Search Results - "MOEN VOLLAN, Hans Kristian"

JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer by Yamamoto, Shoji, Wu, Zhenhua, Russnes, Hege G., Takagi, Shinji, Peluffo, Guillermo, Vaske, Charles, Zhao, Xi, Moen Vollan, Hans Kristian, Maruyama, Reo, Ekram, Muhammad B., Sun, Hanfei, Kim, Jee Hyun, Carver, Kristopher, Zucca, Mattia, Feng, Jianxing, Almendro, Vanessa, Bessarabova, Marina, Rueda, Oscar M., Nikolsky, Yuri, Caldas, Carlos, Liu, X. Shirley, Polyak, Kornelia

“…Recurrent mutations in histone-modifying enzymes imply key roles in tumorigenesis, yet their functional relevance is largely unknown. Here, we show that…”
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Copynumber: Efficient algorithms for single- and multi-track copy number segmentation by Nilsen, Gro, Liestøl, Knut, Van Loo, Peter, Moen Vollan, Hans Kristian, Eide, Marianne B, Rueda, Oscar M, Chin, Suet-Feung, Russell, Roslin, Baumbusch, Lars O, Caldas, Carlos, Børresen-Dale, Anne-Lise, Lingjaerde, Ole Christian

“…Cancer progression is associated with genomic instability and an accumulation of gains and losses of DNA. The growing variety of tools for measuring genomic…”
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TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance by SILWAL-PANDIT, Laxmi, MOEN VOLLAN, Hans Kristian, CALDAS, Carlos, LANGERØD, Anita, CHIN, Suet-Feung, RUEDA, Oscar M, MCKINNEY, Steven, OSAKO, Tomo, QUIGLEY, David A, KRISTENSEN, Vessela N, APARICIO, Samuel, BØRRESEN-DALE, Anne-Lise

“…In breast cancer, the TP53 gene is frequently mutated and the mutations have been associated with poor prognosis. The prognostic impact of the different types…”
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The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells by Sahlberg, Kristine Kleivi, Hongisto, Vesa, Edgren, Henrik, Mäkelä, Rami, Hellström, Kirsi, Due, Eldri U., Moen Vollan, Hans Kristian, Sahlberg, Niko, Wolf, Maija, Børresen-Dale, Anne-Lise, Perälä, Merja, Kallioniemi, Olli

“…About 20% of breast cancers are characterized by amplification and overexpression of the HER2 oncogene. Although significant progress has been achieved for…”
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The Sub-Cellular Localization of WRAP53 Has Prognostic Impact in Breast Cancer by Silwal-Pandit, Laxmi, Russnes, Hege, Borgen, Elin, Skarpeteig, Veronica, Moen Vollan, Hans Kristian, Schlichting, Ellen, Kåresen, Rolf, Naume, Bjørn, Børresen-Dale, Anne-Lise, Farnebo, Marianne, Langerød, Anita

“…WRAP53 protein controls intracellular trafficking of DNA repair proteins, the telomerase enzyme, and splicing factors. Functional loss of the protein has been…”
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The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors by Quigley, David A., Fiorito, Elisa, Nord, Silje, Van Loo, Peter, Alnæs, Grethe Grenaker, Fleischer, Thomas, Tost, Jorg, Moen Vollan, Hans Kristian, Tramm, Trine, Overgaard, Jens, Bukholm, Ida R., Hurtado, Antoni, Balmain, Allan, Børresen-Dale, Anne-Lise, Kristensen, Vessela

“…Genome-wide association studies have identified numerous loci linked to breast cancer susceptibility, but the mechanism by which variations at these loci…”
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The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes by Pereira, Bernard, Chin, Suet-Feung, Rueda, Oscar M, Vollan, Hans-Kristian Moen, Provenzano, Elena, Bardwell, Helen A, Pugh, Michelle, Jones, Linda, Russell, Roslin, Sammut, Stephen-John, Tsui, Dana W Y, Liu, Bin, Dawson, Sarah-Jane, Abraham, Jean, Northen, Helen, Peden, John F, Mukherjee, Abhik, Turashvili, Gulisa, Green, Andrew R, McKinney, Steve, Oloumi, Arusha, Shah, Sohrab, Rosenfeld, Nitzan, Murphy, Leigh, Bentley, David R, Ellis, Ian O, Purushotham, Arnie, Pinder, Sarah E, Børresen-Dale, Anne-Lise, Earl, Helena M, Pharoah, Paul D, Ross, Mark T, Aparicio, Samuel, Caldas, Carlos

“…The genomic landscape of breast cancer is complex, and inter- and intra-tumour heterogeneity are important challenges in treating the disease. In this study,…”
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Triple-Negative Breast Cancer and the Need for New Therapeutic Targets by Engebraaten, Olav, Vollan, Hans Kristian Moen, Børresen-Dale, Anne-Lise

“…Triple-negative breast cancers (TNBCs) are a diverse and heterogeneous group of tumors that by definition lack estrogen and progesterone receptors and…”
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Increased coagulation activity and genetic polymorphisms in the F5, F10 and EPCR genes are associated with breast cancer: a case-control study by Tinholt, Mari, Viken, Marte Kathrine, Dahm, Anders Erik, Vollan, Hans Kristian Moen, Sahlberg, Kristine Kleivi, Garred, Oystein, Børresen-Dale, Anne-Lise, Jacobsen, Anne Flem, Kristensen, Vessela, Bukholm, Ida, Kåresen, Rolf, Schlichting, Ellen, Skretting, Grethe, Lie, Benedicte Alexandra, Sandset, Per Morten, Iversen, Nina

“…The procoagulant state in cancer increases the thrombotic risk, but also supports tumor progression. To investigate the molecular mechanisms controlling cancer…”
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Copy number variations alter methylation and parallel IGF2 overexpression in adrenal tumors by Nielsen, Helene Myrtue, How-Kit, Alexandre, Guerin, Carole, Castinetti, Frederic, Vollan, Hans Kristian Moen, De Micco, Catherine, Daunay, Antoine, Taieb, David, Van Loo, Peter, Besse, Celine, Kristensen, Vessela N, Hansen, Lise Lotte, Barlier, Anne, Sebag, Frederic, Tost, Jörg

“…Overexpression of insulin growth factor 2 (IGF2) is a hallmark of adrenocortical carcinomas and pheochromocytomas. Previous studies investigating the IGF2/H19…”
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Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations by Höglander, Elen Kristine, Nord, Silje, Wedge, David C, Lingjærde, Ole Christian, Silwal-Pandit, Laxmi, Gythfeldt, Hedda vdL, Vollan, Hans Kristian Moen, Fleischer, Thomas, Krohn, Marit, Schlitchting, Ellen, Borgen, Elin, Garred, Øystein, Holmen, Marit M, Wist, Erik, Naume, Bjørn, Van Loo, Peter, Børresen-Dale, Anne-Lise, Engebraaten, Olav, Kristensen, Vessela

“…Chemotherapeutic agents such as anthracyclines and taxanes are commonly used in the neoadjuvant setting. Bevacizumab is an antibody which binds to vascular…”
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Integrative Functional Genomics Analysis of Sustained Polyploidy Phenotypes in Breast Cancer Cells Identifies an Oncogenic Profile for GINS2 by Rantala, Juha K., Edgren, Henrik, Lehtinen, Laura, Wolf, Maija, Kleivi, Kristine, Vollan, Hans Kristian Moen, Aaltola, Anna-Riina, Laasola, Petra, Kilpinen, Sami, Saviranta, Petri, Iljin, Kristiina, Kallioniemi, Olli

“…Aneuploidy is among the most obvious differences between normal and cancer cells. However, mechanisms contributing to development and maintenance of aneuploid…”
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Erratum: The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes by Pereira, Bernard, Chin, Suet-Feung, Rueda, Oscar M., Vollan, Hans-Kristian Moen, Provenzano, Elena, Bardwell, Helen A., Pugh, Michelle, Jones, Linda, Russell, Roslin, Sammut, Stephen-John, Tsui, Dana W. Y., Liu, Bin, Dawson, Sarah-Jane, Abraham, Jean, Northen, Helen, Peden, John F., Mukherjee, Abhik, Turashvili, Gulisa, Green, Andrew R., McKinney, Steve, Oloumi, Arusha, Shah, Sohrab, Rosenfeld, Nitzan, Murphy, Leigh, Bentley, David R., Ellis, Ian O., Purushotham, Arnie, Pinder, Sarah E., Børresen-Dale, Anne-Lise, Earl, Helena M., Pharoah, Paul D., Ross, Mark T., Aparicio, Samuel, Caldas, Carlos

“…Nature Communications 7 Article number:11479 (2016); Published: 10 May 2016; Updated: 6 June 2016. The original version of this Article contained an error in…”
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The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes by Pereira, Bernard, Chin, Suet-Feung, Rueda, Oscar M., Vollan, Hans-Kristian Moen, Provenzano, Elena, Bardwell, Helen A., Pugh, Michelle, Jones, Linda, Russell, Roslin, Sammut, Stephen-John, Tsui, Dana W. Y., Liu, Bin, Dawson, Sarah-Jane, Abraham, Jean, Northen, Helen, Peden, John F., Mukherjee, Abhik, Turashvili, Gulisa, Green, Andrew R., McKinney, Steve, Oloumi, Arusha, Shah, Sohrab, Rosenfeld, Nitzan, Murphy, Leigh, Bentley, David R., Ellis, Ian O., Purushotham, Arnie, Pinder, Sarah E., Børresen-Dale, Anne-Lise, Earl, Helena M., Pharoah, Paul D., Ross, Mark T., Aparicio, Samuel, Caldas, Carlos

“…The genomic landscape of breast cancer is complex, and inter- and intra-tumour heterogeneity are important challenges in treating the disease. In this study,…”
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Ischemia caused by time to freezing induces systematic microRNA and mRNA responses in cancer tissue by Borgan, Eldrid, Navon, Roy, Vollan, Hans Kristian Moen, Schlichting, Ellen, Sauer, Torill, Yakhini, Zohar, Lingjærde, Ole Christian, Sørlie, Therese, Børresen-Dale, Anne-Lise

“…Time to freezing tumor tissue for RNA expression analysis will always vary to some extent. To evaluate the effect of ischemia time, tumor tissue from ten…”
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Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status by Zhao, Xi, Rødland, Einar Andreas, Sørlie, Therese, Vollan, Hans Kristian Moen, Russnes, Hege G, Kristensen, Vessela N, Lingjærde, Ole Christian, Børresen-Dale, Anne-Lise

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Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors by Cheng, Jiqiu, Demeulemeester, Jonas, Wedge, David C., Vollan, Hans Kristian M., Pitt, Jason J., Russnes, Hege G., Pandey, Bina P., Nilsen, Gro, Nord, Silje, Bignell, Graham R., White, Kevin P., Børresen-Dale, Anne-Lise, Campbell, Peter J., Kristensen, Vessela N., Stratton, Michael R., Lingjærde, Ole Christian, Moreau, Yves, Van Loo, Peter

“…Homozygous deletions are rare in cancers and often target tumour suppressor genes. Here, we build a compendium of 2218 primary tumours across 12 human cancer…”
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Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome by Aure, Miriam Ragle, Vitelli, Valeria, Jernström, Sandra, Kumar, Surendra, Krohn, Marit, Due, Eldri U, Haukaas, Tonje Husby, Leivonen, Suvi-Katri, Vollan, Hans Kristian Moen, Lüders, Torben, Rødland, Einar, Vaske, Charles J, Zhao, Wei, Møller, Elen K, Nord, Silje, Giskeødegård, Guro F, Bathen, Tone Frost, Caldas, Carlos, Tramm, Trine, Alsner, Jan, Overgaard, Jens, Geisler, Jürgen, Bukholm, Ida R K, Naume, Bjørn, Schlichting, Ellen, Sauer, Torill, Mills, Gordon B, Kåresen, Rolf, Mælandsmo, Gunhild M, Lingjærde, Ole Christian, Frigessi, Arnoldo, Kristensen, Vessela N, Børresen-Dale, Anne-Lise, Sahlberg, Kristine K

“…Breast cancer is a heterogeneous disease at the clinical and molecular level. In this study we integrate classifications extracted from five different…”
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Lymphocyte Invasion in IC10/Basal-Like Breast Tumors Is Associated with Wild-Type TP53 by Quigley, David, Silwal-Pandit, Laxmi, Dannenfelser, Ruth, Langerød, Anita, Vollan, Hans Kristian Moen, Vaske, Charles, Siegel, Josie Ursini, Troyanskaya, Olga, Chin, Suet-Feung, Caldas, Carlos, Balmain, Allan, Børresen-Dale, Anne-Lise, Kristensen, Vessela

“…Lymphocytic infiltration is associated with better prognosis in several epithelial malignancies including breast cancer. The tumor suppressor TP53 is mutated…”
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Data-driven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression, ER activity, and genomic complexity by Dannenfelser, Ruth, Nome, Marianne, Tahiri, Andliena, Ursini-Siegel, Josie, Vollan, Hans Kristian Moen, Haakensen, Vilde D, Helland, Åslaug, Naume, Bjørn, Caldas, Carlos, Børresen-Dale, Anne-Lise, Kristensen, Vessela N, Troyanskaya, Olga G

“…The tumor microenvironment is now widely recognized for its role in tumor progression, treatment response, and clinical outcome. The intratumoral immunological…”
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