Search Results - "MOMOSE, Kazuhiro"
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Both V1A and V1B vasopressin receptors deficiency result in impaired glucose tolerance
Published in European journal of pharmacology (01-06-2009)Get full text
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Inactivation of a Novel Neuropeptide Y/Peptide YY Receptor Gene in Primate Species
Published in The Journal of biological chemistry (01-11-1996)“…Neuropeptide Y (NPY), peptide YY (PYY), and pancreatic polypeptide (PP) belong to a family of structurally related peptides which have numerous functions in…”
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Endomorphins have orexigenic and anxiolytic activities in mice
Published in Neuroreport (13-07-1998)“…THIS study was designed to investigate the effects of endomorphin 1 and 2, recently identified μ-opioid receptor selective peptides, on food intake and anxiety…”
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Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor
Published in Biochemical and biophysical research communications (28-01-2005)“…A lysophospholipid series, such as lysophosphatidic acid, lysophosphatidylserine, and lysophosphatidylcholine (LPC), is a bioactive lipid mediator with diverse…”
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Both V 1A and V 1B vasopressin receptors deficiency result in impaired glucose tolerance
Published in European journal of pharmacology (24-06-2009)“…[Arg 8]-vasopressin (AVP) is involved in the regulation of glucose homeostasis via vasopressin V 1A and vasopressin V 1B receptor. Our previous studies have…”
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Synthesis of 5-chloro-N-aryl-1H-indole-2-carboxamide derivatives as inhibitors of human liver glycogen phosphorylase a
Published in Bioorganic & medicinal chemistry (15-05-2008)“…A series of 5-chloro-N-aryl-1H-indole-2-carboxamide derivatives were prepared and evaluated as inhibitors of human liver glycogen phosphorylase a (hLGPa). One…”
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Identification of 4-quinolone derivatives as inhibitors of reactive oxygen species production from human umbilical vein endothelial cells
Published in Bioorganic & medicinal chemistry letters (15-11-2011)“…A series of substituted 4-quinolone derivatives were prepared and evaluated as inhibitors of reactive oxygen species (ROS) production from human umbilical vein…”
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Design, synthesis, and pharmacological evaluation of N-bicyclo-5-chloro-1H-indole-2-carboxamide derivatives as potent glycogen phosphorylase inhibitors
Published in Bioorganic & medicinal chemistry (01-12-2008)“…As a result of the various N-bicyclo-5-chloro-1H-indole-2-carboxamide derivatives with a hydroxy moiety synthesized in an effort to discover novel glycogen…”
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Synthesis and pharmacological evaluation of bis-3-(3,4-dichlorophenyl)acrylamide derivatives as glycogen phosphorylase inhibitors
Published in Bioorganic & medicinal chemistry (15-09-2008)“…(2 E,2′ E)- N, N′-Pentane-1,5-diylbis[3-(3,4-dichlorophenyl)acrylamide] and its heteroatom-containing analogues are potent inhibitors of human liver glycogen…”
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Hypoglycemic Agent YM440 Ameliorates the Impaired Hepatic Glycogenesis After Glucose Loading by Increasing Glycogen Synthase Activity in Obese Zucker Rats
Published in Japanese Journal of Pharmacology (2002)“…We studied the role of hepatic glycogenesis in glucose intolerance after glucose loading in obese Zucker rats and the effects of YM440…”
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Effects of YM218, a nonpeptide vasopressin V 1A receptor-selective antagonist, on vasopressin-induced growth responses in human mesangial cells
Published in European journal of pharmacology (24-05-2006)“…Mesangial cells are centrally-located glomerular pericytes with contractile, endocrine, and immunity-regulating functions. These cells are thought to maintain…”
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Effects of YM218, a nonpeptide vasopressin V(1A) receptor-selective antagonist, on vasopressin-induced growth responses in human mesangial cells
Published in European journal of pharmacology (24-05-2006)“…Mesangial cells are centrally-located glomerular pericytes with contractile, endocrine, and immunity-regulating functions. These cells are thought to maintain…”
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Synthesis of 5-chloro- N-aryl-1 H-indole-2-carboxamide derivatives as inhibitors of human liver glycogen phosphorylase a
Published in Bioorganic & medicinal chemistry (2008)“…5-Chloro- N-[4-(1,2-dihydroxyethyl)phenyl]-1 H-indole-2-carboxamide and its pyridine analog are potent inhibitors of human liver glycogen phosphorylase a…”
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Design, synthesis, and pharmacological evaluation of N-bicyclo-5-chloro-1 H-indole-2-carboxamide derivatives as potent glycogen phosphorylase inhibitors
Published in Bioorganic & medicinal chemistry (2008)“…5-Chloro- N-[(5 R)-1,3,6,6-tetrafluoro-5-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl]-1 H-indole-2-carboxamide are potent inhibitors of human liver glycogen…”
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Neuropeptide Y Produces Anxiety Via Y2-Type Receptors
Published in Peptides (New York, N.Y. : 1980) (01-01-1998)“…Nakajima, M., A. Inui, A. Asakawa, K. Momose, N. Ueno, A. Teranishi, S. Baba and M. Kasuga. Neuropeptide Y produces anxiety via Y2-type receptors. Peptides…”
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Hypoglycemic agent YM440 suppresses hepatic glucose output via gluconeogenesis by reducing glucose-6-phosphatase activity in obese Zucker rats
Published in European journal of pharmacology (09-05-2003)“…Using a glucose clamp, we had shown that YM440, ( Z)-1,4-bis{4-[(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)methyl]phenoxy}but-2-ene, reduced the increased hepatic…”
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Binding and signal transduction characteristics of the nonpeptide vasopressin V1A receptor-selective antagonist YM218 in cultured rat mesangial cells
Published in Pharmacology (2006)“…Vasopressin (AVP) causes mesangial cell contraction, proliferation and hypertrophy. The present study investigated the effects of YM218, a potent, nonpeptide…”
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