Search Results - "MIZUNO, Satoru"
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Where do substrates of diacylglycerol kinases come from? Diacylglycerol kinases utilize diacylglycerol species supplied from phosphatidylinositol turnover-independent pathways
Published in Advances in biological regulation (01-01-2018)“…Diacylglycerol kinase (DGK) phosphorylates diacylglycerol (DG) to produce phosphatidic acid (PA). Mammalian DGK comprises ten isozymes (α–κ) and regulates a…”
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Development of a liquid chromatography-mass spectrometry based enzyme activity assay for phosphatidylcholine-specific phospholipase C
Published in Analytical biochemistry (01-06-2017)“…Phosphatidylcholine (PC)-specific phospholipase C (PC-PLC) hydrolyzes PC to generate the second messenger 1,2-diacylglycerol (DG) and phosphocholine. PC-PLC…”
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The Induction of Antigen 85B-Specific CD8 + T Cells by Recombinant BCG Protects against Mycobacterial Infection in Mice
Published in International journal of molecular sciences (04-01-2023)“…(Mtb) infection remains a major health problem worldwide. Although the Bacillus Calmette-Guérin (BCG) vaccine is the most widely used vaccination for…”
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4
Culture filtrate proteins from BCG act as adjuvants for cytotoxic T lymphocyte induction
Published in Frontiers in immunology (18-10-2023)“…Mycobacterium bovis bacilli Calmette-Guerin (BCG) is a licensed vaccine against tuberculosis. It requires attenuated live bacteria to be effective, possibly…”
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SOCS1 Antagonist-Expressing Recombinant Bacillus Calmette-Guérin Enhances Antituberculosis Protection in a Mouse Model
Published in The Journal of immunology (1950) (01-07-2019)“…Suppressor of cytokine signaling 1 (SOCS1) plays a key role in the negative regulation of JAK/STAT signaling, which is involved in innate immunity and…”
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A novel diacylglycerol kinase α-selective inhibitor, CU-3, induces cancer cell apoptosis and enhances immune response[S]
Published in Journal of lipid research (01-03-2016)“…Diacylglycerol kinase (DGK) consists of 10 isozymes. The α-isozyme enhances the proliferation of cancer cells. However, DGKα facilitates the nonresponsive…”
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Diacylglycerol Kinases as Emerging Potential Drug Targets for a Variety of Diseases: An Update
Published in Frontiers in cell and developmental biology (17-08-2016)“…Ten mammalian diacylglycerol kinase (DGK) isozymes (α-κ) have been identified to date. Our previous review noted that several DGK isozymes can serve as…”
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Mycobacterial mycolic acids trigger inhibitory receptor Clec12A to suppress host immune responses
Published in Tuberculosis (Edinburgh, Scotland) (01-01-2023)“…Mycobacteria often cause chronic infection. To establish persistence in the host, mycobacteria need to evade host immune responses. However, the molecular…”
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Estimation of maximum Bio-coke compressive strength based on chemical composition
Published in Mechanical Engineering Journal (2021)“…Effective utilization of biomass, including wood, is necessary for environmental sustainability. Bio-coke is a solid biofuel made from plant biomass. Bio-coke…”
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Distinct 1-monoacylglycerol and 2-monoacylglycerol kinase activities of diacylglycerol kinase isozymes
Published in Biochimica et biophysica acta (01-09-2016)“…Diacylglycerol kinase (DGK) consists of ten isozymes and is involved in a wide variety of patho-physiological events. However, the enzymological properties of…”
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11
Evaluation of energy properties of torrefied biomass for a given pyrolysis condition by isothermal pyrolysis kinetics
Published in Mechanical Engineering Journal (01-01-2021)“…One of the effective solutions to reduce CO2 emission derived from fossil fuels is the suppression of coal consumption in industrial boilers and power plants…”
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Primary Role of Suppressor of Cytokine Signaling 1 in Mycobacterium bovis BCG Infection
Published in Infection and immunity (01-11-2018)“…Suppressor of cytokine signaling 1 (SOCS1) is a negative regulator of JAK/STAT signaling and is induced by mycobacterial infection. To understand the major…”
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Recombinant BCG-Prime and DNA-Boost Immunization Confers Mice with Enhanced Protection against Mycobacterium kansasii
Published in Vaccines (Basel) (01-11-2021)“…The incidence of infections with nontuberculous mycobacteria (NTM) has been increasing worldwide. The emergence of multidrug-resistant NTM is a serious…”
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14
Activation of conventional and novel protein kinase C isozymes by different diacylglycerol molecular species
Published in Biochemistry and biophysics reports (01-09-2016)“…A variety of diacylglycerol (DG) molecular species are produced in stimulated cells. Conventional (α, βII and γ) and novel (δ, ε, η and θ) protein kinase C…”
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Recombinant Ag85B vaccine by taking advantage of characteristics of human parainfluenza type 2 virus vector showed Mycobacteria-specific immune responses by intranasal immunization
Published in Vaccine (26-03-2014)“…Highlights • We assessed the effectiveness of novel mucosal vaccine using recombinant human parainfluenza type 2 virus (rhPIV2) for TB (rhPIV2–Ag85B). •…”
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Effect of specimen size on ultimate compressive strength of Bio-coke produced from green tea grounds
Published in Mechanical Engineering Journal (01-01-2016)“…Various sizes of high-density biomass briquette, named ‘Bio-coke,’ were produced from spent green tea grounds. The mechanical properties at room temperature of…”
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Extinction of laminar jet diffusion microflames
Published in Proceedings of the Combustion Institute (2009)“…This paper presents a theory to predict the extinction limit of laminar jet diffusion microflames, defined as flames established on submillimeter-diameter…”
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Mycobacterial Infection in TLR2 and TLR6 Knockout Mice
Published in Microbiology and immunology (01-01-2003)“…To investigate the role of TLR in the development of murine tuberculosis in vivo, TLR2 and TLR6 knockout (KO) mice were infected with Mycobacterium…”
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Higher Susceptibility of Type 1 Diabetic Rats to Mycobacterium tuberculosis Infection
Published in The Tohoku Journal of Experimental Medicine (2008)“…An association between diabetes mellitus and tuberculosis has been implicated for a long time. We have previously reported that Goto Kakizaki type 2 diabetic…”
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Role of Interleukin-18 (IL-18) in Mycobacterial Infection in IL-18-Gene-Disrupted Mice
Published in Infection and Immunity (01-05-1999)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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