Search Results - "MOK, Tony Shu Kam"
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Pattern and impact of hepatic adverse events encountered during immune checkpoint inhibitors – A territory‐wide cohort study
Published in Cancer medicine (Malden, MA) (01-10-2020)“…Background Immune checkpoint inhibitors (ICIs) are increasingly used in the treatment of cancers. We aimed to evaluate the incidence and prognostic impact of…”
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Clinical Scoring System to Predict Hepatocellular Carcinoma in Chronic Hepatitis B Carriers
Published in Journal of clinical oncology (01-04-2010)“…Hepatitis B virus (HBV) infection is an important etiology for hepatocellular carcinoma (HCC). We aim to develop a simple clinical score in predicting the risk…”
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High Viral Load and Hepatitis B Virus Subgenotype Ce Are Associated With Increased Risk of Hepatocellular Carcinoma
Published in Journal of clinical oncology (10-01-2008)“…We aimed to investigate the impact of hepatitis B virus (HBV) DNA and HBV genotypes/subgenotypes on the risk of hepatocellular carcinoma (HCC). A prospective…”
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4
Therapeutic Strategies in EGFR Mutant Non-Small Cell Lung Cancer
Published in Current treatment options in oncology (01-11-2018)“…Opinion statement Non-small cell lung cancer (NSCLC) harboring epidermal growth receptor (EGFR) mutation has distinct genomic characteristics. Introduction of…”
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Baveno VII Criteria Is an Accurate Risk Stratification Tool to Predict High-Risk Varices Requiring Intervention and Hepatic Events in Patients with Advanced Hepatocellular Carcinoma
Published in Cancers (26-04-2023)“…The Baveno VII criteria are used in patients with liver cirrhosis to predict high-risk varices in patients with liver cirrhosis. Yet its use in patients with…”
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Distinct Molecular Landscape of Epstein–Barr Virus Associated Pulmonary Lymphoepithelioma-Like Carcinoma Revealed by Genomic Sequencing
Published in Cancers (01-08-2020)“…Pulmonary lymphoepithelioma-like carcinoma (LELC) is a subtype of non-small cell lung cancer (NSCLC) characterized by marked lymphocytic infiltration and…”
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Clinical activity of afatinib in patients with advanced non-small-cell lung cancer harbouring uncommon EGFR mutations: a combined post-hoc analysis of LUX-Lung 2, LUX-Lung 3, and LUX-Lung 6
Published in The lancet oncology (01-07-2015)“…Summary Background Most patients with non-small-cell lung cancer tumours that have EGFR mutations have deletion mutations in exon 19 or the Leu858Arg point…”
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Symposium: "Oncology Leadership in Asia"
Published in Cancer research and treatment (01-04-2017)“…The symposium on "Oncology Leadership in Asia" was held as part of the official program of the 42nd Annual Meeting of the Korean Cancer Association with…”
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A Memetic Algorithm for Multiple-Drug Cancer Chemotherapy Schedule Optimization
Published in IEEE transactions on systems, man and cybernetics. Part B, Cybernetics (01-02-2007)“…This correspondence introduces a multidrug cancer chemotherapy model to simulate the possible response of the tumor cells under drug administration. We…”
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Hepatitis Flare During Immunotherapy in Patients With Current or Past Hepatitis B Virus Infection
Published in The American journal of gastroenterology (01-06-2021)“…Immunotherapy has dramatically improved the survival of patients with advanced or metastatic malignancies. Recent studies suggest that immunotherapy may…”
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Application of classification tree and neural network algorithms to the identification of serological liver marker profiles for the diagnosis of hepatocellular carcinoma
Published in Oncology (01-01-2001)“…Although many attempts have been made to identify tumour-specific alpha-fetoprotein (AFP) glycoforms or other serological markers for the diagnosis of…”
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Baveno VII criteria identify varices needing treatment in patients with hepatocellular carcinoma of different Barcelona Clinic Liver Cancer stages
Published in Journal of gastroenterology and hepatology (01-08-2023)“…Background Baveno VII criteria for predicting varices needing treatment (VNT) have not been tested in hepatocellular carcinoma (HCC) population. We evaluated…”
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Asian Thoracic Oncology Research Group (ATORG) Expert Consensus Statement on MET Alterations in NSCLC: Diagnostic and Therapeutic Considerations
Published in Clinical lung cancer (01-12-2022)“…•MET alterations are associated with tumorigenesis and TKI resistance in patients with non-small cell lung cancer (NSCLC)•ATORG provides recommendations for…”
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Anti-invasion, anti-proliferation and anoikis-sensitization activities of lapatinib in nasopharyngeal carcinoma cells
Published in Investigational new drugs (01-12-2011)“…Summary Nasopharyngeal cancer (NPC) is a highly prevalent and invasive head and neck cancer in Asia. Disease recurrence and distant metastasis account for…”
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A Comparison of Three Transarterial Lipiodol-Based Formulations for Hepatocellular Carcinoma: In Vivo Biodistribution Study in Humans
Published in Cardiovascular and interventional radiology (01-03-2008)“…This study aimed to evaluate and compare the biodistribution properties of three transarterial Lipiodol-based therapeutic regimens in human hepatocellular…”
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Hepatitis Flare During Immunotherapy in Patients With Current or Past Hepatitis B Virus Infection
Published in The American journal of gastroenterology (28-01-2021)Get full text
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A Randomized Phase 2 Study Comparing the Combination of Ficlatuzumab and Gefitinib with Gefitinib Alone in Asian Patients with Advanced Stage Pulmonary Adenocarcinoma
Published in Journal of thoracic oncology (01-10-2016)“…A randomized phase 2 study was designed to compare the combination of ficlatuzumab (AV-299), a humanized hepatocyte growth factor-neutralizing monoclonal…”
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Upregulation of Bcl2 in NSCLC with acquired resistance to EGFR-TKI
Published in Oncology letters (01-01-2018)“…Lung cancer has the highest incidence and mortality rate worldwide among all malignancy-associated mortalities, of which non-small cell lung cancer accounts…”
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Abstract 2558: The mechanistic study on the effect of platinum-based chemotherapy efficacy imposed by EGFR-TKI regulated ERCC1 in non-small cell lung cancer (NSCLC)
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Abstract Platinum-based chemotherapy is conventionally the first line treatment for EGFR wild type patients while EGFR-TKI is the standard for patients with…”
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Journal Article -
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Multi-drug cancer chemotherapy scheduling by a new memetic optimization algorithm
Published in 2005 IEEE Congress on Evolutionary Computation (2005)“…This paper proposes a new memetic algorithm (MA) to solve the multi-drug chemotherapy optimization problem. The new MA combines GA with a local search…”
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Conference Proceeding