Search Results - "MOLIMARD, Mathieu"

Chronic obstructive pulmonary disease exacerbation and inhaler device handling: real-life assessment of 2935 patients by Molimard, Mathieu, Raherison, Chantal, Lignot, Severine, Balestra, Aurelie, Lamarque, Stephanie, Chartier, Anais, Droz-Perroteau, Cecile, Lassalle, Regis, Moore, Nicholas, Girodet, Pierre-Olivier

“…Acute exacerbations of chronic obstructive pulmonary disease (COPD) can be prevented by inhaled treatment. Errors in inhaler handling, not taken into account…”
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The scientific rationale for combining long-acting β2 -agonists and muscarinic antagonists in COPD by Cazzola, Mario, Molimard, Mathieu

“…Abstract Bronchodilators are the cornerstone of pharmacological management of COPD. For patients whose conditions are not sufficiently controlled by…”
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High throughput routine determination of 17 tyrosine kinase inhibitors by LC–MS/MS by Merienne, Camille, Rousset, Marine, Ducint, Dominique, Castaing, Nadège, Titier, Karine, Molimard, Mathieu, Bouchet, Stéphane

“…•The aim of this assay is to develop a tool to quantify tyrosine kinase inhibitors.•The tool must be fast with high throughput.•Solid phase extraction,…”
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Omalizumab effectiveness in patients with severe allergic asthma according to blood eosinophil count: the STELLAIR study by Humbert, Marc, Taillé, Camille, Mala, Laurence, Le Gros, Vincent, Just, Jocelyne, Molimard, Mathieu

“…Omalizumab is a monoclonal anti-IgE antibody used to treat severe allergic asthma (SAA). The aim of the STELLAIR study was to determine the importance of…”
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Adherence Is the Critical Factor for Achieving Molecular Responses in Patients With Chronic Myeloid Leukemia Who Achieve Complete Cytogenetic Responses on Imatinib by MARIN, David, BAZEOS, Alexandra, PALIOMPEIS, Christos, LATHAM, Victoria, FORONI, Letizia, MOLIMARD, Mathieu, REID, Alistair, REZVANI, Katy, DE LAVALLADE, Hugues, GUALLAR, Cristina, GOLDMAN, John, KHORASHAD, Jamshid S, MAHON, Francois-Xavier, ELIASSON, Lina, MILOJKOVIC, Dragana, BUA, Marco, APPERLEY, Jane F, SZYDLO, Richard, DESAI, Ritti, KOZLOWSKI, Kasia

“…There is a considerable variability in the level of molecular responses achieved with imatinib therapy in patients with chronic myeloid leukemia (CML). These…”
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Simultaneous determination of nine tyrosine kinase inhibitors by 96-well solid-phase extraction and ultra performance LC/MS-MS by Bouchet, Stéphane, Chauzit, Emmanuelle, Ducint, Dominique, Castaing, Nadège, Canal-Raffin, Mireille, Moore, Nicholas, Titier, Karine, Molimard, Mathieu

“…Tyrosine Kinase Inhibitors (TKIs) are a class of targeted drugs for the treatment of malignant pathologies. The metabolic profile of these drugs can result in…”
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Pazopanib plus best supportive care versus best supportive care alone in advanced gastrointestinal stromal tumours resistant to imatinib and sunitinib (PAZOGIST): a randomised, multicentre, open-label phase 2 trial by Mir, Olivier, MD, Cropet, Claire, MSc, Toulmonde, Maud, MD, Cesne, Axel Le, MD, Molimard, Mathieu, Prof, Bompas, Emmanuelle, MD, Cassier, Philippe, MD, Ray-Coquard, Isabelle, Prof, Rios, Maria, MD, Adenis, Antoine, Prof, Italiano, Antoine, MD, Bouché, Olivier, Prof, Chauzit, Emmanuelle, PharmD, Duffaud, Florence, Prof, Bertucci, François, Prof, Isambert, Nicolas, MD, Gautier, Julien, MSc, Blay, Jean-Yves, Prof, Pérol, David, MD

“…Summary Background Gastrointestinal stromal tumours (GIST) are the most common mesenchymal neoplasms of the gastrointestinal tract. Imatinib followed by…”
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Poor adherence is the main reason for loss of CCyR and imatinib failure for chronic myeloid leukemia patients on long-term therapy by Ibrahim, Amr R., Eliasson, Lina, Apperley, Jane F., Milojkovic, Dragana, Bua, Marco, Szydlo, Richard, Mahon, Francois-Xavier, Kozlowski, Kasia, Paliompeis, Christos, Foroni, Letizia, Khorashad, Jamshid S., Bazeos, Alex, Molimard, Mathieu, Reid, Alistair, Rezvani, Katayoun, Gerrard, Gareth, Goldman, John, Marin, David

“…We studied the relation between adherence to imatinib measured with microelectronic monitoring systems and the probabilities of losing a complete cytogenetic…”
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Nurses’ internal contamination by antineoplastic drugs in hospital centers: a cross-sectional descriptive study by Villa, Antoine, Molimard, Mathieu, Sakr, Dunia, Lassalle, Régis, Bignon, Emmanuelle, Martinez, Béatrice, Rouyer, Magali, Mathoulin-Pelissier, Simone, Baldi, Isabelle, Verdun-Esquer, Catherine, Canal-Raffin, Mireille

“…Objective The aim of this study was to assess internal antineoplastic drugs (ADs) contamination in the nursing staff in French hospital centers, using highly…”
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Trough dabrafenib plasma concentrations can predict occurrence of adverse events requiring dose reduction in metastatic melanoma by Rousset, Marine, Dutriaux, Caroline, Bosco-Lévy, Pauline, Prey, Sorilla, Pham-Ledard, Anne, Dousset, Léa, Gérard, Emilie, Bouchet, Stephane, Canal-Raffin, Mireille, Titier, Karine, Molimard, Mathieu

“…Dabrafenib and trametinib bitherapy provides significant benefits in BRAFV600mut metastatic melanoma patients; however, adverse events (AE) occur, leading to…”
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The sustainable impact of an educational approach to improve the appropriateness of laboratory test orders in the ICU by Clouzeau, Benjamin, Caujolle, Marie, San-Miguel, Aurelie, Pillot, Jerome, Gazeau, Nathalie, Tacaille, Christophe, Dousset, Vincent, Bazin, Fabienne, Vargas, Frederic, Hilbert, Gilles, Molimard, Mathieu, Gruson, Didier, Boyer, Alexandre

“…Few studies described strategies to improve the use of diagnostic tests in intensive care units (ICU). No study assessed whether their impact was sustained or…”
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Systematic review of association between critical errors in inhalation and health outcomes in asthma and COPD by Kocks, Janwillem W. H., Chrystyn, Henry, van der Palen, Job, Thomas, Mike, Yates, Louisa, Landis, Sarah H., Driessen, Maurice T., Gokhale, Mugdha, Sharma, Raj, Molimard, Mathieu

“…Inhaled medications are the cornerstone of treatment and management of asthma and COPD. However, inhaler device errors are common among patients and have been…”
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Highly sensitive LC–MS/MS methods for urinary biological monitoring of occupational exposure to cyclophosphamide, ifosfamide, and methotrexate antineoplastic drugs and routine application by Canal-Raffin, Mireille, Khennoufa, Karim, Martinez, Béatrice, Goujon, Yves, Folch, Celia, Ducint, Dominique, Titier, Karine, Brochard, Patrick, Verdun-Esquer, Catherine, Molimard, Mathieu

“…•Two highly sensitive methods in urine are proposed for healthcare professionals biomonitoring occupationaly exposed to antineoplastic drugs.•For…”
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Transition of care from adolescence to early adulthood in severe asthmatic patients treated with omalizumab in real life by Taillé, Camille, Humbert, Marc, Bourdin, Arnaud, Thonnelier, Céline, Lajoinie, Audrey, Chassetuillier, Jules, Molimard, Mathieu, Deschildre, Antoine

“…https://bit.ly/49ixpxt…”
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Comorbidities and COPD severity in a clinic-based cohort by Raherison, Chantal, Ouaalaya, El-Hassane, Bernady, Alain, Casteigt, Julien, Nocent-Eijnani, Cecilia, Falque, Laurent, Le Guillou, Frédéric, Nguyen, Laurent, Ozier, Annaig, Molimard, Mathieu

“…Chronic obstructive pulmonary disease (COPD) is an important cause of morbidity and mortality around the world. The aim of our study was to determine the…”
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Pharmacokinetics and Pharmacodynamics of Nilotinib in Gastrointestinal Stromal Tumors by Trent, Jonathan, Molimard, Mathieu

“…Nilotinib is a second-generation, oral tyrosine kinase inhibitor that provides specific inhibition of KIT, platelet-derived growth factor receptors (PDGFRs)…”
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Effectiveness of omalizumab (Xolair® ) in the first patients treated in real-life practice in France by Molimard, Mathieu, de Blay, Frédéric, Didier, Alain, Le Gros, Vincent

“…Summary Objective To describe omalizumab (Xolair® ) effectiveness in the first patients treated on compassionate grounds before its commercialisation in…”
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Correction to “Impact of liquid sublingual immunotherapy on asthma onset and progression in patients with allergic rhinitis: a nationwide population-based study (EfficAPSI study)” [The Lancet Regional Health – Europe 41 (2024) 100915] by Demoly, Pascal, Molimard, Mathieu, Bergmann, Jean-François, Delaisi, Bertrand, Gouverneur, Amandine, Vadel, Jade, Collin, Cédric, Girard, Laurence, Scurati, Silvia, Devillier, Philippe

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Therapeutic drug monitoring of imatinib in chronic myeloid leukemia: experience from 1216 patients at a centralized laboratory by Bouchet, Stéphane, Titier, Karine, Moore, Nicholas, Lassalle, Régis, Ambrosino, Basmah, Poulette, Sylvie, Schuld, Peter, Belanger, Coralie, Mahon, François-Xavier, Molimard, Mathieu

“…This study set out to examine in a large real‐life cohort of patients with chronic myeloid leukemia (CML) the impact of imatinib threshold of 1000 ng/mL on…”
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Impact of Patient-Related Factors on Asthma Control by Molimard, Mathieu, Le Gros, Vincent

“…Background. Patient-related factors are a significant component in the serious public health problem of poor asthma control, yet they have not been extensively…”
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