Search Results - "MLYNARCIKOVA, Alzbeta"
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Evaluation of effects of bisphenol analogs AF, S, and F on viability, proliferation, production of selected cancer-related factors, and expression of selected transcripts in Caov-3 human ovarian epithelial cell line
Published in Food and chemical toxicology (01-09-2024)“…Bisphenol A (BPA) has been a substantial additive in plastics until the reports on its adverse effects have led to its restrictions and replacement. Monitoring…”
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Bisphenol analogs AF and S: Effects on cell status and production of angiogenesis-related factors by COV434 human granulosa cell line
Published in Toxicology and applied pharmacology (01-09-2021)“…While Bisphenol A (BPA) has been a requisite plastic additive, as an endocrine disruptor it has been associated with adverse health effects including ovarian…”
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Bisphenol analogs AF, S and F: Effects on functional characteristics of porcine granulosa cells
Published in Reproductive toxicology (Elmsford, N.Y.) (01-08-2021)“…•BPAF, BPS and BPF (10−4 M) decreased FSH-stimulated progesterone production.•BPS significantly inhibited estradiol production from the concentration of 10−6…”
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Simultaneous effects of endocrine disruptor bisphenol A and flavonoid fisetin on progesterone production by granulosa cells
Published in Environmental toxicology and pharmacology (01-04-2018)“…•Flavonoid fisetin altered progesterone production by granulosa cells.•Fisetin was not able to restore progesterone synthesis impaired by the high dose of the…”
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Effect of selected bisphenol derivatives on nuclear receptor expression in ovarian cell line COV434
Published in Endocrine regulations (Bratislava) (01-10-2020)“…Bisphenol A (BPA), as an indispensable plastic additive, has also been proven as an endocrine disruptor associated with adverse health effects including…”
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Impact of endocrine disrupting chemicals on onset and development of female reproductive disorders and hormone-related cancer
Published in Reproductive biology (01-12-2016)“…Abstract A growing body of evidence suggests that exposure to chemical substances designated as endocrine disrupting chemicals (EDCs) due to their ability to…”
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Expression of selected nuclear receptors in human epithelial ovarian cell line Caov3 exposed to bisphenol derivatives
Published in Endocrine regulations (Bratislava) (01-01-2023)“…Bisphenol A (BPA) is an indispensable industrial chemical. However, as a proven endocrine disruptor, it may be associated with several health disturbances,…”
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Unique hyaluronan structure of expanded oocyte-cumulus extracellular matrix in ovarian follicles
Published in Endocrine regulations (Bratislava) (01-01-2024)“…In preovulatory follicles, after the endogenous gonadotropin surge, the oocyte-cumulus complexes (OCCs) produce hyaluronan (HA) in a process called “cumulus…”
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The use of ex vivo ovary culture for assessment of alterations in steroidogenesis following neonatal exposure to poly(ethylene glycol)-block-polylactide methyl ether or titanium dioxide nanoparticles in Wistar rats
Published in Endocrine regulations (Bratislava) (01-01-2020)“…Rapid development and widespread application of different types of nanoparticles (NPs) may result in increased exposure of humans and animals to NPs. Recently,…”
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Activation of cumulus cell SMAD2/3 and epidermal growth factor receptor pathways are involved in porcine oocyte-cumulus cell expansion and steroidogenesis
Published in Molecular reproduction and development (01-06-2011)“…Several lines of evidence suggest that in mice the activation of SMAD2/3 signaling by oocyte secreted factors, together with epidermal growth factor receptor…”
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Lapatinib inhibits meiotic maturation of porcine oocyte-cumulus complexes cultured in vitro in gonadotropin-supplemented medium
Published in Fertility and sterility (01-05-2013)“…Objective To determine whether inhibition of epidermal growth factor (EGF) receptor tyrosine kinase with lapatinib affects oocyte maturation, expression of the…”
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Effects of selected endocrine disruptors on meiotic maturation, cumulus expansion, synthesis of hyaluronan and progesterone by porcine oocyte–cumulus complexes
Published in Toxicology in vitro (01-04-2009)“…In most mammals, before ovulation, cumulus cells synthesize a large amount of hyaluronan (HA) that is organized into an extracellular matrix (ECM), which…”
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Alterations in steroid hormone production by porcine ovarian granulosa cells caused by bisphenol A and bisphenol A dimethacrylate
Published in Molecular and cellular endocrinology (01-12-2005)“…We have investigated the effects of bisphenol A (BPA) and BPA-dimethacrylate (BPA-DMA), endocrine disruptors used as plasticizers, on steroid hormone…”
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Development of functional LH Receptors on pig cumulus-oocyte complexes cultured in vitro by a novel two-step culture system
Published in Molecular reproduction and development (01-08-2009)“…We show in the present study that freshly isolated pig cumulus–oocyte complexes (COCs) display a limited response to LH, as assessed by the expression of…”
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Delayed adverse effects of neonatal exposure to polymeric nanoparticle poly(ethylene glycol)-block-polylactide methyl ether on hypothalamic–pituitary–ovarian axis development and function in Wistar rats
Published in Reproductive toxicology (Elmsford, N.Y.) (01-11-2015)“…•Neonatal exposure to polymeric nanoparticle PEG-b-PLA in female Wistar rats.•Delayed effects on hypothalamic–pituitary–ovarian axis development and function…”
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Effect of polymeric nanoparticle poly(ethylene glycol)-block-poly(lactic acid) (PEG-b-PLA) on in vitro luteinizing hormone release from anterior pituitary cells of infantile and adult female rats
Published in Neuro-endocrinology letters (2015)“…Polymeric PEG-b-PLA nanoparticles (NPs) were developed for delivery of poorly water-soluble drugs via blood brain barrier into brain parenchyma. We analyzed…”
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Endocrine-modulating effects of polymeric nanoparticle poly (ethylene glycol)-block-poly (lactic acid) (PEG-b-PLA) on ovarian steroidogenesis
Published in Toxicology letters (10-09-2014)Get full text
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Effects of selected nanoparticles on in vitro steroid hormone secretion by porcine ovarian granulosa cells
Published in Reproductive toxicology (Elmsford, N.Y.) (01-11-2013)Get full text
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Impact of endocrine disruptors on ovarian steroidogenesis
Published in Endocrine regulations (Bratislava) (01-10-2014)“…Production of steroid hormones by the ovary plays a key role in the female phenotype maintenance, as well as is critical for regular ovarian processes,…”
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