Search Results - "MOORE, L. MERKLE"

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  1. 1

    A new animal model of insulin-glucose dynamics in the intraperitoneal space enhances closed-loop control performance by Chakrabarty, Ankush, Gregory, Justin M., Moore, L. Merkle, Williams, Philip E., Farmer, Ben, Cherrington, Alan D., Lord, Peter, Shelton, Brian, Cohen, Don, Zisser, Howard C., Doyle, Francis J., Dassau, Eyal

    Published in Journal of process control (01-04-2019)
    “…•State-of-the-art control algorithms delivering insulin subcutaneously (SC) to treat type 1 diabetes (T1D) exhibit slow diffusion and lag.•Alternative insulin…”
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    Journal Article
  2. 2

    Case Report: Syndrome of Remitting Seronegative Symmetrical Synovitis with Pitting Edema—A Rare but Treatable Condition in Palliative Medicine by Moore, L Merkle, Brouner, Jennifer M, Grigorian, Nelly, Leach, R J, Baumrucker, Steven J

    Published in Palliative medicine reports (01-12-2022)
    “…The syndrome of remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a rare diagnosis that is often missed due to lack of both definitive…”
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    Journal Article
  3. 3

    The kinetics of glucagon action on the liver during insulin-induced hypoglycemia by Pedersen, Christina, Kraft, Guillaume, Edgerton, Dale S, Scott, Melanie, Farmer, Ben, Smith, Marta, Laneve, David C, Williams, Phillip E, Moore, L Merkle, Cherrington, Alan D

    “…Glucagon's effect on hepatic glucose production (HGP), under hyperglycemic conditions, is time dependent such that after an initial burst of HGP, it slowly…”
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    Journal Article
  4. 4

    1801-P: Common Hepatic Artery Denervation Does Not Alter the Counterregulatory Response to Hypoglycemia in an Insulin Resistant Canine Model by KRAFT, GUILLAUME, MOORE, L. MERKLE, FARMER, BEN, SCOTT, MELANIE F., EDGERTON, DALE S., WILLIAMS, PHILLIP E., AZAMIAN, BOBAK, CHERRINGTON, ALAN D.

    Published in Diabetes (New York, N.Y.) (01-06-2019)
    “…With the recent interest in sympathetic modulation as a way to improve insulin sensitivity and insulin secretion, it is important to assess the safety of the…”
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    Journal Article
  5. 5

    Enterically delivered insulin tregopil exhibits rapid absorption characteristics and a pharmacodynamic effect similar to human insulin in conscious dogs by Gregory, Justin M., Lautz, Margaret, Moore, Lindsey M., Williams, Phillip E., Reddy, Praveen, Cherrington, Alan D.

    Published in Diabetes, obesity & metabolism (01-01-2019)
    “…Aims Current therapy fails to emulate rapid (first‐phase) insulin release in relation to a meal, a key defect in types 1 and 2 diabetes. We aimed to quantify…”
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    Journal Article
  6. 6

    Incretin Hormone Release Does Not Involve Hepatic Portal Vein Glucose Sensors by EDGERTON, DALE S., KRAFT, GUILLAUME, SMITH, MARTA S., MERKLE MOORE, L., FARMER, BEN, SARA, HEATHER, SCOTT, MELANIE, MOORE, MARY, NAUCK, MICHAEL A., CHERRINGTON, ALAN D.

    Published in Diabetes (New York, N.Y.) (01-07-2018)
    “…The incretin effect, which is defective in individuals with T2D, involves the secretion of GLP-1 and GIP when glucose is given orally, but not when it is…”
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    Journal Article
  7. 7

    Basal Oral Insulin Analog I338 Enhances Meal-Related Hepatic Glucose Disposal by MOORE, MARY C., NISHIMURA, ERICA, BRAND, CHRISTIAN L., KJELDSEN, THOMAS, MADSEN, PETER, REFSGAARD, HANNE H., WASSERMANN, KARSTEN, GRAM-NIELSEN, SANNE, SMITH, MARTA S., MOORE, L. MERKLE, FARMER, BEN, HASTINGS, JON R., WILLIAMS, PHILLIP E., CHERRINGTON, ALAN D.

    Published in Diabetes (New York, N.Y.) (01-07-2018)
    “…Oral insulin avoids the need for injections, and insulin enters via the hepatic portal vein (Po), the normal route of secretion. We examined the effect of…”
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    Journal Article
  8. 8