Search Results - "MOBLEY, Harry L. T"

Pathogenesis of Gram-Negative Bacteremia by Holmes, Caitlyn L, Anderson, Mark T, Mobley, Harry L T, Bachman, Michael A

“…Gram-negative bacteremia is a devastating public health threat, with high mortality in vulnerable populations and significant costs to the global economy…”
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A systematic analysis of hypermucoviscosity and capsule reveals distinct and overlapping genes that impact Klebsiella pneumoniae fitness by Mike, Laura A, Stark, Andrew J, Forsyth, Valerie S, Vornhagen, Jay, Smith, Sara N, Bachman, Michael A, Mobley, Harry L T

“…Hypervirulent K. pneumoniae (hvKp) is a distinct pathotype that causes invasive community-acquired infections in healthy individuals. Hypermucoviscosity (hmv)…”
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TnseqDiff: identification of conditionally essential genes in transposon sequencing studies by Zhao, Lili, Anderson, Mark T, Wu, Weisheng, T Mobley, Harry L, Bachman, Michael A

“…Tn-Seq is a high throughput technique for analysis of transposon mutant libraries to determine conditional essentiality of a gene under an experimental…”
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Redundancy and Specificity of Escherichia coli Iron Acquisition Systems during Urinary Tract Infection by Garcia, Erin C, Brumbaugh, Ariel R, Mobley, Harry L.T

“…Uropathogenic Escherichia coli (UPEC), the predominant cause of uncomplicated urinary tract infection (UTI), utilizes an array of outer membrane iron receptors…”
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Host-pathogen interactions in urinary tract infection by Mobley, Harry L. T, Nielubowicz, Greta R

“…Urinary tract infections are experienced by a large section of the population and cause significant morbidity. Here, Nielubowicz and Mobley explain the…”
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Increased Incidence of Urolithiasis and Bacteremia During Proteus mirabilis and Providencia stuartii Coinfection Due to Synergistic Induction of Urease Activity by Armbruster, Chelsie E., Smith, Sara N., Yep, Alejandro, Mobley, Harry L T.

“…Background. Catheter-associated urinary tract infections (CaUTIs) are the most common hospital-acquired infections worldwide and are frequently polymicrobial…”
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Escherichia coli Isolates That Carry vat, fyuA, chuA, and yfcV Efficiently Colonize the Urinary Tract by SPURBECK, Rachel R, DINH, Paul C, WALK, Seth T, STAPLETON, Ann E, HOOTON, Thomas M, NOLAN, Lisa K, KWANG SIK KIM, JOHNSON, James R, MOBLEY, Harry L. T

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The Klebsiella pneumoniae citrate synthase gene, gltA, influences site specific fitness during infection by Vornhagen, Jay, Sun, Yuang, Breen, Paul, Forsyth, Valerie, Zhao, Lili, Mobley, Harry L T, Bachman, Michael A

“…Klebsiella pneumoniae (Kp), one of the most common causes of healthcare-associated infections, increases patient morbidity, mortality, and hospitalization…”
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MrpH, a new class of metal-binding adhesin, requires zinc to mediate biofilm formation by Jiang, Wangshu, Ubhayasekera, Wimal, Breed, Michael C, Norsworthy, Allison N, Serr, Nina, Mobley, Harry L. T, Pearson, Melanie M, Knight, Stefan D

“…Proteus mirabilis, a Gram-negative uropathogen, is a major causative agent in catheter-associated urinary tract infections (CAUTI). Mannose-resistant…”
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The oxidative fumarase FumC is a key contributor for E. coli fitness under iron-limitation and during UTI by Himpsl, Stephanie D, Shea, Allyson E, Zora, Jonathan, Stocki, Jolie A, Foreman, Dannielle, Alteri, Christopher J, Mobley, Harry L T

“…The energy required for a bacterium to grow and colonize the host is generated by metabolic and respiratory functions of the cell. Proton motive force,…”
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Fitness of Escherichia coli during urinary tract infection requires gluconeogenesis and the TCA cycle by Alteri, Christopher J, Smith, Sara N, Mobley, Harry L T

“…Microbial pathogenesis studies traditionally encompass dissection of virulence properties such as the bacterium's ability to elaborate toxins, adhere to and…”
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Immunization with the Yersiniabactin Receptor, FyuA, Protects against Pyelonephritis in a Murine Model of Urinary Tract Infection by Brumbaugh, Ariel R, Smith, Sara N, Mobley, Harry L T

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Fimbrial Profiles Predict Virulence of Uropathogenic Escherichia coli Strains: Contribution of Ygi and Yad Fimbriae by SPURBECK, Rachel R, STAPLETON, Ann E, JOHNSON, James R, WALK, Seth T, HOOTON, Thomas M, MOBLEY, Harry L. T

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Defining Genomic Islands and Uropathogen-Specific Genes in Uropathogenic Escherichia coli by LLOYD, Amanda L, RASKO, David A, MOBLEY, Harry L. T

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Pathogenic Potential of Proteus mirabilis Is Enhanced by Other Uropathogens during Polymicrobial Urinary Tract Infection by Armbruster, Chelsie E, Smith, Sara N, Johnson, Alexandra O, DeOrnellas, Valerie, Eaton, Kathryn A, Yep, Alejandra, Mody, Lona, Wu, Weisheng, Mobley, Harry L T

“…Urinary catheter use is prevalent in health care settings, and polymicrobial colonization by urease-positive organisms, such as Proteus mirabilis and…”
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Vaxign : The First Web-Based Vaccine Design Program for Reverse Vaccinology and Applications for Vaccine Development by He, Yongqun Oliver, Mobley, Harry L. T., Xiang, Zuoshuang

“…Vaxign is the first web-based vaccine design system that predicts vaccine targets based on genome sequences using the strategy of reverse vaccinology…”
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Waging War against Uropathogenic Escherichia coli: Winning Back the Urinary Tract by Sivick, Kelsey E, Mobley, Harry L.T

“…Urinary tract infection (UTI) caused by uropathogenic Escherichia coli (UPEC) is a substantial economic and societal burden--a formidable public health issue…”
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Uropathogenic Escherichia coli Outer Membrane Antigens Expressed during Urinary Tract Infection by Hagan, Erin C, Mobley, Harry L.T

“…Uncomplicated urinary tract infection (UTI) caused by uropathogenic Escherichia coli (UPEC) represents a prevalent and potentially severe infectious disease…”
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Fitness factor genes conserved within the multi-species core genome of Gram-negative Enterobacterales species contribute to bacteremia pathogenesis by Mobley, Harry L T, Anderson, Mark T, Moricz, Bridget S, Severin, Geoffrey B, Holmes, Caitlyn L, Ottosen, Elizabeth N, Eichler, Tad, Gupta, Surbhi, Paudel, Santosh, Sinha, Ritam, Mason, Sophia, Himpsl, Stephanie D, Brown, Aric N, Gaca, Margaret, Kiser, Christina M, Clarke, Thomas H, Fouts, Derrick E, DiRita, Victor J, Bachman, Michael A

“…There is a critical gap in knowledge about how Gram-negative bacterial pathogens, using survival strategies developed for other niches, cause lethal…”
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Identification of distinct capsule types associated with Serratia marcescens infection isolates by Anderson, Mark T, Himpsl, Stephanie D, Mitchell, Lindsay A, Kingsley, Leandra G, Snider, Elizabeth P, Mobley, Harry L T

“…Serratia marcescens is a versatile opportunistic pathogen that can cause a variety of infections, including bacteremia. Our previous work established that the…”
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