Search Results - "MOERTEL, C. G"

Prospectively randomized trial of postoperative adjuvant chemotherapy in patients with high-risk colon cancer by O'Connell, M J, Laurie, J A, Kahn, M, Fitzgibbons, Jr, R J, Erlichman, C, Shepherd, L, Moertel, C G, Kocha, W I, Pazdur, R, Wieand, H S, Rubin, J, Vukov, A M, Donohue, J H, Krook, J E, Figueredo, A

“…This study had two major goals: (1) to assess the effectiveness of a regimen of fluorouracil (5-FU) plus levamisole plus leucovorin as postoperative surgical…”
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Intergroup study of fluorouracil plus levamisole as adjuvant therapy for stage II/Dukes' B2 colon cancer by Moertel, C G, Fleming, T R, Macdonald, J S, Haller, D G, Laurie, J A, Tangen, C M, Ungerleider, J S, Emerson, W A, Tormey, D C, Glick, J H

“…To determine the effectiveness of fluorouracil plus levamisole administered postoperatively to patients with resected stage II (Dukes' B2) colon cancer. This…”
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Streptozocin–Doxorubicin, Streptozocin–Fluorouracil, or Chlorozotocin in the Treatment of Advanced Islet-Cell Carcinoma by Moertel, Charles G, Lefkopoulo, Myrto, Lipsitz, Stuart, Hahn, Richard G, Klaassen, David

“…ADVANCED carcinoma of the islet cells of the pancreas, although rare, presents a kaleidoscope of clinical challenges. In addition to the usual problems…”
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Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma by Poon, M A, O'Connell, M J, Moertel, C G, Wieand, H S, Cullinan, S A, Everson, L K, Krook, J E, Mailliard, J A, Laurie, J A, Tschetter, L K

“…The purpose of this study was to evaluate the effectiveness of several new approaches designed to enhance the activity of fluorouracil (5-FU) in the management…”
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Effective Surgical Adjuvant Therapy for High-Risk Rectal Carcinoma by Krook, James E, Moertel, Charles G, Gunderson, Leonard L, Wieand, Harry S, Collins, Roger T, Beart, Robert W, Kubista, Theodore P, Poon, Michael A, Meyers, William C, Mailliard, James A, Twito, Donald I, Morton, Roscoe F, Veeder, Michael H, Witzig, Thomas E, Cha, Stephen, Vidyarthi, Subhash C

“…CARCINOMA of the rectum is one of the more common malignant diseases in this country, estimated to afflict some 45,500 persons during 1991. 1 It has certainly…”
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Granulocyte Colony-Stimulating Factor in Severe Chemotherapy-Induced Afebrile Neutropenia by Hartmann, Lynn C, Tschetter, Loren K, Habermann, Thomas M, Ebbert, Larry P, Johnson, P. Steven, Mailliard, James A, Levitt, Ralph, Suman, Vera J, Witzig, Thomas E, Wieand, H.S, Miller, Langdon L, Moertel, Charles G, Grendahl, Darryl C, Herrera, Dianne M

“…Neutropenia and resultant infection are potentially life-threatening side effects of cancer chemotherapy. The use of dose-intensive chemotherapeutic regimens…”
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The management of patients with advanced carcinoid tumors and islet cell carcinomas by MOERTEL, C. G, JOHNSON, C. M, MCKUSICK, M. A, MARTIN, J. K, NAGORNEY, D. M, KVOLS, L. K, RUBIN, J, KUNSELMAN, S

“…To determine the effectiveness of hepatic artery occlusion alone and with sequenced chemotherapy for patients with hepatic-dominant metastases of islet cell…”
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Hepatic toxicity associated with fluorouracil plus levamisole adjuvant therapy by Moertel, C G, Fleming, T R, Macdonald, J S, Haller, D G, Laurie, J A

“…To determine the frequency and nature of hepatic toxicity associated with fluorouracil (5-FU) plus levamisole adjuvant therapy. All patients had resection of…”
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Incidence and morbidity of cholelithiasis in patients receiving chronic octreotide for metastatic carcinoid and malignant islet cell tumors by Trendle, Michael C., Moertel, Charles G., Kvols, Larry K.

“…BACKGROUND Octreotide, a long‐acting somatostatin analogue, has demonstrated clinical utility in patients with carcinoid syndrome and malignant islet cell…”
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Therapy of metastatic carcinoid tumor and the malignant carcinoid syndrome with recombinant leukocyte A interferon by Moertel, C G, Rubin, J, Kvols, L K

“…Twenty-seven patients with metastatic carcinoid tumor, 24 of whom had the malignant carcinoid syndrome, were treated with recombinant leukocyte A interferon at…”
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Cytoreductive hepatic surgery for neuroendocrine tumors by McEntee, G P, Nagorney, D M, Kvols, L K, Moertel, C G, Grant, C S

“…We retrospectively reviewed 37 patients who underwent hepatic resection between 1970 and 1989 to evaluate the role of cytoreductive hepatic surgery in patients…”
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Treatment of the carcinoid tumor and the malignant carcinoid syndrome by Moertel, C G

“…Certainly in treatment of the carcinoid tumor surgery has a well-established curative and palliative potential. The primary challenge is a knowledgable…”
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Perioperative blood transfusions do not affect disease recurrence of patients undergoing curative resection of colorectal carcinoma: a Mayo/North Central Cancer Treatment Group study by Donohue, J H, Williams, S, Cha, S, Windschitl, H E, Witzig, T E, Nelson, H, Fitzgibbons, Jr, R J, Wieand, H S, Moertel, C G

“…To evaluate the effect of perioperative blood transfusions on colorectal cancer recurrence and patient survival. A total of 1,051 patients treated with…”
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Treatment of locally unresectable cancer of the stomach and pancreas: a randomized comparison of 5-fluorouracil alone with radiation plus concurrent and maintenance 5-fluorouracil--an Eastern Cooperative Oncology Group study by Klaassen, D J, MacIntyre, J M, Catton, G E, Engstrom, P F, Moertel, C G

“…One hundred ninety-one patients with pathologically confirmed, locally unresectable adenocarcinoma of the stomach (57 patients) and pancreas (91 patients),…”
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Treatment of the malignant carcinoid syndrome. Evaluation of a long-acting somatostatin analogue by Kvols, L K, Moertel, C G, O'Connell, M J, Schutt, A J, Rubin, J, Hahn, R G

“…We studied the effects of a long-acting analogue of somatostatin (SMS 201-995, Sandoz) in 25 patients with histologically proved metastatic carcinoid tumors…”
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Chemotherapy for Colorectal Cancer by Moertel, Charles G

“…Carcinoma of the large bowel, which will afflict over 150,000 Americans this year, is second only to lung cancer as a cause of death from cancer 1 . Although…”
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Prospectively randomized North Central Cancer Treatment Group trial of intensive-course fluorouracil combined with the l-isomer of intravenous leucovorin, oral leucovorin, or intravenous leucovorin for the treatment of advanced colorectal cancer by Goldberg, R M, Hatfield, A K, Kahn, M, Sargent, D J, Knost, J A, O'Connell, M J, Krook, J E, Maillard, J A, Wiesenfeld, M, Schaefer, P L, Tirona, M T, Moertel, C G

“…A three-arm randomized phase III trial in advanced colorectal cancer patients was designed to test whether substitution of an equivalent dose of (1)…”
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The physician's responsibility toward hopelessly ill patients. A second look by Wanzer, S H, Federman, D D, Adelstein, S J, Cassel, C K, Cassem, E H, Cranford, R E, Hook, E W, Lo, B, Moertel, C G, Safar, P

“…Physicians have a specific responsibility toward patients who are hopelessly ill, dying, or in the end stages of an incurable disease. In a summary of current…”
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Treatment of metastatic islet cell carcinoma with a somatostatin analogue (SMS 201-995) by Kvols, L K, Buck, M, Moertel, C G, Schutt, A J, Rubin, J, O'Connell, M J, Hahn, R G

“…We used an octapeptide analogue of somatostatin, SMS 201-995, in dosages ranging from 150 to 450 micrograms/d administered subcutaneously in three daily doses…”
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Carcinoid tumor of the appendix: treatment and prognosis by Moertel, C G, Weiland, L H, Nagorney, D M, Dockerty, M B

“…In a long-term study of 150 unselected patients with carcinoid tumors of the appendix, we found that the neoplasms were usually less than 1.0 cm in largest…”
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