on pre-school behavior using data from the…”
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IGF1R is an entry receptor for respiratory syncytial virus by Griffiths, Cameron D., Bilawchuk, Leanne M., McDonough, John E., Jamieson, Kyla C., Elawar, Farah, Cen, Yuchen, Duan, Wenming, Lin, Cindy, Song, Haeun, Casanova, Jean-Laurent, Ogg, Steven, Jensen, Lionel Dylan, Thienpont, Bernard, Kumar, Anil, Hobman, Tom C., Proud, David, Moraes, Theo J., Marchant, David J.

“…Pneumonia resulting from infection is one of the leading causes of death worldwide. Pulmonary infection by the respiratory syncytial virus (RSV) is a large…”
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Delayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease by Hoskinson, Courtney, Dai, Darlene L. Y., Del Bel, Kate L., Becker, Allan B., Moraes, Theo J., Mandhane, Piushkumar J., Finlay, B. Brett, Simons, Elinor, Kozyrskyj, Anita L., Azad, Meghan B., Subbarao, Padmaja, Petersen, Charisse, Turvey, Stuart E.

“…Allergic diseases affect millions of people worldwide. An increase in their prevalence has been associated with alterations in the gut microbiome, i.e., the…”
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An overview of systematic reviews on predictors of smoking cessation among young people by Kundu, Anasua, Sultana, Nahid, Felsky, Daniel, Moraes, Theo J, Selby, Peter, Chaiton, Michael

“…Understanding the factors that influence smoking cessation among young people is crucial for planning targeted cessation approaches. The objective of this…”
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Decreasing antibiotic use, the gut microbiota, and asthma incidence in children: evidence from population-based and prospective cohort studies by Patrick, David M, Sbihi, Hind, Dai, Darlene L Y, Al Mamun, Abdullah, Rasali, Drona, Rose, Caren, Marra, Fawziah, Boutin, Rozlyn C T, Petersen, Charisse, Stiemsma, Leah T, Winsor, Geoffrey L, Brinkman, Fiona S L, Kozyrskyj, Anita L, Azad, Meghan B, Becker, Allan B, Mandhane, Piush J, Moraes, Theo J, Sears, Malcolm R, Subbarao, Padmaja, Finlay, B Brett, Turvey, Stuart E

“…Childhood asthma incidence is decreasing in some parts of Europe and North America. Antibiotic use in infancy has been associated with increased asthma risk…”
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ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel by Wu, Yu-Sheng, Jiang, Janet, Ahmadi, Saumel, Lew, Alexandria, Laselva, Onofrio, Xia, Sunny, Bartlett, Claire, Ip, Wan, Wellhauser, Leigh, Ouyang, Hong, Gonska, Tanja, Moraes, Theo J, Bear, Christine E

“…ORKAMBI, a combination of the corrector, lumacaftor, and the potentiator, ivacaftor, partially rescues the defective processing and anion channel activity…”
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A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity by Marchant, David J, Bellac, Caroline L, Moraes, Theo J, Wadsworth, Samuel J, Dufour, Antoine, Butler, Georgina S, Bilawchuk, Leanne M, Hendry, Reid G, Robertson, A Gordon, Cheung, Caroline T, Ng, Julie, Ang, Lisa, Luo, Zongshu, Heilbron, Karl, Norris, Michael J, Duan, Wenming, Bucyk, Taylor, Karpov, Andrei, Devel, Laurent, Georgiadis, Dimitris, Hegele, Richard G, Luo, Honglin, Granville, David J, Dive, Vincent, McManus, Bruce M, Overall, Christopher M

“…Matrix metalloproteinases (MMPs) normally act extracellularly. Now Marchant et al . report an unexpected nuclear activity for MMP-12 in virus-infected cells in…”
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Prediction of odds for emergency cesarean section: A secondary analysis of the CHILD term birth cohort study by Tun, Mon H, Chari, Radha, Kaul, Padma, Mamede, Fabiana V, Paulden, Mike, Lefebvre, Diana L, Turvey, Stuart E, Moraes, Theo J, Sears, Malcolm R, Subbarao, Padmaja, Mandhane, Piush J

“…Introduction Previously developed cesarean section (CS) and emergency CS prediction tools use antenatal and intrapartum risk factors. We aimed to develop a…”
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Bacteroides-dominant gut microbiome of late infancy is associated with enhanced neurodevelopment by Tamana, Sukhpreet K., Tun, Hein M., Konya, Theodore, Chari, Radha S., Field, Catherine J., Guttman, David S., Becker, Allan B., Moraes, Theo J., Turvey, Stuart E., Subbarao, Padmaja, Sears, Malcolm R., Pei, Jacqueline, Scott, James A., Mandhane, Piush J., Kozyrskyj, Anita L.

“…Dysbiosis of gut microbiota has been retrospectively linked to autism spectrum disorders but the temporal association between gut microbiota and early…”
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M1-like, but not M0- or M2-like, macrophages, reduce RSV infection of primary bronchial epithelial cells in a media-dependent fashion by Ronaghan, Natalie J, Soo, Mandy, Pena, Uriel, Tellis, Marisa, Duan, Wenming, Tabatabaei-Zavareh, Nooshin, Kramer, Philipp, Hou, Juan, Moraes, Theo J

“…Respiratory syncytial virus (RSV) is a common childhood infection that in young infants can progress into severe bronchiolitis and pneumonia. Disease…”
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Correction to: Examining psychosocial pathways to explain the link between breastfeeding practices and child behaviour in a longitudinal cohort by Turner, Sarah E, Roos, Leslie, Nickel, Nathan, Pei, Jacqueline, Mandhane, Piushkumar J, Moraes, Theo J, Turvey, Stuart E, Simons, Elinor, Subbarao, Padmaja, Azad, Meghan B

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Natural environments in the urban context and gut microbiota in infants by Nielsen, Charlene C., Gascon, Mireia, Osornio-Vargas, Alvaro R., Shier, Catherine, Guttman, David S., Becker, Allan B., Azad, Meghan B., Sears, Malcolm R., Lefebvre, Diana L., Moraes, Theo J., Turvey, Stuart E., Subbarao, Padmaja, Takaro, Tim K., Brook, Jeffrey R., Scott, James A., Mandhane, Piush J., Tun, Hein M., Kozyrskyj, Anita L.

“…•Proximity to natural urban environments – their vegetation, soil or water – may be beneficial for early life microbiota.•Tested influence of a natural…”
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Examining psychosocial pathways to explain the link between breastfeeding practices and child behaviour in a longitudinal cohort by Turner, Sarah E, Roos, Leslie, Nickel, Nathan, Pei, Jacqueline, Mandhane, Piushkumar J, Moraes, Theo J, Turvey, Stuart E, Simons, Elinor, Subbarao, Padmaja, Azad, Meghan B

“…Breastfeeding is associated with reduced postpartum depression, stronger parent-child relationships, and fewer behavioral disorders in early childhood. We…”
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Influenza infects lung microvascular endothelium leading to microvascular leak: role of apoptosis and claudin-5 by Armstrong, Susan M, Wang, Changsen, Tigdi, Jayesh, Si, Xiaoe, Dumpit, Carlo, Charles, Steffany, Gamage, Asela, Moraes, Theo J, Lee, Warren L

“…Severe influenza infections are complicated by acute lung injury, a syndrome of pulmonary microvascular leak. The pathogenesis of this complication is unclear…”
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Early human fetal lung atlas reveals the temporal dynamics of epithelial cell plasticity by Quach, Henry, Farrell, Spencer, Wu, Ming Jia Michael, Kanagarajah, Kayshani, Leung, Joseph Wai-Hin, Xu, Xiaoqiao, Kallurkar, Prajkta, Turinsky, Andrei L., Bear, Christine E., Ratjen, Felix, Kalish, Brian, Goyal, Sidhartha, Moraes, Theo J., Wong, Amy P.

“…Studying human fetal lungs can inform how developmental defects and disease states alter the function of the lungs. Here, we sequenced >150,000 single cells…”
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Orkambi® and amplifier co‐therapy improves function from a rare CFTR mutation in gene‐edited cells and patient tissue by Molinski, Steven V, Ahmadi, Saumel, Ip, Wan, Ouyang, Hong, Villella, Adriana, Miller, John P, Lee, Po‐Shun, Kulleperuma, Kethika, Du, Kai, Di Paola, Michelle, Eckford, Paul DW, Laselva, Onofrio, Huan, Ling Jun, Wellhauser, Leigh, Li, Ellen, Ray, Peter N, Pomès, Régis, Moraes, Theo J, Gonska, Tanja, Ratjen, Felix, Bear, Christine E

“…The combination therapy of lumacaftor and ivacaftor (Orkambi ® ) is approved for patients bearing the major cystic fibrosis (CF) mutation: ΔF508 . It has been…”
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Maternal consumption of artificially sweetened beverages during pregnancy is associated with infant gut microbiota and metabolic modifications and increased infant body mass index by Laforest-Lapointe, Isabelle, Becker, Allan B., Mandhane, Piushkumar J., Turvey, Stuart E., Moraes, Theo J., Sears, Malcolm R., Subbarao, Padmaja, Sycuro, Laura K., Azad, Meghan B., Arrieta, Marie-Claire

“…Artificial sweetener consumption by pregnant women has been associated with an increased risk of infant obesity, but the underlying mechanisms are unknown. We…”
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