Search Results - "MOLVEN, ANDERS"
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A human clinical trial using ultrasound and microbubbles to enhance gemcitabine treatment of inoperable pancreatic cancer
Published in Journal of controlled release (10-12-2016)“…The primary aim of our study was to evaluate the safety and potential toxicity of gemcitabine combined with microbubbles under sonication in inoperable…”
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C/EBPB-dependent adaptation to palmitic acid promotes tumor formation in hormone receptor negative breast cancer
Published in Nature communications (10-01-2022)“…Epidemiological studies have established a positive association between obesity and the incidence of postmenopausal breast cancer. Moreover, it is known that…”
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Expression of the "stem cell marker" CD133 in pancreas and pancreatic ductal adenocarcinomas
Published in BMC cancer (08-02-2008)“…It has been suggested that a small population of cells with unique self-renewal properties and malignant potential exists in solid tumors. Such "cancer stem…”
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Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth
Published in Nature communications (01-10-2019)“…Infant and childhood growth are dynamic processes with large changes in BMI during development. By performing genome-wide association studies of BMI at 12 time…”
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Novel hybridization- and tag-based error-corrected method for sensitive ctDNA mutation detection using ion semiconductor sequencing
Published in Scientific reports (06-04-2022)“…Circulating tumor DNA (ctDNA) analysis has emerged as a clinically useful tool for cancer diagnostics and treatment monitoring. However, ctDNA detection is…”
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Targeted next-generation sequencing reveals MODY in up to 6.5% of antibody-negative diabetes cases listed in the Norwegian Childhood Diabetes Registry
Published in Diabetologia (01-04-2017)“…Aims/hypothesis MODY can be wrongly diagnosed as type 1 diabetes in children. We aimed to find the prevalence of MODY in a nationwide population-based registry…”
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Functional Investigations of HNF1A Identify Rare Variants as Risk Factors for Type 2 Diabetes in the General Population
Published in Diabetes (New York, N.Y.) (01-02-2017)“…Variants in HNF1A encoding hepatocyte nuclear factor 1α (HNF-1A) are associated with maturity-onset diabetes of the young form 3 (MODY 3) and type 2 diabetes…”
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Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling
Published in Scientific reports (17-05-2017)“…The majority of cancer patients with advanced disease experience weight loss, including loss of lean body mass. Severe weight loss is characteristic for cancer…”
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α11β1 Integrin is Induced in a Subset of Cancer-Associated Fibroblasts in Desmoplastic Tumor Stroma and Mediates In Vitro Cell Migration
Published in Cancers (01-06-2019)“…Integrin α11β1 is a collagen receptor that has been reported to be overexpressed in the stroma of non-small cell lung cancer (NSCLC) and of head and neck…”
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CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells
Published in International journal of cancer (15-02-2008)“…CD133 is a cell surface marker expressed on progenitors of haematopoietic and endothelial cell lineages. Moreover, several studies have identified CD133 as a…”
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The role of the carboxyl ester lipase (CEL) gene in pancreatic disease
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-01-2018)“…The enzyme carboxyl ester lipase (CEL), also known as bile salt-dependent or -stimulated lipase (BSDL, BSSL), hydrolyzes dietary fat, cholesteryl esters and…”
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Golgi-Localized PAQR4 Mediates Antiapoptotic Ceramidase Activity in Breast Cancer
Published in Cancer research (Chicago, Ill.) (01-06-2020)Get full text
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Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase
Published in Biochemistry (Easton) (23-08-2016)“…A recently discovered class of endogenous mammalian lipids, branched fatty acid esters of hydroxy fatty acids (FAHFAs), possesses anti-diabetic and…”
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U‐251 revisited: genetic drift and phenotypic consequences of long‐term cultures of glioblastoma cells
Published in Cancer medicine (Malden, MA) (01-08-2014)“…It is well known that in vitro subculture represents a selection pressure on cell lines, and over time this may result in a genetic drift in the cancer cells…”
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Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3
Published in Proceedings of the National Academy of Sciences - PNAS (12-01-2010)“…Genome-wide association studies identified noncoding SNPs associated with type 2 diabetes and obesity in linkage disequilibrium (LD) blocks encompassing…”
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Mutation analysis by deep sequencing of pancreatic juice from patients with pancreatic ductal adenocarcinoma
Published in BMC cancer (05-01-2019)“…Reliable methods are needed to identify patients with early-stage cancer or high-grade precancerous lesions in the pancreas. Analysis of pancreatic juice to…”
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Mutations in the Insulin Gene Can Cause MODY and Autoantibody-Negative Type 1 Diabetes
Published in Diabetes (New York, N.Y.) (01-04-2008)“…Mutations in the Insulin Gene Can Cause MODY and Autoantibody-Negative Type 1 Diabetes Anders Molven 1 2 , Monika Ringdal 3 4 , Anita M. Nordbø 3 4 , Helge…”
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Beta-Cell SCHAD Deficiency Causes Hypoglycemia in Mice
Published in Diabetes (New York, N.Y.) (01-07-2018)“…Congenital Hyperinsulinism of Infancy (CHI) is a group of rare, inheritable disorders with persistent hypoglycemia due to hyperinsulinemia. CHI is caused by…”
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Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction
Published in Nature genetics (01-01-2006)“…Dysfunction of the exocrine pancreas is observed in diabetes, but links between concurrent exocrine and endocrine pancreatic disease and contributing genetic…”
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