Search Results - "MODDES, Lauren"

RasGRP1 stimulation enhances ubiquitination and endocytosis of the sodium-chloride cotransporter by Ko, Benjamin, Kamsteeg, Erik-Jan, Cooke, Leslie L, Moddes, Lauren N, Deen, Peter M T, Hoover, Robert S

“…The sodium-chloride cotransporter (NCC) is the principal salt-absorptive pathway in the distal convoluted tubule. Recently, we described a novel pathway of NCC…”
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Nedd4-2 Modulates Renal Na+-Cl― Cotransporter via the Aldosterone-SGK1-Nedd4-2 Pathway by PABLO ARROYO, Juan, LAGNAZ, Dagmara, STOKES, John B, HOOVER, Robert S, GAMBA, Gerardo, STAUB, Olivier, RONZAUD, Caroline, VAZQUEZ, Norma, KO, Benjamin S, MODDES, Lauren, RUFFIEUX-DAIDIE, Dorothée, HAUSEL, Pierrette, KOESTERS, Robert, YANG, Baoli

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Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway by Arroyo, Juan Pablo, Lagnaz, Dagmara, Ronzaud, Caroline, Vázquez, Norma, Ko, Benjamin S, Moddes, Lauren, Ruffieux-Daidié, Dorothée, Hausel, Pierrette, Koesters, Robert, Yang, Baoli, Stokes, John B, Hoover, Robert S, Gamba, Gerardo, Staub, Olivier

“…Regulation of renal Na(+) transport is essential for controlling blood pressure, as well as Na(+) and K(+) homeostasis. Aldosterone stimulates Na(+)…”
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Acute aldosterone treatment enhances SPAK and NCC phosphorylation by Ko, Benjamin, Moddes, Lauren, Hoover, Robert S

“…In animal studies, aldosterone (aldo) increases sodium chloride cotransporter (NCC) function and total abundance at 3–5 days. Recent work shows that NCC and…”
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Mechanisms of Aldosterone Action on NCC by Ko, Benjamin, Moddes, Lauren, Cooke, Leslie, Hoover, Robert S

“…Aldosterone increases NCC function and protein expression in whole animal studies at 72 hours but more acute effects of aldosterone on NCC activity have not…”
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