Search Results - "MONATH, T"

Safety and Efficacy of Chimeric Yellow Fever-Dengue Virus Tetravalent Vaccine Formulations in Nonhuman Primates by GUIRAKHOO, F, PUGACHEV, K, BROWN, N, BRANDLER, S, FOURNIER, C, BARRERE, B, RIZVI, F, TRAVASSOS, A, NICHOLS, R, TRENT, D, MONATH, T, ZHANG, Z, MYERS, G, LEVENBOOK, I, DRAPER, K, LANG, J, OCRAN, S, MITCHELL, F, PARSONS, M

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Dengue: The Risk to Developed and Developing Countries by Monath, Thomas P.

“…Dengue viruses are members of the Flaviviridae, transmitted principally in a cycle involving humans and mosquito vectors. In the last 20 years the incidence of…”
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Challenge model for Helicobacter pylori infection in human volunteers by Graham, D Y, Opekun, A R, Osato, M S, El-Zimaity, H M T, Lee, C K, Yamaoka, Y, Qureshi, W A, Cadoz, M, Monath, T P

“…Background: A reliable challenge model is needed to evaluate Helicobacter pylori vaccine candidates. Methods: A cag pathogenicity island negative, OipA…”
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Japanese encephalitis vaccines: current vaccines and future prospects by Monath, T P

“…Vaccination against JE ideally should be practiced in all areas of Asia where the virus is responsible for human disease. The WHO has placed a high priority on…”
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Construction, Safety, and Immunogenicity in Nonhuman Primates of a Chimeric Yellow Fever-Dengue Virus Tetravalent Vaccine by Guirakhoo, F, Arroyo, J, Pugachev, K V, Miller, C, Zhang, Z X, Weltzin, R, Georgakopoulos, K, Catalan, J, Ocran, S, Soike, K, Ratterree, M, Monath, T P

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Safety and immunogenicity of the rVSV∆G-ZEBOV-GP Ebola virus vaccine candidate in healthy adults: a phase 1b randomised, multicentre, double-blind, placebo-controlled, dose-response study by Heppner, D Gray, Dr, Kemp, Tracy L, MPH, Martin, Brian K, PhD, Ramsey, William J, MD, Nichols, Richard, MA, Dasen, Emily J, BA, Link, Charles J, MD, Das, Rituparna, MD, Xu, Zhi Jin, PhD, Sheldon, Eric A, MD, Nowak, Teresa A, BSE, Monath, Thomas P, MD

“…Summary Background The 2014 Zaire Ebola virus outbreak highlighted the need for a safe, effective vaccine with a rapid onset of protection. We report the…”
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Recombinant Chimeric Yellow Fever-Dengue Type 2 Virus Is Immunogenic and Protective in Nonhuman Primates by Guirakhoo, F, Weltzin, R, Chambers, T J, Zhang, Z X, Soike, K, Ratterree, M, Arroyo, J, Georgakopoulos, K, Catalan, J, Monath, T P

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Safety and efficacy of low dose Escherichia coli enterotoxin adjuvant for urease based oral immunisation against Helicobacter pylori in healthy volunteers by Banerjee, S, Medina-Fatimi, A, Nichols, R, Tendler, D, Michetti, M, Simon, J, Kelly, C P, Monath, T P, Michetti, P

“…Background and aims:Escherichia coli heat labile enterotoxin (LT) at doses of 5 μg or 10 μg has adjuvant activity for oral immunisation in humans infected with…”
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Recombinant, chimaeric live, attenuated vaccine (ChimeriVax™) incorporating the envelope genes of Japanese encephalitis (SA14-14-2) virus and the capsid and nonstructural genes of yellow fever (17D) virus is safe, immunogenic and protective in non-human primates by Monath, T.P, Soike, K, Levenbook, I, Zhang, Z.-X, Arroyo, J, Delagrave, S, Myers, G, Barrett, A.D.T, Shope, R.E, Ratterree, M, Chambers, T.J, Guirakhoo, F

“…Yellow fever 17D virus, a safe and effective live, attenuated vaccine, was used as a vector for genes encoding the protective antigenic determinants of a…”
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Yellow fever as an endemic/epidemic disease and priorities for vaccination by MONATH, T. P

“…Yellow fever is a potentially fatal viral hemorrhagic fever. Although an effective vaccine (yellow fever 17D) has been available since the late 1930s,…”
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Viremia and Immunogenicity in Nonhuman Primates of a Tetravalent Yellow Fever–Dengue Chimeric Vaccine: Genetic Reconstructions, Dose Adjustment, and Antibody Responses against Wild-type Dengue Virus Isolates by Guirakhoo, F., Pugachev, K., Arroyo, J., Miller, C., Zhang, Z.-X., Weltzin, R., Georgakopoulos, K., Catalan, J., Ocran, S., Draper, K., Monath, T.P.

“…Chimeric yellow fever (YF)–dengue (DEN) viruses (ChimeriVax–DEN) were reconstructed to correct amino acid substitutions within the envelope genes of original…”
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Oral immunization with urease and Escherichia coli heat-labile enterotoxin is safe and immunogenic in Helicobacter pylori–infected adults by Michetti, Pierre, Kreiss, Christianna, Kotloff, Karen L., Porta, Nadine, Blanco, José–Luis, Bachmann, Daniel, Herranz, Maribelle, Saldinger, Pierre F., Corthésy–Theulaz, Irène, Losonsky, Geneviève, Nichols, Richard, Simon, Joseph, Stolte, Manfred, Ackerman, Samuel, Monath, Thomas P., Blum, André L.

“…Background & Aims: Oral immunization with Helicobacter pylori urease can cure Helicobacter infection in animals. As a step toward therapeutic immunization in…”
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A Single Amino Acid Substitution in the Envelope Protein of Chimeric Yellow Fever-Dengue 1 Vaccine Virus Reduces Neurovirulence for Suckling Mice and Viremia/Viscerotropism for Monkeys by GUIRAKHOO, F, ZHANG, Z, LANG, J, FOURNIER, C, BARRERE, B, DELAGRAVE, S, MONATH, T. P, MYERS, G, JOHNSON, B. W, PUGACHEV, K, NICHOLS, R, BROWN, N, LEVENBOOK, I, DRAPER, K, CYREK, S

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Chimeric Yellow Fever Virus 17D-Japanese Encephalitis Virus Vaccine: Dose-Response Effectiveness and Extended Safety Testing in Rhesus Monkeys by Monath, T P, Levenbook, I, Soike, K, Zhang, Z X, Ratterree, M, Draper, K, Barrett, A D, Nichols, R, Weltzin, R, Arroyo, J, Guirakhoo, F

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Molecular Basis for Attenuation of Neurovirulence of a Yellow Fever Virus/Japanese Encephalitis Virus Chimera Vaccine (ChimeriVax-JE) by Arroyo, J, Guirakhoo, F, Fenner, S, Zhang, Z X, Monath, T P, Chambers, T J

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Immunogenicity, Genetic Stability, and Protective Efficacy of a Recombinant, Chimeric Yellow Fever-Japanese Encephalitis Virus (ChimeriVax-JE) as a Live, Attenuated Vaccine Candidate against Japanese Encephalitis by Guirakhoo, F., Zhang, Z.-X., Chambers, T.J., Delagrave, S., Arroyo, J., Barrett, A.D.T., Monath, T.P.

“…Yellow fever (YF) 17D vaccine virus, having a 60-year history of safe and effective use, is an ideal vector to deliver heterologous genes from other medically…”
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Prospects for Development of a Vaccine against the West Nile Virus by MONATH, THOMAS P.

“…: Vaccination provides the ultimate measure for personal protection against West Nile disease. The development of a West Nile vaccine for humans is justified…”
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Safety and immunogenicity of increasing doses of a Clostridium difficile toxoid vaccine administered to healthy adults by KOTLOFF, Karen L, WASSERMAN, Steven S, LOSONSKY, Genevieve A, THOMAS, William JR, NICHOLS, Richard, EDELMAN, Robert, BRIDWELL, Margaret, MONATH, Thomas P

“…Clostridium difficile is a major cause of nosocomial diarrhea in industrialized countries. Although most illnesses respond to available therapy, infection can…”
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Prevention of Yellow Fever in Persons Traveling to the Tropics by Monath, Thomas P., Cetron, Martin S.

“…Yellow fever (YF) is a potentially lethal mosquito-borne viral hemorrhagic fever endemic in Africa and South America. Nine million tourists annually arrive in…”
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Chimeric Live, Attenuated Vaccine against Japanese Encephalitis (ChimeriVax-JE): Phase 2 Clinical Trials for Safety and Immunogenicity, Effect of Vaccine Dose and Schedule, and Memory Response to Challenge with Inactivated Japanese Encephalitis Antigen by Monath, Thomas P., Guirakhoo, Farshad, Nichols, Richard, Yoksan, Sutee, Schrader, Robert, Murphy, Chris, Blum, Paul, Woodward, Stephen, McCarthy, Karen, Mathis, Danell, Johnson, Casey, Bedford, Philip

“…ChimeriVax-JE is a live, attenuated vaccine against Japanese encephalitis, using yellow fever (YF) 17D vaccine as a vector. In a double-blind phase 2 trial, 99…”
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