Search Results - "MONTESSUIT, CHRISTOPHE"

Regulation and dysregulation of glucose transport in cardiomyocytes by Montessuit, Christophe, Lerch, René

“…The ability of the heart muscle to derive energy from a wide variety of substrates provides the myocardium with remarkable capacity to adapt to the…”
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Cardiac metabolism as a driver and therapeutic target of myocardial infarction by Zuurbier, Coert J., Bertrand, Luc, Beauloye, Christoph R., Andreadou, Ioanna, Ruiz‐Meana, Marisol, Jespersen, Nichlas R., Kula‐Alwar, Duvaraka, Prag, Hiran A., Eric Botker, Hans, Dambrova, Maija, Montessuit, Christophe, Kaambre, Tuuli, Liepinsh, Edgars, Brookes, Paul S., Krieg, Thomas

“…Reducing infarct size during a cardiac ischaemic‐reperfusion episode is still of paramount importance, because the extension of myocardial necrosis is an…”
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Differential intracellular management of fatty acids impacts on metabolic stress-stimulated glucose uptake in cardiomyocytes by Vanni, Ettore, Lindner, Karina, Gavin, Anne-Claude, Montessuit, Christophe

“…Stimulation of glucose uptake in response to ischemic metabolic stress is important for cardiomyocyte function and survival. Chronic exposure of cardiomyocytes…”
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Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury by Braunersreuther, Vincent, Montecucco, Fabrizio, Ashri, Mohammed, Pelli, Graziano, Galan, Katia, Frias, Miguel, Burger, Fabienne, Quinderé, Ana Luíza Gomez, Montessuit, Christophe, Krause, Karl-Heinz, Mach, François, Jaquet, Vincent

“…Abstract Myocardial reperfusion injury is mediated by several processes including increase of reactive oxygen species (ROS). The aim of the study is to…”
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Detecting early myocardial ischemia in rat heart by MALDI imaging mass spectrometry by Aljakna Khan, Aleksandra, Bararpour, Nasim, Gorka, Marie, Joye, Timothée, Morel, Sandrine, Montessuit, Christophe A., Grabherr, Silke, Fracasso, Tony, Augsburger, Marc, Kwak, Brenda R., Thomas, Aurélien, Sabatasso, Sara

“…Diagnostics of myocardial infarction in human post-mortem hearts can be achieved only if ischemia persisted for at least 6–12 h when certain morphological…”
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Cold Exposure Rejuvenates the Metabolic Phenotype of Panx1 -/- Mice by Molica, Filippo, Ehrlich, Avigail, Pelli, Graziano, Rusiecka, Olga M, Montessuit, Christophe, Chanson, Marc, Kwak, Brenda R

“…Pannexin1 (Panx1) ATP channels are important in adipocyte biology, potentially influencing energy storage and expenditure. We compared the metabolic phenotype…”
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Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction by Montecucco, Fabrizio, Bauer, Inga, Braunersreuther, Vincent, Bruzzone, Santina, Akhmedov, Alexander, Lüscher, Thomas F, Speer, Timo, Poggi, Alessandro, Mannino, Elena, Pelli, Graziano, Galan, Katia, Bertolotto, Maria, Lenglet, Sébastien, Garuti, Anna, Montessuit, Christophe, Lerch, René, Pellieux, Corinne, Vuilleumier, Nicolas, Dallegri, Franco, Mage, Jacqueline, Sebastian, Carlos, Mostoslavsky, Raul, Gayet-Ageron, Angèle, Patrone, Franco, Mach, François, Nencioni, Alessio

“…Nicotinamide phosphoribosyltransferase (Nampt) is a key enzyme for nicotinamide adenine dinucleotide (NAD(+)) biosynthesis, and recent evidence indicates its…”
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Free Fatty Acids Impair FGF21 Action in HepG2 Cells by Asrih, Mohamed, Montessuit, Christophe, Philippe, Jacques, Jornayvaz, François R.

“…Background/Aims: Fibroblast growth factor 21 (FGF21) is a key mediator of glucose and lipid metabolism. However, the beneficial effects of exogenous FGF21…”
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Single Administration of the CXC Chemokine-Binding Protein Evasin-3 During Ischemia Prevents Myocardial Reperfusion Injury in Mice by Montecucco, Fabrizio, Lenglet, Sébastien, Braunersreuther, Vincent, Pelli, Graziano, Pellieux, Corinne, Montessuit, Christophe, Lerch, René, Deruaz, Maud, Proudfoot, Amanda E, Mach, François

“…OBJECTIVE—Evasins (chemokine-binding proteins) have been shown to selectively neutralize chemokine bioactivity. We investigated the potential benefits of…”
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Forkhead Transcription Factors Coordinate Expression of Myocardial KATP Channel Subunits and Energy Metabolism by Philip-Couderc, Pierre, Tavares, Nadia Isidoro, Roatti, Angela, Lerch, René, Montessuit, Christophe, Baertschi, Alex J

“…Coordinate adaptation of myocyte metabolism and function is fundamental to survival of the stressed heart, but the mechanisms for this coordination remain…”
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Transcriptional Activation of the Glucose Transporter GLUT1 in Ventricular Cardiac Myocytes by Hypertrophic Agonists by Montessuit, C, Thorburn, A

“…Myocardial hypertrophy is associated with increased basal glucose metabolism. Basal glucose transport into cardiac myocytes is mediated by the GLUT1 isoform of…”
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A Role for Focal Adhesion Kinase in the Stimulation of Glucose Transport in Cardiomyocytes by Viglino, Christelle, Montessuit, Christophe

“…ABSTRACT Stimulation of glucose transport is markedly impaired in cardiomyocytes exposed to free fatty acids (FFA), despite relative preservation of canonical…”
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Chronic AICAR treatment prevents metabolic changes in cardiomyocytes exposed to free fatty acids by Viglino, Christelle, Foglia, Bernard, Montessuit, Christophe

“…The stimulation of glucose transport by metabolic stress is an important determinant of myocardial susceptibility to ischemia and reperfusion injury…”
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Neuregulin-1 triggers GLUT4 translocation and enhances glucose uptake independently of insulin receptor substrate and ErbB3 in neonatal rat cardiomyocytes by Heim, Philippe, Morandi, Christian, Brouwer, Gian R., Xu, Lifen, Montessuit, Christophe, Brink, Marijke

“…During stress conditions such as pressure overload and acute ischemia, the myocardial endothelium releases neuregulin-1β (NRG-1), which acts as a…”
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Activation of a HIF1α-PPARγ Axis Underlies the Integration of Glycolytic and Lipid Anabolic Pathways in Pathologic Cardiac Hypertrophy by Krishnan, Jaya, Suter, Marianne, Windak, Renata, Krebs, Tatiana, Felley, Allison, Montessuit, Christophe, Tokarska-Schlattner, Malgorzata, Aasum, Ellen, Bogdanova, Anna, Perriard, Evelyne, Perriard, Jean-Claude, Larsen, Terje, Pedrazzini, Thierry, Krek, Wilhelm

“…Development of cardiac hypertrophy and progression to heart failure entails profound changes in myocardial metabolism, characterized by a switch from fatty…”
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Pleiotropic Effects of Chronic Phorbol Ester Treatment to Improve Glucose Transport in Insulin‐Resistant Cardiomyocytes by Viglino, Christelle, Khoramdin, Bahareh, Praplan, Guillaume, Montessuit, Christophe

“…ABSTRACT Stimulation of glucose transport is an important determinant of myocardial susceptibility to ischemia and reperfusion. Stimulation of glucose…”
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0366: A role for focal adhesion kinase in the stimulation of glucose transport in cardiomyocytes by Montessuit, Christophe

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Chemokine CCL5/RANTES inhibition reduces myocardial reperfusion injury in atherosclerotic mice by Braunersreuther, Vincent, Pellieux, Corinne, Pelli, Graziano, Burger, Fabienne, Steffens, Sabine, Montessuit, Christophe, Weber, Christian, Proudfoot, Amanda, Mach, François, Arnaud, Claire

“…Abstract Although beneficial for cardiomyocyte salvage and to limit myocardial damage and cardiac dysfunction, restoration of blood flow after prolonged…”
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Angiotensin II downregulates the fatty acid oxidation pathway in adult rat cardiomyocytes via release of tumour necrosis factor-α by Pellieux, Corinne, Montessuit, Christophe, Papageorgiou, Irène, Lerch, René

“…Aims Advanced heart failure is often associated with reduced myocardial fatty acid oxidation capacity. We have previously observed that failing hearts of mice…”
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Differential regulation of stimulated glucose transport by free fatty acids and PPARα or -δ agonists in cardiac myocytes by Asrih, Mohamed, Lerch, René, Papageorgiou, Irène, Pellieux, Corinne, Montessuit, Christophe

“…Stimulation of glucose transport in response to insulin or metabolic stress is an important determinant of cardiac myocyte function and survival, particularly…”
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