Search Results - "MOHD, SITI MUNIRAH"
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1
An Improved Nanoemulsion Formulation Containing Kojic Monooleate: Optimization, Characterization and In Vitro Studies
Published in Molecules (Basel, Switzerland) (04-06-2020)“…Tyrosinase inhibitors have become increasingly important targets for hyperpigmentation disease treatment. Kojic monooleate (KMO), synthesized from the…”
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2
Ultrasound-assisted extraction conditions optimisation using response surface methodology from Mitragyna speciosa (Korth.) Havil leaves
Published in Ultrasonics sonochemistry (01-12-2021)“…•RSM is a practical approach to optimize the UAE conditions of M. speciosa leaves and provided further insights into the correlation between the independent…”
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3
Quantitative analysis of selected alkaloids of Mitragyna speciosa using 1H quantitative nuclear magnetic resonance spectroscopy
Published in Magnetic resonance in chemistry (01-11-2024)“…Mitragyna speciosa is a perennial plant native to Asia, well known for its psychoactive properties. Its major alkaloid mitragynine is known to have sedative…”
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4
Comprehensive GCMS and LC-MS/MS Metabolite Profiling of Chlorella vulgaris
Published in Marine drugs (17-07-2020)“…The commercial cultivation of microalgae began in the 1960s and was one of the first target organisms. The species has long been considered a potential source…”
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5
Embryonic mercury exposure in zebrafish: Alteration of metabolites and gene expression, related to visual and behavioral impairments
Published in Ecotoxicology and environmental safety (01-05-2023)“…The widespread presence of mercury, a heavy metal found in the environment and used in numerous industries and domestic, raises concerns about its potential…”
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6
Preliminary Insight of Pyrrolylated-Chalcones as New Anti-Methicillin-Resistant Staphylococcus aureus (Anti-MRSA) Agents
Published in Molecules (Basel, Switzerland) (01-09-2021)“…Bacterial infections are regarded as one of the leading causes of fatal morbidity and death in patients infected with diseases. The ability of microorganisms,…”
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7
Solid-Phase Extraction of Active Compounds from Natural Products by Molecularly Imprinted Polymers: Synthesis and Extraction Parameters
Published in Polymers (31-10-2021)“…Molecularly imprinted polymers (MIPs) are synthetic polymers with a predetermined selectivity for a particular analyte or group of structurally related…”
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8
Zebrafish phenotypic screen identifies novel Notch antagonists
Published in Investigational new drugs (01-04-2017)“…Summary Zebrafish represents a powerful in vivo model for phenotype-based drug discovery to identify clinically relevant small molecules. By utilizing this…”
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Synthesis of quinoxaline derivatives using different solvent systems, their potent antibacterial activities and molecular docking
Published in Results in Chemistry (01-01-2024)“…[Display omitted] •To synthesize 2,3- dichloroquinoxalines derivatives using conventional methods.•To evaluate the antibacterial activities of the synthesized…”
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10
Crystal structure and Hirshfeld surface analysis of 3-(3-hy-droxy-phen-yl)-1-(1 H -pyrrol-2-yl)prop-2-en-1-one hemihydrate
Published in Acta crystallographica. Section E, Crystallographic communications (01-04-2023)“…High-quality single crystals of the title compound, 2C H NO ·H O, were grown and a structural analysis was performed. The asymmetric unit comprises one…”
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Synthesis and biological evaluation of asymmetrical diarylpentanoids as antiinflammatory, anti-α-glucosidase, and antioxidant agents
Published in Medicinal chemistry research (01-11-2019)“…A series of seven new ( 1 , 3 , 6 , 7 , 10 , 12 , and 13 ) and six ( 2 , 4 , 5 , 8 , 9 , and 11 ) known diarylpentanoid analogs were synthesized and assessed…”
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12
Optimizing reaction efficiency: Microwave-supported synthesis of quinoxaline-based compounds
Published in Results in Chemistry (01-01-2024)“…[Display omitted] The chemistry of chloroquinoxalines has garnered significant interest owing to the potential applications of this nitrogen-containing…”
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13
Synthesis and sar study of diarylpentanoid analogues as new anti-inflammatory agents
Published in Molecules (Basel, Switzerland) (09-10-2014)“…A series of ninety-seven diarylpentanoid derivatives were synthesized and evaluated for their anti-inflammatory activity through NO suppression assay using…”
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14
Identification of α-glucosidase inhibitory compounds from Curcuma mangga fractions
Published in International journal of food properties (01-01-2020)“…Curcuma mangga is a medicinal plant, and its rhizomes are often used to treat various conditions, such as fever, thorax pain, itching, stomachaches, skin…”
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15
Mapping Molecular Networks within Clitoria ternatea Linn. against LPS-Induced Neuroinflammation in Microglial Cells, with Molecular Docking and In Vivo Toxicity Assessment in Zebrafish
Published in Pharmaceuticals (Basel, Switzerland) (12-04-2022)“…Clitoria ternatea Linn. (CT), or butterfly pea, is an Ayurvedic plant traditionally used as a brain tonic. Recently, it was reported to be of use in treating…”
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Embryonic Arsenic Exposure Triggers Long-Term Behavioral Impairment with Metabolite Alterations in Zebrafish
Published in Toxics (Basel) (24-08-2022)“…Arsenic trioxide (As O ) is a ubiquitous heavy metal in the environment. Exposure to this toxin at low concentrations is unremarkable in developing organisms…”
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In silico studies, X-ray diffraction analysis and biological investigation of fluorinated pyrrolylated-chalcones in zebrafish epilepsy models
Published in Heliyon (01-02-2023)“…Epilepsy is the third most common known brain disease worldwide. Several antiepileptic drugs (AEDs) are available to improve seizure control. However, the…”
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Preliminary insight on diarylpentanoids as potential antimalarials: In silico, in vitro pLDH and in vivo zebrafish toxicity assessment
Published in Heliyon (15-03-2024)“…Malaria remains a major public health problem worldwide, including in Southeast Asia. Chemotherapeutic agents such as chloroquine (CQ) are effective, but…”
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Metabolomics-Driven Discovery of an Introduced Species and Two Malaysian Piper betle L. Variants
Published in Plants (Basel) (19-11-2021)“…The differences in pungency of “sirih” imply the probable occurrence of several variants of Piper betle L. in Malaysia. However, the metabolite profiles…”
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Exploring quinoxaline derivatives: An overview of a new approach to combat antimicrobial resistance
Published in European journal of medicinal chemistry (05-10-2024)“…Antimicrobial resistance (AMR) has emerged as a long-standing global issue ever since the introduction of penicillin, the first antibiotic. Scientists are…”
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