Search Results - "MONCADA, SALVADOR"

Glycolysis: a bioenergetic or a survival pathway? by Bolaños, Juan P., Almeida, Angeles, Moncada, Salvador

“…Following inhibition of mitochondrial respiration neurons die rapidly, whereas astrocytes utilize glycolytically-generated ATP to increase their mitochondrial…”
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The Third Version of the Copenhagen Psychosocial Questionnaire by Burr, Hermann, Berthelsen, Hanne, Moncada, Salvador, Nübling, Matthias, Dupret, Emilie, Demiral, Yucel, Oudyk, John, Kristensen, Tage S., Llorens, Clara, Navarro, Albert, Lincke, Hans-Joachim, Bocéréan, Christine, Sahan, Ceyda, Smith, Peter, Pohrt, Anne

“…A new third version of the Copenhagen Psychosocial Questionnaire (COPSOQ III) has been developed in response to trends in working life, theoretical concepts,…”
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The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1 by Bolaños, Juan P, Herrero-Mendez, Angel, Almeida, Angeles, Fernández, Emilio, Moncada, Salvador, Maestre, Carolina

“…Neurons are known to have a lower glycolytic rate than astrocytes and when stressed they are unable to upregulate glycolysis because of low Pfkfb3…”
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Nitric oxide, cell bioenergetics and neurodegeneration by Moncada, Salvador, Bolaños, Juan P.

“…Following stimulation of NMDA receptors, neurons transiently synthesize nitric oxide (NO) in a calcium/calmodulin‐dependent manner through the activation of…”
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S-Nitrosation of Mitochondrial Complex I Depends on Its Structural Conformation by Galkin, Alexander, Moncada, Salvador

“…Nitric oxide is known to cause persistent inhibition of mitochondrial respiration as a result of S-nitrosation of NADH: ubiquinone oxidoreductase (complex I)…”
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E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation by Almeida, Angeles, Bolaños, Juan P, Moncada, Salvador

“…Cell proliferation is known to be accompanied by activation of glycolysis. We have recently discovered that the glycolysis-promoting enzyme…”
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Persistent inequality: evolution of psychosocial exposures at work among the salaried population in Spain between 2005 and 2016 by Utzet, Mireia, Llorens, Clara, Moriña, David, Moncada, Salvador

“…Purpose To assess the prevalence of poor mental health and of exposure to psychosocial risks among the working population in Spain in 2005, 2010 and 2016; to…”
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Delegation and consultation on operational and tactical issues: Any difference in their potentialities for a healthier psychosocial work environment? by Llorens‐Serrano, Clara, Salas‐Nicás, Sergio, Navarro‐Giné, Albert, Lluís, Salvador Moncada

“…Background Despite the growing number of studies on direct participation labor‐management practices, little is known about the role of their different…”
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Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells by Colombo, Sergio L, Palacios-Callender, Miriam, Frakich, Nanci, Carcamo, Saul, Kovacs, Istvan, Tudzarova, Slavica, Moncada, Salvador

“…During cell division, the activation of glycolysis is tightly regulated by the action of two ubiquitin ligases, anaphase-promoting complex/cyclosome–Cdh1…”
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The Employment Precariousness Scale (EPRES): psychometric properties of a new tool for epidemiological studies among waged and salaried workers by Vives, Alejandra, Amable, Marcelo, Ferrer, Montserrat, Moncada, Salvador, Llorens, Clara, Muntaner, Carles, Benavides, Fernando G, Benach, Joan

“…BackgroundDespite the fact that labour market flexibility has resulted in an expansion of precarious employment in industrialised countries, to date there is…”
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Calorie Restriction Promotes Mitochondrial Biogenesis by Inducing the Expression of eNOS by Nisoli, Enzo, Tonello, Cristina, Cardile, Annalisa, Cozzi, Valeria, Bracale, Renata, Tedesco, Laura, Falcone, Sestina, Valerio, Alessandra, Cantoni, Orazio, Clementi, Emilio, Moncada, Salvador, Carruba, Michele O

“…Calorie restriction extends life span in organisms ranging from yeast to mammals. Here, we report that calorie restriction for either 3 or 12 months induced…”
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Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway by Moncada, Salvador, Almeida, Angeles, Bolaños, Juan P

“…After inhibition of cytochrome c oxidase by nitric oxide, astrocytes maintain energy production by upregulating glycolysis - a response which does not seem to…”
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Validation of the medium and short version of CENSOPAS-COPSOQ: a psychometric study in the Peruvian population by Lucero-Perez, Martha R, Sabastizagal, Iselle, Astete-Cornejo, Jonh, Burgos, Miguel Angel, Villarreal-Zegarra, David, Moncada, Salvador

“…The presence of psychosocial risks at work are associated with mental and physical health issues in workers. The study aim was to adapt the COPSOQ-ISTAS21…”
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Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-β-TrCP, sequentially regulate glycolysis during the cell cycle by Tudzarova, Slavica, Colombo, Sergio L., Stoeber, Kai, Carcamo, Saul, Williams, Gareth H., Moncada, Salvador

“…During cell proliferation, the abundance of the glycolysis-promoting enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, isoform 3 (PFKFB3), is…”
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Measuring precarious employment in times of crisis: the revised Employment Precariousness Scale (EPRES) in Spain by Vives, Alejandra, González, Francisca, Moncada, Salvador, Llorens, Clara, Benach, Joan

“…Abstract Objective This study examines the psychometric properties of the revised Employment Precariousness Scale (EPRES-2010) in a context of economic crisis…”
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Mitochondria as Signaling Organelles in the Vascular Endothelium by Quintero, Marisol, Colombo, Sergio L., Godfrey, Andrew, Moncada, Salvador

“…Vascular endothelial cells are highly glycolytic and consume relatively low amounts of oxygen (O₂) compared with other cells. We have confirmed that oxidative…”
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Inflammation, glucose, and vascular cell damage: the role of the pentose phosphate pathway by Peiró, Concepción, Romacho, Tania, Azcutia, Verónica, Villalobos, Laura, Fernández, Emilio, Bolaños, Juan P, Moncada, Salvador, Sánchez-Ferrer, Carlos F

“…Hyperglycemia is acknowledged as a pro-inflammatory condition and a major cause of vascular damage. Nevertheless, we have previously described that high…”
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Prevalence, associated factors and reasons for sickness presenteeism: a cross-sectional nationally representative study of salaried workers in Spain, 2016 by Navarro, Albert, Salas-Nicás, Sergio, Moncada, Salvador, Llorens, Clara, Molinero-Ruiz, Emilia

“…ObjectivesThe aim of this study was to estimate the prevalence of sickness presenteeism (SP), its associated factors and the reasons given for SP episodes,…”
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Employment Precariousness and Poor Mental Health: Evidence from Spain on a New Social Determinant of Health by Vives, Alejandra, Amable, Marcelo, Ferrer, Montserrat, Moncada, Salvador, Llorens, Clara, Muntaner, Carles, Benavides, Fernando G., Benach, Joan

“…Background. Evidence on the health-damaging effects of precarious employment is limited by the use of one-dimensional approaches focused on employment…”
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Nitric oxide favours tumour-promoting inflammation through mitochondria-dependent and -independent actions on macrophages by Drehmer, Daiana, Mesquita Luiz, João Paulo, Hernandez, Cesar Augusto Speck, Alves-Filho, José Carlos, Hussell, Tracy, Townsend, Paul Andrew, Moncada, Salvador

“…Production of nitric oxide (NO) has been demonstrated in several malignancies, however its role remains not fully understood, specifically in relation to the…”
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