Search Results - "MONTE, Nicolas M"
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Emergence, Involution, and Progression to Carcinoma of Mutant Clones in Normal Endometrial Tissues
Published in Cancer research (Chicago, Ill.) (15-05-2014)“…Sporadic somatic inactivation of genes such as PTEN within histologically normal endometrium (latent precancers) is an early step in endometrial…”
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Joint Loss of PAX2 and PTEN Expression in Endometrial Precancers and Cancer
Published in Cancer research (Chicago, Ill.) (01-08-2010)“…Latent endometrial carcinoma precancers are normal-appearing endometrial glands with sporadic loss of tumor suppressor gene function such as PTEN. Progression…”
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3
High-grade fimbrial-ovarian carcinomas are unified by altered p53, PTEN and PAX2 expression
Published in Modern pathology (01-10-2010)“…High-grade endometrioid and serous carcinomas of the ovary and fallopian tube are responsible for the majority of cancer deaths and comprise a spectrum that…”
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Utility of PAX2 as a Marker for Diagnosis of Endometrial Intraepithelial Neoplasia
Published in American journal of clinical pathology (01-11-2012)“…Diagnosis of endometrial intraepithelial neoplasia (EIN) requires learning new criteria. Two trainees rendered diagnoses based on biopsy findings, and then…”
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Endometrial intraepithelial neoplasia with secretory differentiation: diagnostic features and underlying mechanisms
Published in Modern pathology (01-06-2013)“…Endometrial intraepithelial neoplasia (EIN) with secretory differentiation and ordinary EIN occurring in a secretory context are rare but recognized findings…”
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Dyssynchronous Secretory Endometrial Glands Often Show Sporadically Acquired Progesterone Nonresponsiveness
Published in International journal of gynecological pathology (01-05-2015)“…Primary sporadic gene-inactivating events within the progesterone response cascade might explain the presence of individual dyssynchronous (outlier) glands…”
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Digital quantification of precursor frequency in the fallopian tube and its significance
Published in Modern pathology (01-12-2012)“…A high frequency of precursor lesions is a risk factor for cancer in many organ systems but must be precisely quantified. Pelvic serous neoplasia is associated…”
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