Search Results - "MOHAPI, Lerato"
-
1
One Month of Rifapentine plus Isoniazid to Prevent HIV-Related Tuberculosis
Published in The New England journal of medicine (14-03-2019)“…Treatment of latent tuberculosis infection is an important control measure, especially in patients coinfected with HIV. In this international phase 3 trial, 1…”
Get full text
Journal Article -
2
Timing of Antiretroviral Therapy for HIV-1 Infection and Tuberculosis
Published in The New England journal of medicine (20-10-2011)“…In this international study involving 809 patients with HIV and TB coinfection, earlier therapy for both infections, versus waiting 8 to 12 weeks to initiate…”
Get full text
Journal Article -
3
Liver toxicity associated with tuberculosis chemotherapy in the REMoxTB study
Published in BMC medicine (28-03-2018)“…Drug-induced liver injury (DILI) is a common complication of tuberculosis treatment. We utilised data from the REMoxTB clinical trial to describe the incidence…”
Get full text
Journal Article -
4
Empirical tuberculosis therapy versus isoniazid in adult outpatients with advanced HIV initiating antiretroviral therapy (REMEMBER): a multicountry open-label randomised controlled trial
Published in The Lancet (British edition) (19-03-2016)“…Summary Background Mortality within the first 6 months after initiating antiretroviral therapy is common in resource-limited settings and is often due to…”
Get full text
Journal Article -
5
Isoniazid preventive therapy, HAART and tuberculosis risk in HIV-infected adults in South Africa : a prospective cohort
Published in AIDS (London) (13-03-2009)“…The World Health Organization recommends isoniazid preventive therapy (IPT) for preventing tuberculosis in HIV-infected adults, although few countries have…”
Get full text
Journal Article -
6
Factors Associated With and Characteristic of HIV/Tuberculosis Co-Infection: A Retrospective Analysis of SECOND-LINE Clinical Trial Participants
Published in Journal of acquired immune deficiency syndromes (1999) (01-05-2021)“…Tuberculosis (TB) is a common infection in people living with HIV. However, the risk factors for HIV/TB co-infection in second-line HIV therapy are poorly…”
Get full text
Journal Article -
7
Adherence to drug-refill is a useful early warning indicator of virologic and immunologic failure among HIV patients on first-line ART in South Africa
Published in PloS one (09-03-2011)“…Affordable strategies to prevent treatment failure on first-line regimens among HIV patients are essential for the long-term success of antiretroviral therapy…”
Get full text
Journal Article -
8
Integrative Multi-Omics Reveals Serum Markers of Tuberculosis in Advanced HIV
Published in Frontiers in immunology (08-06-2021)“…Tuberculosis (TB) accounts for disproportionate morbidity and mortality among persons living with HIV (PLWH). Conventional methods of TB diagnosis, including…”
Get full text
Journal Article -
9
Body mass index and risk of tuberculosis and death
Published in AIDS (London) (19-06-2010)“…High BMI has been shown to be protective against tuberculosis (TB) among HIV-uninfected individuals, as well as against disease progression and mortality among…”
Get full text
Journal Article -
10
CD4 counts and viral loads of newly diagnosed HIV-infected individuals: implications for treatment as prevention
Published in PloS one (04-03-2014)“…To report the viral load and CD4 count in HIV-infected, antiretroviral naïve, first -time HIV-testers, not immediately eligible for treatment initiation by…”
Get full text
Journal Article -
11
Raltegravir non-inferior to nucleoside based regimens in second-line therapy with lopinavir/ritonavir over 96 weeks: a randomised open label study for the treatment of HIV-1 infection
Published in PloS one (27-02-2015)“…To determine the durability over 96 weeks of safety and efficacy of lopinavir/ritonavir (LPV/r) and raltegravir (RAL) which was demonstrated to have…”
Get full text
Journal Article -
12
Progression and regression of premalignant cervical lesions in HIV-infected women from Soweto: a prospective cohort
Published in AIDS (London) (02-01-2011)“…To ascertain progression and regression of cervical dysplasia in HIV-infected women in Soweto. Prospective cohort. Women attending an HIV wellness clinic were…”
Get full text
Journal Article -
13
Nevirapine- versus lopinavir/ritonavir-based initial therapy for HIV-1 infection among women in Africa: a randomized trial
Published in PLoS medicine (01-06-2012)“…Nevirapine (NVP) is widely used in antiretroviral treatment (ART) of HIV-1 globally. The primary objective of the AA5208/OCTANE trial was to compare the…”
Get full text
Journal Article -
14
The effect of a maturing antiretroviral program on early mortality for patients with advanced immune-suppression in Soweto, South Africa
Published in PloS one (28-11-2013)“…We hypothesize that time to initiate care and maturity of a treatment program impact on outcome of severely immuno-compromised patients with higher risk of…”
Get full text
Journal Article -
15
Toxicity related to standard TB therapy for pulmonary tuberculosis and treatment outcomes in the REMoxTB study according to HIV status
Published in BMC pulmonary medicine (14-08-2019)“…The phase III REMoxTB study prospectively enrolled HIV-positive (with CD4+ count > 250 cells, not on anti-retroviral therapy) and HIV-negative patients. We…”
Get full text
Journal Article -
16
-
17
Switching at low HIV-1 RNA into fixed dose combinations : TDF/FTC/RPV is non-inferior to TDF/FTC/ EFV in first-line suppressed patients living with HIV
Published in Southern African journal of HIV medicine (2019)“…Background: In low- and middle-income countries (LMICs), a substantial unmet need for affordable single-tablet regimen (STR) options remains. Rilpivirine (RPV,…”
Get full text
Journal Article -
18
Body composition and metabolic outcomes after 96 weeks of treatment with ritonavir-boosted lopinavir plus either nucleoside or nucleotide reverse transcriptase inhibitors or raltegravir in patients with HIV with virological failure of a standard first-line antiretroviral therapy regimen: a substudy of the randomised, open-label, non-inferiority SECOND-LINE study
Published in The lancet HIV (01-01-2017)“…Summary Background Lipoatrophy is one of the most feared complications associated with the use of nucleoside or nucleotide reverse transcriptase inhibitors…”
Get full text
Journal Article -
19
STRETCHing delivery of HIV health services
Published in The Lancet (British edition) (08-09-2012)“…In The Lancet, Lara Fairall and colleagues7 present a cluster-randomised trial done in the Free State province of South Africa that tested task shifting of ART…”
Get full text
Journal Article -
20
Using a domain specific language for SDR to facilitate radar signal processing in heterogeneous computing architectures
Published in 2015 IEEE Radar Conference (01-10-2015)“…This paper presents the use of a Domain-Specific Language (DSL) for Software Defined Radio (SDR) in a Radar digital signal processing (DSP) using heterogeneous…”
Get full text
Conference Proceeding