Search Results - "MOHYELDIN, Ahmed"

Chordoma: current concepts, management, and future directions by Walcott, Brian P, Dr, Nahed, Brian V, MD, Mohyeldin, Ahmed, MD, Coumans, Jean-Valery, MD, Kahle, Kristopher T, MD, Ferreira, Manuel J, MD

“…Summary Chordoma is a rare bone cancer that is aggressive, locally invasive, and has a poor prognosis. Chordomas are thought to arise from transformed remnants…”
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FOXD1-ALDH1A3 Signaling Is a Determinant for the Self-Renewal and Tumorigenicity of Mesenchymal Glioma Stem Cells by Cheng, Peng, Wang, Jia, Waghmare, Indrayani, Sartini, Stefania, Coviello, Vito, Zhang, Zhuo, Kim, Sung-Hak, Mohyeldin, Ahmed, Pavlyukov, Marat S, Minata, Mutsuko, Valentim, Claudia L L, Chhipa, Rishi Raj, Bhat, Krishna P L, Dasgupta, Biplab, La Motta, Concettina, Kango-Singh, Madhuri, Nakano, Ichiro

“…Glioma stem-like cells (GSC) with tumor-initiating activity orchestrate the cellular hierarchy in glioblastoma and engender therapeutic resistance. Recent work…”
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Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation by Minata, Mutsuko, Audia, Alessandra, Shi, Junfeng, Lu, Songjian, Bernstock, Joshua, Pavlyukov, Marat S., Das, Arvid, Kim, Sung-Hak, Shin, Yong Jae, Lee, Yeri, Koo, Harim, Snigdha, Kirti, Waghmare, Indrayani, Guo, Xing, Mohyeldin, Ahmed, Gallego-Perez, Daniel, Wang, Jia, Chen, Dongquan, Cheng, Peng, Mukheef, Farah, Contreras, Minerva, Reyes, Joel F., Vaillant, Brian, Sulman, Erik P., Cheng, Shi-Yuan, Markert, James M., Tannous, Bakhos A., Lu, Xinghua, Kango-Singh, Madhuri, Lee, L. James, Nam, Do-Hyun, Nakano, Ichiro, Bhat, Krishna P.

“…Unresectable glioblastoma (GBM) cells in the invading tumor edge can act as seeds for recurrence. The molecular and phenotypic properties of these cells remain…”
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Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2 by Wang, Jia, Cheng, Peng, Pavlyukov, Marat S, Yu, Hai, Zhang, Zhuo, Kim, Sung-Hak, Minata, Mutsuko, Mohyeldin, Ahmed, Xie, Wanfu, Chen, Dongquan, Goidts, Violaine, Frett, Brendan, Hu, Wenhao, Li, Hongyu, Shin, Yong Jae, Lee, Yeri, Nam, Do-Hyun, Kornblum, Harley I, Wang, Maode, Nakano, Ichiro

“…Accumulating evidence suggests that glioma stem cells (GSCs) are important therapeutic targets in glioblastoma (GBM). In this study, we identified NIMA-related…”
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Prospective intraoperative and histologic evaluation of cavernous sinus medial wall invasion by pituitary adenomas and its implications for acromegaly remission outcomes by Mohyeldin, Ahmed, Katznelson, Laurence J., Hoffman, Andrew R., Asmaro, Karam, Ahmadian, Saman S., Eltobgy, Mostafa M., Nayak, Jayakar V., Patel, Zara M., Hwang, Peter H., Fernandez-Miranda, Juan C.

“…Recurrence and biochemical remission rates vary widely among different histological subtypes of pituitary adenoma. In this prospective study, we evaluated 107…”
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Real-time magnetic resonance imaging-guided frameless stereotactic brain biopsy: technical note by Mohyeldin, Ahmed, Lonser, Russell R, Elder, J Bradley

“…The object of this study was to assess the feasibility, accuracy, and safety of real-time MRI-compatible frameless stereotactic brain biopsy. Clinical,…”
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Pyruvate Dehydrogenase Complex Activity Controls Metabolic and Malignant Phenotype in Cancer Cells by McFate, Thomas, Mohyeldin, Ahmed, Lu, Huasheng, Thakar, Jay, Henriques, Jeremy, Halim, Nader D., Wu, Hong, Schell, Michael J., Tsang, Tsz Mon, Teahan, Orla, Zhou, Shaoyu, Califano, Joseph A., Jeoung, Nam Ho, Harris, Robert A., Verma, Ajay

“…High lactate generation and low glucose oxidation, despite normal oxygen conditions, are commonly seen in cancer cells and tumors. Historically known as the…”
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Brachyury-YAP Regulatory Axis Drives Stemness and Growth in Cancer by Shah, Sagar R., David, Justin M., Tippens, Nathaniel D., Mohyeldin, Ahmed, Martinez-Gutierrez, Juan C., Ganaha, Sara, Schiapparelli, Paula, Hamilton, Duane H., Palena, Claudia, Levchenko, Andre, Quiñones-Hinojosa, Alfredo

“…Molecular factors that define stem cell identity have recently emerged as oncogenic drivers. For instance, brachyury, a key developmental transcriptional…”
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Sinonasal morbidity following endoscopic endonasal skull base surgery by Awad, Ahmed J, Mohyeldin, Ahmed, El-Sayed, Ivan H, Aghi, Manish K

“…Highlights • A systematic review of sinonasal morbidity following EESBS. • The most common sinonasal symptoms are crusting, discharge and airflow blockage. •…”
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Reversible Inactivation of HIF-1 Prolyl Hydroxylases Allows Cell Metabolism to Control Basal HIF-1 by Lu, Huasheng, Dalgard, Clifton L., Mohyeldin, Ahmed, McFate, Thomas, Tait, A. Sasha, Verma, Ajay

“…Continuous hydroxylation of the HIF-1 transcription factor α subunit by oxygen and 2-oxoglutarate-dependent dioxygenases promotes decay of this protein and…”
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MELK—a conserved kinase: functions, signaling, cancer, and controversy by Ganguly, Ranjit, Mohyeldin, Ahmed, Thiel, Jordyn, Kornblum, Harley I, Beullens, Monique, Nakano, Ichiro

“…Maternal embryonic leucine zipper kinase (MELK) is a highly conserved serine/threonine kinase initially found to be expressed in a wide range of early…”
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Knowledge and Awareness Regarding Osteoarthritis and Its Factors in Hail Region, Saudi Arabia by Alahmed, Shog K, Mohyeldin, Ahmed M, Alshammari, Areeb, Alshammari, Ziyad F, Alhamdi, Ruba A, Alghaslan, Sulaiman A, Alshammari, Hamad F, Alshamry, Fahad F, Alshammari, Ashwaq H, Alhamdi, Muath S

“…Objectives Osteoarthritis (OA) is a common chronic degenerative joint disease linked to age, joint overuse abnormalities, and previous trauma. This research…”
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Primary central nervous system amyloidoma involving cranial nerves V and VII: A case report and literature review by Son, Esther Yesde, Mohyeldin, Ahmed, Men, Clara, Pendharkar, Arjun, Fernandez-Miranda, Juan C., Kossler, Andrea L.

“…•Amyloidoma is a mass lesion form by amyloid proteins.•Meckel’s cave amyloidomas rarely involve cranial nerves other than CN V.•We present a patient with…”
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Hypoxia-Inducible Erythropoietin Signaling in Squamous Dysplasia and Squamous Cell Carcinoma of the Uterine Cervix and Its Potential Role in Cervical Carcinogenesis and Tumor Progression by Acs, Geza, Zhang, Paul J., McGrath, Cindy M., Acs, Peter, McBroom, John, Mohyeldin, Ahmed, Liu, Suzhen, Lu, Huasheng, Verma, Ajay

“…Tissue hypoxia is a characteristic property of cervical cancers that makes tumors resistant to chemo- and radiation therapy. Erythropoietin (Epo) is a…”
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Mesenchymal stem cells: new approaches for the treatment of neurological diseases by Momin, Eric N, Mohyeldin, Ahmed, Zaidi, Hasan A, Vela, Guillermo, Quiñones-Hinojosa, Alfredo

“…Cellular therapies represent a new frontier in the treatment of neurological disease. Mesenchymal stem cells (MSCs), which can be harvested from bone marrow,…”
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Endogenous 2-oxoacids differentially regulate expression of oxygen sensors by Dalgard, Clifton Lee, Lu, Huasheng, Mohyeldin, Ahmed, Verma, Ajay

“…Adaptations to change in oxygen availability are crucial for survival of multi-cellular organisms and are also implicated in several disease states. Such…”
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Multi-compartment skull base orbital cavernous venous malformation: A rare presentation of a common orbital mass by Azad, Amee D., Sears, Connie M., Hwang, Peter H., Mohyeldin, Ahmed, Fernandez-Miranda, Juan, Kossler, Andrea L.

“…We present a unique case of an orbital intraconal cavernous venous malformation that extended along the trigeminal nerve to the pterygopalatine and middle…”
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Erythropoietin Signaling Promotes Invasiveness of Human Head and Neck Squamous Cell Carcinoma by Mohyeldin, Ahmed, Lu, Huasheng, Dalgard, Clifton, Lai, Stephen Y., Cohen, Noam, Acs, Geza, Verma, Ajay

“…Erythropoietin (Epo) is used for managing anemia in cancer patients. However, recent studies have raised concerns for this practice. We investigated the…”
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Nuances in the Treatment of Malignant Tumors of the Clival and Petroclival Region by Mohyeldin, Ahmed, Prevedello, Daniel M., Jamshidi, Ali O., Filho, Leo F.S. Ditzel, Carrau, Ricardo L.

“…Abstract Introduction  Malignancies of the clivus and petroclival region are mainly chordomas and chondrosarcomas. Although a spectrum of malignancies may…”
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Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target by Hsu, Wesley, Mohyeldin, Ahmed, Shah, Sagar R, ap Rhys, Colette M, Johnson, Lakesha F, Sedora-Roman, Neda I, Kosztowski, Thomas A, Awad, Ola A, McCarthy, Edward F, Loeb, David M, Wolinsky, Jean-Paul, Gokaslan, Ziya L, Quiñones-Hinojosa, Alfredo

“…Chordoma is a malignant bone neoplasm hypothesized to arise from notochordal remnants along the length of the neuraxis. Recent genomic investigation of…”
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