Search Results - "MIZUSHIMA, Tomoko"

The Cytostatic Effects of Lovastatin on ACC-MESO-1 Cells by Asakura, Keisuke, M.D, Izumi, Yotaro, M.D, Yamamoto, Michiko, M.S, Yamauchi, Yoshikane, M.D, Kawai, Kenji, M.S, Serizawa, Akihiko, M.D, Mizushima, Tomoko, M.S, Ohmura, Mitsuyo, M.S, Kawamura, Masafumi, M.D, Wakui, Masatoshi, M.D, Adachi, Takeshi, M.D, Nakamura, Masato, M.D, Suematsu, Makoto, M.D, Nomori, Hiroaki, M.D

“…Background Malignant pleural mesothelioma is known to be widely resistant to therapy, and new treatment strategies are needed. Statins are small molecules that…”
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Inhibition of DNA topoisomerases II and/or I by pyrazolo[1,5-a]indole derivatives and their growth inhibitory activities by Umemura, Ken, Mizushima, Tomoko, Katayama, Hajime, Kiryu, Yoshimitsu, Yamori, Takao, Andoh, Toshiwo

“…DNA topoisomerases (topos) I and II are molecular targets of several potent anticancer agents. Thus inhibitors of these enzymes are potential candidates or…”
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Efficient production of recombinant adeno-associated viral vector, serotype DJ/8, carrying the GFP gene by Hashimoto, Haruo, Mizushima, Tomoko, Chijiwa, Tsuyoshi, Nakamura, Masato, Suemizu, Hiroshi

“…•AAV, Serotype DJ/8 produced by the combination of lipofectamine and iodixanol produces is an efficient yield.•AAV, Serotype DJ/8 carrying GFP gene is produced…”
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Establishing EGFP Congenic Mice in a NOD/Shi-scid IL2Rgnull (NOG) Genetic Background Using a Marker-Assisted Selection Protocol (MASP) by SUEMIZU, Hiroshi, YAGIHASHI, Chie, MIZUSHIMA, Tomoko, OGURA, Tomoyuki, ETOH, Tomoo, KAWAI, Kenji, ITO, Mamoru

“…Severely immunocompromised NOD/Shi-scid IL2Rg null (NOG) mice, which show higher engraftment efficiency, are useful as recipients in xenotransplantation…”
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Practical ethics of animal experiments and a scoring system of potential pain in animals by Kagiyama, Naoko, Mizushima, Tomoko

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Fatty Acid β-Oxidation-dependent and -independent Responses and Tumor Aggressiveness Acquired Under Mild Hypoxia by Wakui, Masatoshi, Kawai, Kenji, Mizushima, Tomoko, Nishime, Chiyoko, Serizawa, Akihiko, Suemizu, Hiroshi, Asakura, Keisuke, Yamauchi, Yoshikane, Hayashida, Tetsu, Suematsu, Makoto, Murata, Mitsuru

“…The present study assessed whether and how tumor cells undergoing hypoxia contribute to disease progression after moving to areas with different oxygen…”
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Study on AAV-mediated gene therapy for diabetes in humanized liver mouse to predict efficacy in humans by Hashimoto, Haruo, Mizushima, Tomoko, Ogura, Tomoyuki, Kagawa, Takahiro, Tomiyama, Kayo, Takahashi, Ri-ichi, Yagoto, Mika, Kawai, Kenji, Chijiwa, Tsuyoshi, Nakamura, Masato, Suemizu, Hiroshi

“…Most in vivo studies on the conversion to insulin-producing cells with AAV carrying PDX1 gene are performed in rodents. However, there is little information…”
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Innate Response to Human Cancer Cells with or without IL-2 Receptor Common γ-Chain Function in NOD Background Mice Lacking Adaptive Immunity by Nishime, Chiyoko, Kawai, Kenji, Yamamoto, Takehiro, Katano, Ikumi, Monnai, Makoto, Goda, Nobuhito, Mizushima, Tomoko, Suemizu, Hiroshi, Nakamura, Masato, Murata, Mitsuru, Suematsu, Makoto, Wakui, Masatoshi

“…Immunodeficient hosts exhibit high acceptance of xenogeneic or neoplastic cells mainly due to lack of adaptive immunity, although it still remains to be…”
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Development of monoclonal antibodies for analyzing immune and hematopoietic systems of common marmoset by Kametani, Yoshie, Suzuki, Daisuke, Kohu, Kazuyoshi, Satake, Masanobu, Suemizu, Hiroshi, Sasaki, Erika, Ito, Toshio, Tamaoki, Norikazu, Mizushima, Tomoko, Ozawa, Manabu, Tani, Kenzaburo, Kito, Mitsuaki, Arai, Hideo, Koyanagi, Akemi, Yagita, Hideo, Habu, Sonoko

“…Objective Common marmosets are considered experimental animals of primates useful for medical research. We developed several monoclonal antibodies (mAbs)…”
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Abstract 456: Adaptation of cancer cells to hypoxic environments for tumor progression by Mizushima, Tomoko, Kawai, Kenji, Nishime, Chiyoko, Ohmura, Mitsuyo, Hayakawa, Eri, Matsuyama, Masahiro, Asakura, Keisuke, Izumi, Yotaro, Suemizu, Hiroshi, Ohnishi, Yasuyuki, Nakamura, Masato, Suematsu, Makoto, Wakui, Masatoshi

“…There have been a number of reports mentioning the significance of adaptation of cancer cells to hypoxic environments in tumor growth, invasion, and…”
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Metabolomic profiling of the liver bearing human colon cancer metastasis in superimmunodeficient NOG mice by Ohmura, Mitsuyo, Handa, Kan, Nishime, Chiyoko, Mizushima, Tomoko, Kawai, Kenji, Hishiki, Takako, Yamamoto, Takehiro, Wakui, Masatoshi, Suemizu, Hiroshi, Nakamura, Masato, Suematsu, Makoto

“…Hypoglycemia is one of the important events in paraneoplastic syndrome caused by solid tumors. Although metabolic feature of solid tumors characterized by…”
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Abstract 2366: Reduced ecto-5′-nucleotidase CD73 expression and altered purine nucleotide metabolism in colorectal cancer cells robustly causing liver metastases by Matsuyama, Masahiro, Wakui, Masatoshi, Monnai, Makoto, Mizushima, Tomoko, NIshime, Chiyoko, Kawai, Kenji, Suemizu, Hiroshi, Hishiki, Takako, Suematsu, Makoto, Murata, Mitsuru, Chijiwa, Tusyoshi, Furukawa, Daisuke, Ogoshi, Kyoji, Makuuchi, HIroyasu, Nakamura, Masato

“…Liver metastases are frequently inoperative and severely impact the prognoses of patients with cancers. Colorectal cancers as well as pancreatic cancers most…”
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Establishing EGFP congenic mice in a NOD/Shi-scid IL2Rg(null) (NOG) genetic background using a marker-assisted selection protocol (MASP) by Suemizu, Hiroshi, Yagihashi, Chie, Mizushima, Tomoko, Ogura, Tomoyuki, Etoh, Tomoo, Kawai, Kenji, Ito, Mamoru

“…Severely immunocompromised NOD/Shi-scid IL2Rg (null) (NOG) mice, which show higher engraftment efficiency, are useful as recipients in xenotransplantation…”
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Reduced CD73 expression and its association with altered purine nucleotide metabolism in colorectal cancer cells robustly causing liver metastases by MATSUYAMA, MASAHIRO, WAKUI, MASATOSHI, MONNAI, MAKOTO, MIZUSHIMA, TOMOKO, NISHIME, CHIYOKO, KAWAI, KENJI, OHMURA, MITSUYO, SUEMIZU, HIROSHI, HISHIKI, TAKAKO, SUEMATSU, MAKOTO, MURATA, MITSURU, CHIJIWA, TSUYOSHI, FURUKAWA, DAISUKE, OGOSHI, KYOJI, MAKUUCHI, HIROYASU, NAKAMURA, MASATO

“…Liver metastases of colorectal cancers significantly affect the prognoses of patients. To further understand the biological aspects of the metastatic…”
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Establishing EGFP Congenic Mice in a NOD/Shi-scid IL2Rg super(null) (NOG) Genetic Background Using a Marker-Assisted Selection Protocol (MASP) by Suemizu, Hiroshi, Yagihashi, Chie, Mizushima, Tomoko, Ogura, Tomoyuki, Etoh, Tomoo, Kawai, Kenji, Ito, Mamoru

“…Severely immunocompromised NOD/Shi-scid IL2Rg super(null) (NOG) mice, which show higher engraftment efficiency, are useful as recipients in xenotransplantation…”
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